Books in the Imaging in Medical Diagnosis and Therapy series

Adaptive Radiation Therapy (ART) offers the promise of highly individualized radiation treatment for cancer patients through customized planning and delivery. This comprehensive book, the first focused on this evolving therapy, explores ways to optimize radiation plans. This includes the use of patient-specific 3D and 4D morphological and biological information to help define targets and individualize post-treatment assessment. It brings together world-class experts who discuss technologies for the delivery of treatments across various modalities. They also review clinical examples that demonstrate modern applications of ART for various cancers.

This book is a comprehensive survey of the field of medical imaging informatics. In addition to radiology, it also addresses other specialties such as pathology, cardiology, dermatology, and surgery, which have now adopted the use of digital images. The text discusses basic imaging informatics protocols, picture archiving and communication systems, and the electronic medical record. It also details key instrumentation and data mining technologies used in medical imaging informatics, as well as practical operational issues such as procurement, maintenance, teleradiology, and ethics.

This volume explains the biophysics and theory behind many MRI techniques and gives examples of how these techniques are applied in cancer diagnosis and treatment. The first section of the book presents basic cancer biology, theoretical aspects of NMR/MRI physics, and the hardware required to form MR images. The next three sections cover image processing and characterizing tissue properties using endogenous and exogenous contrast mechanisms. The book concludes with emerging areas of MR cancer characterization, including radiation therapy planning, molecular and cellular imaging, pH imaging, and hyperpolarized MR.

An up-to-date guide to using proton and carbon ion therapy in modern cancer treatment, this book offers a balanced and critical assessment of state-of-the-art technologies, major challenges, and the future outlook of the field. It covers the physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, and treatment delivery systems. The book also gives practical guidance on patient setup, target localization, and treatment planning for clinical proton and carbon ion therapy, offering detailed reports on the treatment of various cancers.

Reflecting recent advances in the field, this book provides the first detailed treatment of online interventional techniques for motion compensation radiotherapy. It explains how adaptive motion intervention is imaging-intensive and relies on near real-time image acquisition and processing. With a focus on the strategy of online motion compensation, the book discusses necessary motion detection methodology, repositioning methodology, and how to interpret and respond to target movement data in real time. It covers methods of detection and correction and then offers examples. It also gives attention to the distinct problems in dose planning and delivery posed by each adaptation technology.

This book explores the use of Monte Carlo methods for modeling various features of internal and external radiation sources. It addresses applications of the Monte Carlo particle transport simulation technique in radiation therapy, mainly focusing on external beam radiotherapy and brachytherapy. Along with presenting mathematical and technical aspects of the methods, the book discusses the modeling of medical linacs and other irradiation devices; issues specific to electron, photon, and proton ion beams and brachytherapy; and the optimization of treatment planning, radiation dosimetry, and quality assurance.

Detailing multi-modality image co-registration and radiobiology, this book discusses state-of-the-art strategies for patient simulation and immobilization, treatment planning, and dose calculation algorithms in stereotactic radiosurgery (SRS) and stereotactic radiotherapy (SRT). It presents a comprehensive treatment of the field¿s history, major technological developments, clinical status, and practical considerations. The three main sections of the book cover delivery systems, precision patient positioning and immobilization, and treatment planning and dosimetry. The final section gives an overview of clinical outcomes and future directions for the field.

This book gives readers an in-depth look into how big data is having an impact on the clinical care of cancer patients. Basic principles are covered early on, and clinical applications become the focus thereafter. A final section introduces emerging models for cancer prevention and detection.

Due to improvements in image quality and the reduced cost of advanced features, ultrasound imaging is playing a greater role in the diagnosis and image-guided intervention of a wide range of diseases. Designed for individuals working on diagnostic and therapeutic applications, this book highlights the latest advances in using ultrasound imaging in image-guided interventions and ultrasound-based therapy. It presents current and emerging techniques, identifies trends in the use of ultrasound imaging, and addresses technical and computational problems that need to be solved.

This comprehensive book provides a detailed introduction to plastic scintillation dosimetry and its use in the field of radiation dosimetry. Comprised of chapters authored by leading experts in the medical physics community, the text discusses a broad range of state-of-the-art technical implementations, from point source dosimetry scaling to 3D-volumetric and 4D-scintillation dosimetry. It addresses a wide scope of clinical applications, from machine quality assurance to small-field and in vivo dosimetry. It also examines related optical techniques, such as optically stimulated luminescence (OSL) or ¿erenkov luminescence.

This text provides coverage of PET and SPECT instrumentation and multimodality imaging. It takes an integrative approach, bridging the researcher and clinician¿s perspectives. It begins with an introduction to basic physics of PET and SPECT, followed by a section on detector technology. It addresses various aspects of producing quantitative images, such as techniques for image reconstruction, corrections to the data to produce quantitative images, and dynamic imaging. It also discusses instrumentation for multimodality imaging and technologies used in pre-clinical imaging using PET and SPECT.

Detailing multi-modality image co-registration and radiobiology, this book discusses state-of-the-art strategies for patient simulation and immobilization, treatment planning, and dose calculation algorithms in stereotactic radiosurgery (SRS) and stereotactic radiotherapy (SRT). It presents a comprehensive treatment of the field¿s history, major technological developments, clinical status, and practical considerations. The three main sections of the book cover delivery systems, precision patient positioning and immobilization, and treatment planning and dosimetry. The final section gives an overview of clinical outcomes and future directions for the field.