Books in the Advances in Genome Biology series

Genetic diseases which are inherited, can be diagnosed prenatally; an idea that was once inconceivable. This book reflects on the importance of molecular genetics in modern medicine. It also describes the special role of molecular genetics in combating genetic diseases through gene therapy.

The fortuitous findings of XX males and XY female, which are generally termed sex reversal phenomenon, have opened new avenues to explore further the genetic basis of sex determination at the single gene level. This volume aims to reflect on the advances and investigative directions.

Explosive growth in the discipline of cancer genetics is so rapid that any attempt to review this subject becomes rapidly outdated and continuous revisions are warranted. The identification of over 50 oncogenes has led to a better understanding of the physiological process. Here, the contributors provide accounts of their fields of expertise.