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This series provides coverage of all aspects of the molecular basis of human cancer, functions of oncogenes, and research strategies for cancer drug development and treatment. This volume includes a chapter on effectors of signal transduction and GI progression,
This volume comprises the cumulative subject index covering volumes 50-72 of the series "Advances in Cancer Research". It includes references to specific articles on topics such as breast cancer, prostrate cancer, Kaposi's sarcoma, Burkitt's lymphoma, leukemias, oncogenes and tumour genetics.
This text discusses the roles of p53 and ATM in cell cycle progression and cell death in response to DNA damage and how this information may lead to improved cancer therapies. Other areas of study covered include the methodological advantages and limitations to localizing tumour suppressor genes.
GPCR Signaling in Cancer, Volume 145, the latest release in the Advances in Cancer Research series, highlights recent developments in the area of GPCRs and cancer biology. Chapters included in this volume cover several GPCRs and their downstream effectors as case examples to highlight their fundamental understanding and therapeutic potential. Specific chapters address the Role of GRKs and beta-arrestins in cancer, Atypical GPCRs in cancer, the Role of a chemokine receptor (CCR) 5 in cancer, Targeting G protein-coupled receptors for therapeutics in cancer, Emerging GPCR signaling pathways in cancer, and more. G protein-coupled receptors (GPCRs) constitute a large family of cell surface receptors which are involved in nearly every cellular and physiological event. These receptors can recognize a broad array of ligands and they are targeted by nearly one third of the currently prescribed drugs including anti-cancer therapeutics. Covers the latest concepts in GPCR signaling and their relevancy to cancer biologyPresents new indications for anti-cancer therapeutic programsIncludes sections on cross-talk and signaling networks of GPCRs and effectors in molecular oncology and therapeutics
Advances in Cancer Research, Volume 144, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research. Chapters in this new release include Gene-Environment-Microenvironment Interactions in Melanomagenesis, PP2A and the Cell Cycle, Current Progress Defining Calcium Signals as Therapeutic Targets in Cancer Cells, and much more. Provides the latest information on cancer researchOffers outstanding and original reviews on a range of cancer research topicsServes as an indispensable reference for researchers and students alike
Provides information on the field of cancer research. The key features of this work include: The Yin Yang of TCF/b-Catenin Signalling; Biochemical and Clinical Implications of the Erb/HER Signaling Network of Growth Factor Receptors; p53 and Human Cancer: The First Ten Thousand Mutations; Macrophage Stimulating Protein; and more.
Provides information on the field of cancer research. This title presents original reviews on a variety of topics.
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