Books in the Series in Computational Biophysics series

This book presents modern biomolecular computational techniques that address protein flexibility/dynamics at all levels of theory. It shows how these advanced methods provide insights into dynamic aspects of biochemical processes. The book covers a wide spectrum of dynamics, from electronic structure-based to coarse-grained techniques via multiscaling at different levels. It describes the methods and results of enzyme catalysis, examines computational techniques to tackle biological problems involving intrinsically disordered proteins (IDPs), and discusses computational issues related to experimental characterization of IDPs.

This timely summary reflects the recent advances in bridging novel algorithms and high performance computing with characterization of important biological processes, such as folding dynamics of key proteins.

This book reflects on the tremendous impact of computational modeling, focusing on coarse-grained simulations for biomolecules, such as proteins and nucleic acids, for which systems may be too large and the processes too slow for atomistic or quantum simulations.

This timely summary reflects the recent advances in bridging novel algorithms and high performance computing with characterization of important biological processes, such as folding dynamics of key proteins.