Books in the Neuroscience and Respiration series

Lung ventilation is driven by a complex neural regulatory network, and apart from conditions typically observed during a disease state, it is sensitive to functional dysregulation.

The book presents the latest advances in research into health effects of air pollution, with heavy motor vehicle traffic or cigarette smoke as the exemplar of pollution.

This book aims at unraveling the mechanisms and improving the treatment of pulmonary pathologies, ranging from such common conditions like influenza and related viral infections, functional lung dysfunction, to lung lesions and others.

The book presents current progress in clinical practice and research, particularly involving pulmonary diseases. Chapters tackle a variety of topics including a search for potential biomarkers of lung tumors, sleep disordered breathing, neurogenic lung dysfunction, community acquired and nosocomial respiratory infections developing in the chronically ill, mechanisms of hypoxia sensing, and the reasons for frequent visits to primary care facilities causing an ever increasing costs for caregivers and society. Identifying molecular markers expressed in tumors, rather than histological stratification of cancer type, forms a rapidly evolving basis of precision medicine, with the hope of a future development of targeted treatment. Creative ideas drive basic research that spurs innovations that, in turn, when translated into clinical applications, lay the foundation of breakthroughs, hopefully leading to increased longevity and better quality of life. This book is intended for healthcare professionals, particularly pulmonologists, primary care physicians, and other specialists involved in the management of patients.

The successful prophylaxis and treatment of ubiquitous respiratory infections is essential for the enhancement of public health. The chapters provide new insights into the biology of causative pathogens, tackle the epidemiological aspects, and present an update on diagnostics, prevention and therapy of infections.

Lung cancer and autoimmune diseases are complex entities in that they involve gene disturbance, gene polymorphism, and impaired gene repair mechanisms. The volume focuses on altered gene expression in tumor processes and in chronic autoimmune disorders.

Cardiorespiratory function is prominently affected by oxidative stress. Alterations in inflammatory cytokines and proteins as well as degradation of muscle proteins due to smoking, by far unrecognized, caused by oxidative stress also are presented.

The dynamics of body metabolism are changed in the disease process and interact with physical activity. The chapters aim to investigate various interacting components converging on metabolic changes in lung and muscle tissues taking into consideration the drug effects.

The research sheds new light on the immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) and the cells expressing Siglec receptors as being key players in the immune system responsiveness to antigens and thus in lung tissue damage of chronic inflammation.

This volume provides a modern look on the age-old influenza infection and the preventive role of anti-influenza shots. The chapters cover vaccination strategies in various age-groups of people and provide the extensive amount of knowledge on the immune response to influenza vaccination in a spectrum of disease conditions.

Pulmonary disorders significantly contribute to the current level of disease burden. This book highlights the issues involved with diagnosing and managing various pulmonary conditions such as chronic obstructive pulmonary disorders, respiratory tract infections, including those developing as a sequel of antibiotic treatment, and others.

The book blends basic and clinical research on respiratory carcinogensis. The focus is on the search for novel molecular markers, derived from easily accessible tissues in clinical settings, such as the serum or bronchoalveolar lavage fluid, which could help diagnose cancer at an early stage and have a prognostic therapeutic value.

The book provides reader-friendly information on aspects of pulmonary infections, including comprehensive accounts of bacterial and viral diseases, therapeutic approaches, molecular and classical culture-related techniques of diagnosis and explaining the basic cell biological mechanism.

The book focuses on the contagion nature of respiratory ailments, the ways a pulmonary disease is spread. The book will be of interest to clinicians, researchers, health care providers, and other health care professionals, particularly those dealing with contagious diseases.

Medical experts present their lines of scientific investigations on how to contain the disease, care for patients, and use preventive measures, with a focus on pulmonary-related disorders.

Pulmonary diseases are the major cause of human morbidity, taxing the health care system due to disease prevalence, chronicity, and social and fiscal costs. Inflammation also is an essential component of non-communicable lung diseases, including asthma and respiratory allergies, and smoking-related or granulomatous diseases.

The impairment of lung function caused by environmental exposure to pollutants and toxicants is a rising health problem, particularly in highly industrialized parts of the world.

The book presents the latest advances in research into health effects of air pollution, with heavy motor vehicle traffic or cigarette smoke as the exemplar of pollution.

Population-based clinical, epidemiological, and multicenter investigations are presented to provide a comprehensive update on prevalent respiratory problems; Chapters are relevant to the broad readership as they examine health care quality, effectiveness of therapeutic strategies, the patient quality of life, and other relevant health issues.

This book presents a range of research and clinical contributions, including observational studies, practical treatment examples, diagnostic test assessment, biomarkers, and systematic reviews.

Good health and medical care in childhood and adolescence are essential for the ability to neutralize health threats later in life and to extend longevity.

Cognitive changes, related to dysregulated cellular mechanisms in cancer cells, as yet unchartered area of research, also are tackled. A better understanding of the molecular and cellular biology of lung cancer is the key source of breakthroughs in the diagnosis and prognosis, and finding more effective therapies that target specific mutations.

The book blends basic and clinical research on respiratory carcinogensis. The focus is on the search for novel molecular markers, derived from easily accessible tissues in clinical settings, such as the serum or bronchoalveolar lavage fluid, which could help diagnose cancer at an early stage and have a prognostic therapeutic value.

This book runs the gamut of chapters devoted to chronic cough-related conditions in children and adults, health care quality and safety, environmental pollution health effects, efficiency of therapeutic approaches and a mutual dependence of respiratory and non-respiratory illnesses.

Diseases of the respiratory system often cause multisystem dysfunction and morbidity.

The book discusses new concepts and findings in the field of pulmonary function. Pulmonary function goes far beyond spirometry. Chapters contribute to the latest thinking on molecular mechanisms underpinning pulmonary function, on patient care and attempt to keep up-to-date with current clinical and research progress.

The chapters of this book deal with the preventable drivers of poor respiratory health, the role of health information technology, the improvement in health care delivery and the integration of respiratory health and behavioral health services.

The book presents the latest developments in clinical medicine, particularly involved with pulmonary care and diseases.

This volume provides a modern look on the age-old influenza infection and the preventive role of anti-influenza shots. The chapters cover vaccination strategies in various age-groups of people and provide the extensive amount of knowledge on the immune response to influenza vaccination in a spectrum of disease conditions.

The book provides reader-friendly information on aspects of pulmonary infections, including comprehensive accounts of bacterial and viral diseases, therapeutic approaches, molecular and classical culture-related techniques of diagnosis and explaining the basic cell biological mechanism.