Books in the Principles of Medical Biology series

Dramatic advances in biological psychiatry have attested to the staying power of the experimental method. Those who made this revolution in knowledge happen are a breed of investigators availing themselves of the tools of molecular biology, pharmacology, genetics, and perhaps, above all, the technology of neuroimaging.

An introduction to the study of cell chemistry and physiology. This volume is not intended to be encyclopedic in nature but rather a general survey of the subject with an emphasis on those topics that are useful to an understanding of cell biology, and those that are important in the teaching of modern medicine.

Illustrates the extent to which the traditional distinction between biochemical and physiological processes is being obliterated by molecular biology. This work looks at the revolution in cell and molecular biology that is leading to core knowledge that provides an outline of the integrative and reductionist approach.

Tells how the traditional boundaries of cell chemistry and physiology are being erased by molecular biology. This book deals with the chemistry of actin and myosin and contains chapters on cell motility, ATP synthesis in muscle, and contraction in smooth and skeletal muscle.

A sequel in the series "Principles of Medical Biology", whose general aim is to be the integration of human biology and molecular cell biology into modern molecular medicine. This volume takes into account the close dependence of progress in the medical sciences on bioinformatics or more precisely, computational biology and the Internet.

Divided in two parts, this volume first includes chapters on cellular organelles and also those relating to organelle disorders. The second part is concerned with the extracellular matrix. It sets out to show that a vast body of knowledge of the extracellular matrix is available to us such as: the integrin family of cell adhesion receptors.

Consisting of chapters on the nature of membrane transport systems, this work includes co-transport systems namely, Na+ -K+ -2CI-, KCI, -HCO-3, as well as CI- -HCO-3 exchange and K+ and CI- movements through channels. It also reveals that calometric measurements are useful in studies of clinical and toxicological problems.

Focuses on evolutionary biology. Divided in to two parts, this title deals with the structure and dynamics of RNA, DNA, and protein, and with the origins and cellular basis of life.

Presents a synopsis of the knowledge on the structure, organisation, and function of cellular organelles with an emphasis on the examination of important but unsolved problems, and the directions in which molecular and cell biology are moving. This volume includes chapters on the subject of organelles, and organelle disorders.

It should not come as too much of a surprise that biological membranes are considerably more complex than lipid bilayers. This has been made clear by the fluid-mosaic model which considers the cell membrane as a two-dimensional solution of a mosaic of integral membrane proteins and glycoproteins firmly embedded in a fluid lipid bilayer matrix.

The tools of molecular biology have revolutionised our understanding of gene structure and function and changed the teaching of genetics in a fundamental way. This book aims to provide an account of the new science of molecular genetics. It places considerable emphasis on major technical advances, expounding numerous ideas and phenomena.