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Quadruplex Nucleic Acids discusses all aspects of the fundamentals of quadruplex structures, including their structure in solution and the crystalline state, the kinetics of quadruplex folding, and the role of cations in structure and stability.
A collection of methods to determine and analyse the 3-D structure of biomolecules. These methods have been enhanced to improve the speed and quality of drug discovery.
Written by leaders in the field, this volume describes the preparation and application of DNA-conjugates. Several have been used as sensors whilst others link reporter groups such as proteins or fluorophores to RNA or DNA for detection, single molecule studies, and increasing the sensitivity of PCR.
This two volume set describes innovations in biomolecular modeling and simulation, in both the algorithmic and application fronts.
This two volume set describes innovations in biomolecular modeling and simulation, in both the algorithmic and application fronts.
This exceptional monograph, by experts in structural biology and virology, is for biomedical scientists involved in basic and applied research.
With contributions from experts in the field, this book provides a comprehensive overview of the oxidative folding of cysteine-rich peptides.
This book highlights recent advances in the way computer simulation can be applied to the field of membranes and membrane proteins.
Written by leading experts, this book provides a comprehensive overview of protein-carbohydrate interactions for researchers.
This book provides a complete overview of current techniques to identify ligands, characterise their binding sites and understand binding mechanisms. Suitable for biomolecular scientists at graduate or post-doctoral level in academia and industry. Biologists and chemists will also find it a useful introduction to the techniques available.
This up-to-date summary of natural product chemistry in drug discovery will appeal to scientists, professionals, postgraduates and industrial chemists.
This book discusses diverse modes of binding of antibiotics and drugs to DNA, emphasising matters that are important or promising for cancer treatment.
This unique book covers all the modern approaches and the many advances experienced in the field of protein folding and aggregation during the last 10 years.
This insightful book represents the experience and understanding of the global experts in the field and spotlights both the structural and medicinal chemistry aspects of drug design. The need to 'encode' the physiological factors of pharmacology, a key area, is explored.
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