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Contains four detailed accounts of the close interface between synthetic chemistry, structure-activity relationships, biochemistry and pharmacology. This work includes a comprehensive survey of the immunophilin area focussing on neuroregenerative applications in the central nervous system.
Comprises of six chapters on a range of topics in medicinal chemistry, including molecular modeling, structure-based drug design, organic synthesis, peptide conformational analysis, biological assessment, structure-activity correlation, and lead optimization.
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