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The present study was designed to detect the impact of fertility, histopathalogical and the cytotoxicity effect of ferula hermonis extract on male albino mice. To study the effect of F. hermonis, methanolic roots extract was prepared and chemical detection of flavonoids, alkaloids, tannins, saponins, terpenes and steroids was carried out. The Thin Layer Chromatography analysis of methanolic extract showed that ferutinine was present based on RF value. The effect of methanolic extract included an assays on the sperm functions including concentration of sperms in semen fluid, percentage of morphologically abnormal sperms and also included an assay testosterone concentration in serum.
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