Books in the Handbook of Reagents for Organic Synthesis series

Reduction and oxidation processes are at the heart of almost all synthetic procedures and organic chemists are keen to have a huge portfolio of slick and modern catalytic reagents performing oxidations or reductions. This new volume is part of the Handbook for Reagents for Organic Synthesis series, making use of the leading reagent database e-EROS.

Recognising the critical need for bringing a handy reference work that deals with the most popular reagents in synthesis to the laboratory of practising organic chemists, the Editors of the acclaimed Encyclopedia of Reagents for Organic Synthesis (EROS) have selected the most important and useful reagents employed in contemporary organic synthesis.

Since its discovery in 1963 by R.B. Merrifield, solid-phase synthesis, or polymer-supported synthesis, has become an essential technique with its wide use in the synthesis of peptides and other oligomers.

The Synthesis of biopolymers and their conjugates is of ever increasing importance in bioorganic chemistry and chemical biology. As the need for such systems becomes ever more widespread, their synthesis is necessarily practiced in a broader spectrum of laboratories beyond the specialized ones that have traditionally concentrated in the area.

While a number of books describe the importance and application of different aspects of coupling reactions, this Handbook compiles all major catalyst components in use in the area, and is intended to guide the experimentalist and facilitate choice among the numerous reagents available for any one purpose.

Synthetic chemists, most particularly in the medicinal and pharmaceutical chemists, are often called upon to prepare compounds that contain Fluorine as a key structural feature. Fluorine-Containing Reagents provides an important source of information for the selection and handling of the right reagents.

One of four handbooks derived from the renowned Encyclopedia of Reagents for Organic Synthesis, this volume focuses on activating and protecting agents. It follows the same format as the Encyclopedia, including an introduction and an alphabetical arrangement of the reagents.

Over the last three decades the importance of organosilicon chemistry has greatly increased because it has opened a number of new synthetic strategies. Silicon reagents are usually low-cost, versatile and allow a wide range of reactions.