Books in the Developments in Cardiovascular Medicine series

Since plaque disruption, plaque erosion, and acute intracoronary thrombus formation play major roles in the pathophysiology of both unstable angina and acute myocardial infarction, and since the two disease entities represent a continuum of coronary ischemic syndromes, it is appropriate to discuss the two disease states in a single monograph.

Over two centuries ago, oxygen was discovered as "air vital": the component of the earth's atmosphere necessary for life. The deleterious ef fects of oxygen radicals and activated oxygen species on a variety of biological systems have now been described.

Our understanding of the pathophysiology of acute myocardial infarction has grown enormously in recent years.

A detailed description of available to the clinician and the researcher, laser recanalization techniques is presented for which often makes the choice of a laser system the various systems in the clinical setting.

Thus, the book attempts ro It is because of such positive comments and reactions that the publisher and I decided to embark on a integrate all relevant aspects of the factors influenc second edition of Physiology and Pathophysiology of the ing the function of the heart as a vital organ under Heart.

The need for a second edition of Cardiovascular Physiology in the Genetically Engineered Mouse is underscored not only by these rapid advances, but by the increasing numbers of scientists who have focussed their research on genetically engineered mice.

Heat shock proteins (HSP) were originally described in heat-shocked drosophila by Ritossa in the early 1960's. The purpose of this volume is to give an overview of our current understanding of the heat shock proteins in the cardiovascular system, and to summarize the approaches to the study of heat shock proteins in the heart.

Here, Professor Sperelakis not only defines the equations and underlying concepts of membrane potentials, but gives working examples of solutions, thus allowing investigators to utilize the fundamental principles in their research, and students of membrane physiology to establish a sound basis of electrophysiological theory.

Molecular Cardiology for the Cardiologist provides a short, easily readable summary of what the new biology brings to cardiology. The five parts of the book provide a general introduction to the new language of biology; the physiopathology and the new therapeutic avenues that have been opened up by the new biology.

During the last decade we have witnessed a rapid expansion of our knowledge of the role of the endothelium in the control of vascular tone and hemostasis.

To the extent, however, that physicians who utilize ICDs are not sufficiently comfortable with or familiar with the engineering principles that guide ICD function, the full clinical potential of even an ideal device will not be realized.

a process brought about by the insertion of a gene coding for a foreign protein into target cells resulting in the synthesis of the foreign protein For gene therapy, a tmnsferred therapeutic gene must be expressed at a level beneficial for the patient.

For over a quarter of a century, echocardiography has made an unparalleled contribution to clinical cardiology as a major tool for real-time imaging of cardiac dynamics.

Stress Echocardiography - Its Role in the Diagnosis and Evaluation of Coronary Artery Disease - Second Edition by Thomas Marwick is a concise, practical guide for anyone new to the field of stress echocardiography or an excellent summary of the existing evidence base for the experienced user.

Molecular Cardiology for the Cardiologist, Second Edition provides a short, easily readable summary of what the new biology brings to cardiology.

Proceedings of the Symposium on the Diabetic Heart sponsored by the Council of Cardiac Metabolism of the International Society and Federation of Cardiology held in Tokyo, Japan, October 1989

Although there are many books on angina, few are devoted to the important problem of how to evaluate drug efficacy in angina pectoris.

After exploratory surveys in countries with supposed differences in dietary patterns, lifestyle and heart disease rates in the early 1950s, the Seven Countries Study took off in 1958.

Despite approximately 50 years of progress in the management of com plex congenital heart disease, hypoplastic left heart syndrome (HLHS) has been one of the last cardiac malformations to yield to effective surgical treat ment.

Furthermore, our understanding of the multiple roles that mitochondria play in cardiac cell homeostasis opened the door for intensive experimentation to understand the pathogenesis and to find new treatments for cardiovascular diseases.

In June 1989, a third conference concentrating on the progress in quantita tive coronary angiography and related techniques was held in Rotterdam, again very successful as the two preceding events in 1985 and 1987.

The need for a second edition of Cardiovascular Physiology in the Genetically Engineered Mouse is underscored not only by these rapid advances, but by the increasing numbers of scientists who have focussed their research on genetically engineered mice.

Participation in athletics at both the recreational and competitive levels has grown enormously over the last decade, and now involves a substantial segment of the population of many countries, particularly those in Europe and North America.

In Heart Cell Communication in Health and Disease an extensive review of different aspects of heart cell communication is presented.

Proceedings of the International Symposium on Cardiac Ion Channels and Effects of Taurine on the Heart (Seoul, Korea, 1992)

Proceedings of the Ninth Annual Symposium on New Drugs & Devices, October 27 and 28, 1988