Books in the Neuroimmune Biology series

The book describes the mechanisms involved in the maintenance of neuroendocrine-immune interactions in ageing. The lack of this maintenance leads to the appearance of age-related diseases (cancer, infections, dementia) and subsequent disability.

Summarises the understanding of the Nervous, Endocrine and Immune systems with emphasis on shared mediators and receptors and functional interaction. This work contains basic information, theoretical considerations and clinical chapters. It also presents clinically relevant subjects such as: inflammation, asthma, and allergy.

Presents an account of the activities of the evolutionarily conserved molecules, cells and processes of the natural immune system. This work focuses on the relationship of the neuroendocrine system with natural immunity. It also reviews the effects of behaviour, aging, and exercise, and diet on natural immunity.

The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the immune system and provides experimental and clinical data to support the understanding in the field.

It is well recognized that the brain, and especially the hypothalamus, plays an important role in the regulation of immune reactions and inflammation. This book aims to review our current state of knowledge of this important field. It presents key historical findings and examines the reciprocal interactions between the brain and the immune system.

Presents an understanding on the presence and function of CNS cytokines and their receptors in a variety of central nervous system cells during health and disease. This work demonstrates the presence and synthesis of cytokines in brain cells, as well as their receptors on cell membranes in health and disease.

Neuropeptides released from activated nociceptive afferent nerves play a pivotal role in inflammatory reactions and pain. This book includes several chapters that deal with the therapeutic potential of a new class of putative pain relieving agents acting through TRPV1, the capsaicin/vanilloid receptor, a specific ion channel which transmits pain.