Books in the Chapman & Hall/CRC Interdisciplinary Statistics series

This book explores the ways in which statistical models, methods, and research designs can be used to open new possibilities for APC analysis. Within a single, consistent HAPC-GLMM statistical modeling framework, the authors synthesize APC models and methods for three research designs: age-by-time period tables of population rates or proportions, repeated cross-section sample surveys, and accelerated longitudinal panel studies. They show how the empirical application of the models to various problems leads to many fascinating findings on how outcome variables develop along the age, period, and cohort dimensions.

Biology is at the beginning of a new era, promising significant discoveries that will be characterized by information-packed databases. This text offers a textbook treatment of the combinatorial and statistical problems that will arise in this new era.

Addresses statistical challenges posed by inaccurately measuring explanatory variables, a common problem in biostatistics and epidemiology. This book explores both measurement error in continuous variables and misclassification in categorical variables. It is suitable for biostatisticians, epidemiologists, and students.

The third edition of the bestselling Clinical Trials in Oncology provides a concise, nontechnical, and thoroughly up-to-date review of methods and issues related to cancer clinical trials. The authors emphasize the importance of proper study design, analysis, and data management and identify the pitfalls inherent in these processes. In addition, the book has been restructured to have separate chapters and expanded discussions on general clinical trials issues, and issues specific to Phases I, II, and III. New sections cover innovations in Phase I designs, randomized Phase II designs, and overcoming the challenges of array data. Although this book focuses on cancer trials, the same issues and concepts are important in any clinical setting. As always, the authors use clear, lucid prose and a multitude of real-world examples to convey the principles of successful trials without the need for a strong statistics or mathematics background. Armed with Clinical Trials in Oncology, Third Edition, clinicians and statisticians can avoid the many hazards that can jeopardize the success of a trial.

Due to recent advances in methodology that offer significant improvements over conventional methods, there is increasing interest in the use of time series models for the study of neuroscience data such as EEG, MEG, fMRI, and NIRS. Written by one of the pioneers of these methods, this book presents an overview of time series models for the study of neuroscience data. It is accessible to applied statisticians working with neuroscience data as well as quantitatively trained neuroscientists. The book is supported by many real examples to illustrate the methods provides computational toolbox on the web, which enables readers to apply the methods to real data.

Offers a review of methods for cluster detection, organized according to the different types of hypotheses that can be investigated using these techniques. This book presents various methods that allow for detection of emergent geographic clusters. It includes actual datasets and simplified examples to illustrate key concepts.

Emphasizing model choice and model averaging, this book presents Bayesian methods for analyzing complex ecological data. It provides a basic introduction to Bayesian methods that assumes no prior knowledge. It includes descriptions of methods that deal with covariate data and covers techniques at the forefront of research.

Presents developments in statistical methodology with a number of worked examples that outline how these methods can be applied. This title provides key tools needed to understand and model the genetic variation for drug response and equips statisticians with an understanding of this complex field and how computational skills can be employed.

Covers many of the diverse methods in applied probability and statistics. This book also emphasizes the variety of practical situations in insurance and actuarial science where these techniques may be used. It examines generalized linear models, credibility theory, game theory, and simulation techniques and contains numerous examples and problems.

This work introduces Markov chain Monte Carlo methodology at a level suitable for applied statisticians. It explains the methodology and its theoretical background, summarizes application areas, and presents illustrative applications in many areas including archaeology and astronomy.

Discusses variable models, including multilevel or generalized linear mixed models, longitudinal or panel models, item response or factor models, latent class or finite mixture models, and structural equation models. This work explains a range of estimation and prediction methods from biostatistics, psychometrics, econometrics and statistics.