Books in the Advances in Experimental Medicine and Biology series

This book will contain the proceedings of the XIV International Symposium on Retinal Degeneration (RD2010), held July 13-17, 2010, in Mont-Tremblant, Quebec, Canada. and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy.

He titled his Nobel Lecture "Immunological Recognition of Self" emphasizing the central argument of immunological tolerance in "How does the vertebrate organism recognize self from nonself in this the immunological sense-and how did the capacity evolve." The concept of self is linked to the concept of biological self identity.

This volume has a strong focus on homo-oligomerization, which is surprisingly common. However, protein function is so often linked to both homo- and hetero-oligomerization and many heterologous interactions likely evolved from homologous interaction, so this volume also covers many aspects of hetero-oligomerization.

Hot Topics in Infection and Immunity IX

This meeting was the fourth in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen presentation and adaptive immunity.

This volume describes chemical approaches to assess ion channel structure, function and pharmacology.

This book will contain a series of solicited chapters that concern with the molecular machines required by viruses to perform various essential functions of virus life cycle.

An increasing number of workers from different fields have turned to insects, fish, worms and other model hosts as facile, ethically expedient, relatively simple, and inexpensive hosts to model a variety of human infectious diseases and to study host responses and innate immunity.

The Second International Conference on the Effects of Noise on Aquatic Life will take place in Ireland August 15-20, 2010. The Second conference will place strong emphasis on recent research results, the sharing of ideas, discussion of experimental approaches, and analysis of regulatory issues.

The International Society for Systems Biology (ISSB) is a society aimed at advancing world-wide systems biology research by providing a forum for scientific discussions and various academic services. The ISSB helps coordinate researchers to form alliances for meeting the unique needs of multidisciplinary and international systems biology research.

Limiting genome replication to once per cell cycle is vital for maintaining genome stability. Although polyploidization is of physiologically importance for several specialized cell types, inappropriate polyploidization is believed to promote aneuploidy and transformation.

The aim of this book is to summarize our understanding on the insect nicotinic acetylcholine receptors. We need to be precise in identifying the subunit composition of native insect nicotinic receptor subtypes, their functional properties and physiological roles.

This book attempts to analyze the latest discoveries in sphingolipid biology and how the alteration of their metabolism leads to altered signaling events and to the development of pathobiological disorders, such as cancer, cardiovascular diseases, asthma, diabetes, inflammation and infectious diseases.

This book is a collection of articles written by prominent scientists who gathered in the city of Recife, Brazil, 23-27 October 2010, celebrating the 10th International Symposium on Yersinia.

Book covers course with topics in infectious diseases in children and is intended for Pediatric Infectious disease clinical researchers, trainees, trainers, and all those who manage the research of children with infections and the children themselves.

Biological systems are an emerging discipline that may provide integrative tools by assembling the hierarchy of interactions among genes, proteins and molecular networks involved in sensory systems. The aim of this volume is to provide a picture, as complete as possible, of the current state of knowledge of sensory systems in nature.

These challenges have prompted an intensive search for new prophylactic and therapeutic strategies in order to prevent infants from acquiring HIV infection through breastfeeding. In this book, expert HIV researchers critically review every aspect of this highly evolving and topical subject.

When Foord and his colleagues discovered that a single transmembrane protein called Receptor Activity Modifying Proteins (RAMPs) could modulate the surface expression of GPCRs of the calcitonin family, it widely opened the field of receptor life cycle.

Scientists interested in the regulation and modulation of components of the immune system found a whole variety of NAbs to cytokines with regulatory and protective functions and NAbs that modulate, e.g., dendritic cells, regulatory T cells, B cells and granulocytes.

This book addresses the role of tandem repeat polymorphisms (TRPs) in genetic plasticity, evolution, development, biological processes, neural diversity, brain function, dysfunction and disease.

Conversely, medical doctors who want to update their knowledge of NPC biology will benefit from chapters on viral and cellular oncogenesis and various aspects of host-tumor interactions.

Biobanking, an emerging field supported by academia, industry and health administrators alike, is distinctly different today from the practice that once defined it. The book outlines the experiences of developing modern Biobanking repositories in different countries, whilst covering specific topics regarding the many aspects of Biobanking.

This meeting was the fifth in a series, and assembled a team of scientists working on mechanisms by which the innate immune system of the host senses pathogens, the cellular and signaling networks that orchestrate the innate response and antigen presentation and adaptive immunity.

Fish Hearing and Bioacoustics is an anthology of review papers that were presented at a special symposium to honor Arthur Popper and Richard Fay on May 25th 2013 at the Mote Marine Laboratory in Sarasota, FL.

Men are routinely treated with drugs that can impair or abolish fertility. Although practitioners in the field of reproductive medicine generally realize that certain drugs impact negatively on reproductive health, there are limited resources providing evidence-based knowledge useful in counseling patients.