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Explores the state of Alzheimer's disease research and therapeutics. In this title, chapters cover such topics as the B cell targeted therapies, Lymphotoxin family receptors in inflammation, and allergic inflammation and thymic stromal lymphopoietin.
Presents catecholamine symposium proceedings. This title includes chapters that cover such topics as cellular dynamics of catecholamine release and re-uptake, catecholamines in mood regulation and imaging catecholamine transporters.
Suitable for pharmacologists, immunologists and biochemists alike, this title explores the antiviral agents. It includes chapters that cover such topics as virus entry inhibitors, interferon-free drug combinations, and antiviral agents for HSV.
From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Volume 88, the latest release in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this updated edition include Targeting muscarinic M1 receptor in neurodegeneration, Photo-switchable allosteric ligands, Computational approaches for the design of mGlu receptor allosteric modulators, Allosteric modulation of GLP-1 receptor in metabolic disorders, Group II mGluR roles in the nervous system and their roles in addiction, RAMPs as allosteric modulators of Class B GPCRs, Structure-based discovery and development of mGlu5 NAMs, and much more. Includes the authority and expertise of leading contributors in pharmacologyPresents the latest release in the Advances in Pharmacology series
Suitable for pharmacologists, immunologists and biochemists alike, this title explores the state of Alzheimer's disease research and therapeutics. It includes chapters that cover topics such as the role heat shock proteins play in the Alzheimer's Theater, and Gamma-Secretase as a Target for Alzheimer's Disease.
Development of targeted cancer therapies has already shown promise in a limited number of cancer types. As basic cancer research and drug development continues, we expect this number to grow and more patients to benefit from these advances. This book brings together some of foremost basic science and clinical researchers.
Explores the modern experimental and conceptual framework for drug discovery for G protein coupled receptors. This title also explores advances in structure determination and structure-based drug design as well as concepts of allosteric modulation, functional selectivity/biased agonism, and pharmacological chaperones.
Offers an overview of the field of purinergic signalling through adenosine and ATP receptors.
Presents a collection of reviews and places emphasis on the molecular basis of drug action, both applied and experimental. This title includes articles written by some of the leading investigators in the field.
Provides a review of the scientific and regulatory perspectives of drug-drug interactions from the point-of-view of academia, industry, and government regulatory agencies. This book is intended for professionals in the pharmaceutical industry, health care, and governmental regulatory agencies.
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