Books in the Chromatographic Science Series series

This book discusses flow perturbation method, namely, the stopped-flow technique and the reversed-flow technique. It is directed to those who need an accurate method for the determination of a certain physicochemical quantity and to researchers working on the development of gas chromatography.

Introduces scientists of various disciplines to the chromatographic process and how it functions. This title covers the basic principles of chromatographic separation and specific chromatographic procedures, including gas, liquid and thin-layer chromatography. It is suitable for analytical chemists and graduate students in analytical chemistry.

Presents practical information on the application of capillary electrophoresis (CE) to protein analysis, with an emphasis on developing and optimizing CE techniques in the laboratory. This title includes separation methods bases on mass, charge, isoelectric point, molecular sieving, and affinity interactions.

Comprehensively covers the design, construction, and operation of gas chromatography, liquid chromatography, and thin-layer chromatography detectors. This title emphasizes the essential use of common specifications to describe various detectors, allowing easy comparison of their attributes.

This volume is the first book to give a complete description of the techniques, materials, and instrumentation of column HPLC and its application to essentially all primary and secondary plant metabolites. It describes the techniques and instrumentation of HPLC analysis, such as HPLC/nuclear magnetic resonance spectrometry, HPLC with photodiode array detection, and HPLC chiral analysis. It explores the application of HPLC to primary and secondary plant metabolites and discusses how HPLC is used for analyzing herbal drugs and dietary supplements.

This book provides a detailed description of technical elements of a microbore column liquid chromatograph suitable for use in trace analysis. It presents examples of analyses, especially from the spheres of biochemistry, pharmacology, and environmental analytical chemistry.

Considers three fundamental aspects of molecular interactions important in chromatography, taking care not to duplicate information readily available in other references. Surveys the basic factors involved in complex formation, which governs the retention mechanism and selectivity in either donor or

This book discusses flow perturbation method, namely, the stopped-flow technique and the reversed-flow technique. It is directed to those who need an accurate method for the determination of a certain physicochemical quantity and to researchers working on the development of gas chromatography.

This important, new reference provides the first , up-to-date, and comprehensive treatmentof the various liquid chromatography (LC) instrumentation for Therapeutic DrugMonitoring (TDM) and toxicology drug assays and reviews the clinical pharmacologyof major classes of drugs and their LC analyses

This book gives the pertinent information on the high pressure liquid chromatography (HPLC) analyses of all the compounds of interest in nucleic acid metabolism. It aids chromatographers, biochemists, biomedical researchers, and chemists by giving information on applications of HPLC technique.

This book describes new gel permeation chromatography/liquid chromatography applications and techniques that will provide polymer scientists and practitioners with insight into the development of new polymers and plastics and improvement of existing materials.

This book describes the various aspects of microbore column chromatography. It provides readers with an in-depth understanding of the supercritical fluid chromatography and microbore high-performance liquid chromatography.

This book informs the reader about the practical methods, possibilities, and limits of template chromatography. It shows the various techniques for immobilization of nucleic acids fragments, polynucleotides, and nucleic acids by which the desired separation of materials can be achieved.

Covering advancements in separation technique, this book presents concepts including monolithic columns, bonded stationary phases, micro-HPLC, two-dimensional comprehensive liquid chromatography, and capillary electromigration techniques. It covers areas of HPLC application, including chiral pharmaceutical, food, and forensic analysis.

Focuses on TLC which applies to the separation, identification, quantification, and isolation of medicinal plant components. This title offers an overview of TLC and phytochemistry. It emphasizes real strategies and procedures for analyzing various types of primary and secondary plant metabolites.

This book summarizes all the important aspects of multidimensional separations, providing information on gas, liquid and thin-layer chromatography, as well as the techniques and applications of supercritical fluid chromatography in the multidimensional mode.

This book documents the principles of operation, the advantages and drawbacks, and the potential future of currently available liquid chromatographic detectors. In offering a snapshot of the current technology, it provides clear explanations and possible new horizons for both beginners and experts.

This book covers a range of topics of interest to those involved in the fractionation and characterization of polymeric substances. It deals with problems that are encountered in modern gel permeation chromatography with dual detection when calculating average molecular weights.

Shows how to choose the most effective techniques for assessing the toxicity of chemicals in both food and the environment. This title examines a range of volatile compounds from toxic aldehydes and pesticides to micotoxins and dioxins.

Focuses on the various aspects of the microfluidic lab-on-a-chip technologies and offers an overview of the available technology, its limitations and its breakthroughs over the years. This work emphasizes analytical applications of microfluidic technology and offers coverage of micromachining methods, microfluidic operations and injection methods.

A great deal of confusion and uncertainty over genotoxic impurity (GTI) identification, assessment, and control exists. This book strives to facilitate scientific and systematic consensus on GTI management by presenting rationales, strategies, practices, and case studies from the pharmaceutical industry. Exploring the safety, quality, and regulatory aspects of GTIs, the text explains the how and why of various GTI control tactics and practices, including GTI control examples in drug substance and drug product development processes from large and small pharmaceutical firms in multiple geographical regions.

Explains to chromatographers that gas-liquid chromatography, a development of gas chromatography, is itself just a limited case of gas-liquid-solid chromatography.

This thoughtfully constructed edited reference presents the main chromatographic methodologies and strategies used to discover and analyze novel designer drugs contained in diverse biological materials.

Explores the chromatographic methods used for the measurement of drugs, impurities, and excipients in pharmaceutical preparations - such as tablets, ointments, and injectables. This title contains a table listing the chromatographic data of over 1300 drugs and related substances - including sample matrix analyzed and sample handling procedures.

Presenting a constructive evaluation of the most significant developments in liquid chromatography - mass spectrometry (LC-MS) and its uses for quantitative bioanalysis and characterization for a diverse range of disciplines, this title offers coverage of the technological developments and applications.