Books in the Advanced Biotechnology series

Provides a comprehensive treatment of the underlying concepts and the practical applications in metabolic engineering.

This book not only introduces the reader to the necessary tools to understand microbiome but also discusses many relevant areas of current research and applications of microbiome engineering, ranging from human diseases to husbandry, food and beverage applications.

A comprehensive overview of the various aspects of systems biology, giving an introduction to specific branches and highlighting current state-of-the-art approaches to cell factory engineering and the improvement of human health.

A comprehensive overview of the topic, highlighting recent developments, ongoing research trends and future directions. Experts from Europe, Asia and the US cover five core areas of imminent importance to the food, feed, pharmaceutical and water treatment industries in terms of sustainable and innovative processing and production.

Part of the "Advanced Biotechnology" series, this volume covers all important aspects of cell culture engineering as applied to the production of recombinant proteins for therapeutic use, from molecular biology to bioprocess engineering. With a focus on mammalian and animal cells, the book describes the challenges in cell line development and cell engineering, while providing an overview of synthetic and systems biology approaches applied to cell culture engineering. In addition, the authors elaborate the use of CHO cells as common cell line for protein production and discuss current perspectives in production processes, including cell culture media, batch, fedΓÇôbatch and perfusion processes, as well as process analytical technology, quality by design and scale down models.