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This book, written by the leaders in this young research area, describes the latest developments in allosterism for drug discovery.
This book identifies and elaborates the most recent and compelling strategies for antibiotic drug discovery with a primary focus on new targets, mechanisms and molecular entities.
This book considers the relationship between structure and function in G protein-coupled receptors (GPCRs) and the implications for drug design.
This is the first book to examine the future opportunities and challenges in the development of drugs which target kinases
Shows how different parts of the drug discovery process have developed, with particular emphasis on quantitative aspects and possible future progress.
This thorough and up-to-date insight into predictive technologies considers what is on the horizon for safety prediction in human health.
This exemplary book gives an up-to-date perspective on the role of metal ions in neurodegeneration.
Describes proteolytic enzymes and their biological function to aid drug discovery by detailing methods of production and assay of the enzymes.
This is the first comprehensive description of the discovery and therapeutic potential of polyamine drugs.
A volume that will provide a mechanism-based approach to understanding Chinese medicine for both Western and Eastern scientists.
New Tools to Interrogate Endocannabinoid Signalling comprehensively covers the innovative research into both natural and synthetic compounds. This timely volume will be a valuable resource to pharmaceutical researchers and medicinal chemists working in natural products and endocannabinoid drug discovery in academia and industry.
Antibody-drug conjugates are a promising areas of anticancer drug discovery, conveying several advantages, including the ability to select likely responders, efficient delivery of cytotoxic agents and reduced toxicity. This book describes payloads used to date and novel payloads that may be used clinically in the future.
Written by medicinal chemists and ADMET scientists with a combined experience of over 300 years this aid to discovering drugs provides detailed coverage on absorption, distribution, metabolism, excretion and toxicology issues associated with new drugs.
This book, aimed at academics, industrialists and post-graduates, documents the latest research into computer aided drug design.
This is the first book to pull together studies and reviews from cutting edge authors who work in the emerging and exciting field of multi-targeted drug discovery.
This is a wide scope and in-depth coverage of the state of the art and future directions in drug discovery for major psychiatric disorders.
An integrated review of the most recent trends in natural products drug discovery and key lead candidates that are outstanding for their chemistry and biology in novel drug development.
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