Books in the Pharmacochemistry Library series

Presents an account of the chemotherapy of parasitic diseases, human and veterinary. This book provides an overview of parasitic diseases. It is divided into two parts: antihelminthic drugs, and antiprotozoal drugs. It deals with one chemical class of compounds and describe their origin, structure-activity relationship, mode of action, and more.

Stable isotope techniques offer advantages in safety, sensitivity, specificity, and economy for various types of pharmaceutical investigations. This book includes comprehensive reviews of various applications of stable isotopes and the background material necessary to understand the application.

Comprises the text of invited lectures presented at the 11th Noordwijkerhout-Camerino Symposium Trends in Drug Research, held in Noordwijkerhout, The Netherlands, from 11-15 May 1997.

Vaso-occlusive disorders including unstable angina, myocardial infarction, transient ischemic attacks, stroke and peripheral artery disease remain the major sources of morbidity and mortality in western civilization. This volume provides an assessment of ongoing clinical trials, clinically established agents, and developments in this field.

In the early eighties when the H3 receptor was identified, many thought that an H3 ligand, an agonist or an antagonist, would become available as a therapeutic agent. This has not occurred. This book presents the state of affairs with regards to the medicinal chemistry and pharmacology of the H3 receptor.