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An issue that reviews the major areas of clinical interest in Dental Sleep - Sleep Bruxism; Oral Evaluation and Screening by the Dentist; the Neurologic Basis of Sleep Breathing Disorders; Sleep and Orofacial Pain; Cone Beam Imaging of the Airway; and, The Cervical Spine - Considerations and Treatment for Sleep Disordered Breathing.
Focuses on both general and specific aspects of neonatal and pediatric clinical pharmacology including ethics, pharmacogenomics, metabolomics, adverse drug reactions, pain medication, pulmonary hypertension and several other hot topics.
This issue of Endocrinology and Metabolism Clinics provides a comprehensive review of osteoporosis written by the world's leading experts. Topics include new mechanistic insights into pathophysiology; bisphosphonates; combination therapy; atypical fractures; non-BP anti resorbers; anabolic therapies; calcium; the impact of Vitamin D on bones; extraskeletal effects of Vitamin D; glucocorticoid osteoporosis; relation to anorexia nervosa, coeliac disease, and diabetes; and male osteoporosis.
To ensure the best possible clinical outcomes for arthritis patients, it is essential that they be seen early and treated appropriately at the earliest opportunity. Early therapy has proven much more effective than that given late. This issue of Rheumatic Disease Clinics of North America brings the rheumatologist up to date on the latest treatments and interventions in evolving arthritis and established early arthritis. Topics covered include early rheumatoid arthritis, psoriatic arthritis, undifferentiated arthritis, oligoarthritis, osteoarthritis, and others. Imaging modalities are addressed as well as various contemporary treatments including biologics.
This issue on Sleep Electroencephalography (EEG) gives an overview of Electrophysiological readings in sleep with such articles as "e;The Nuts and Bolts of EEG and "e;How the Sleep/Wake EEG Changes Across the Lifespan. Identifying abnormal EEG activity and patterns in the Electroencephalographic readings is also discussed. The issue then further focuses in on Seizures and the EEG; specifically, how EEG can be used to diagnosis and identify seizure disorders and differentiate seizures from other paroxysmal nocturnal events, and to diagnose other primary sleep disorders in people with epilepsy.
This issue features internationally renowned experts who have provided their expertise on a variety of topics related to the importance of vitamin D. It was not until feed back loops were identified between Vitamin D production and parathyroid hormone, phosphate that it earned its place as a true endocrine hormone. Current social and economic conditions have brought it back into the limelight with outbreaks of rickets and osteomalacia even in developed countries. However its complex regulation, together with the identification and characterization of the vitamin D receptor and its role in influencing multiple genetic pathways and function has heralded a new era highlighting its importance in health and disease. This includes its role in auto immune diseases such as multiple sclerosis, diabetes mellitus, cancer especially breast and prostate, skin, neurological and cognitive disorders and infectious diseases such as tuberculosis. We now know that adequate levels of vitamin D it is important in preventing falls and fracture. The need for supplementation and the amount recommended has also changed considerably from what we previously considered sufficient. The ongoing development of selective active analogs of vitamin D targeted to specific organs and function leads to the exciting possibility of improving outcomes of diseases associated with vitamin D regulation.
This issue guides the primary care physician through the prental care of their patient with topics that include: Preconception Care, Antepartum Care, Nutrition, Genetic Screening, First Trimester Complications, Management of Gestational Diabetes, Third Trimester Complications, Electronic Fetal Monitoring, Complications of Labor and Delivery, Operative Delivery, Postpartum Hemorrhage, and Alternative Approaches to Maternal Care.
A very hot topic at the 2010 AASLD meeting, hepatic encephalopathy is being brought to the Clinics in Liver Disease for the very first time by top experts, Dr. Mullen and Dr. Prakash. Authors have written articles that fully discuss the clinical aspects of hepatic encephalopathy (HE). Articles presented include History, Nomenclature and Classification; Theories involved in the pathogenesis of HE; Clinical Assessment and utility of clinical scales for semi-quantification of Overt HE; Assessment of Minimal HE( with emphasis on computerized psychometric tests); Brain Imaging and HE; Management of Overt HE; Management of Minimal HE; Nutritional Interventions for HE; TIPS and HE; Liver Transplantation and Reversibility of HE; Minimal HE and Driving; and HE and Quality of Life.
This issue brings the rheumatologist on the current thinking on treatment of Systemic Lupus Erythematosus, with an eye to the future. Topics covered include B cell biology and related therapies; glutamate receptor biology and its clinical significance in neuropsychiatric SLE; platelet C4d and vascular complications; biomarkers in lupus nephritis; endothelial function and its implications for cardiovascular and renal disease in SLE; changing worldwide epidemiology of SLE and its relationship to environmental, ethnic, and other sociodemographic factors; work loss, disability, quality of life, and compliance in SLE; pediatric lupus; metabolic syndrome and related endocrine abnormalities; the significance of interferon and the consequences of anti-interferon in SLE; and cutaneous lupus and the CLASI instrument.
This issue examines what is a healthy aging brain and covers preventive measures for succesful cognitive aging. Topics covered include: A road map to healthy aging brain; Cardiovascular risk factors, cerebrovascular disease burden and healthy aging brain; Healthy aging brain: Impact of head injury, alcohol and environmental toxins; Healthy aging brain: What has sleep go to do with it?; Endocrine aspects of healthy aging brain; Healthy aging brain: Role of exercise and physically active lifestyle; Healthy aging brain: Role of nutrition and nutritional supplements; Healthy aging brain: Role of cognitive reserve, cognitive stimulation and cognitive exercises; Healthy aging brain: Impact of positive and negative emotions; Dementia risk predictor. Are we there yet?; Potential future neuroprotective therapies for neurodegenerative disorders and stroke; Healthy aging brain: Importance of promoting resilience and creativity.
This issue of Endocrinology and Metabolism Clinics of North America provides the endocrinologist with essential updates on treatment of type 1 diabetes, with an eye toward future trends and developments. The Guest Editors brought together a remarkable group of notable authors, such as Paul Robertson, President of the National Diabetes Association. Topics covered include epidemiology; economics; contemporary management; inpatient management; update on insulin pumps and continuous glucose monitoring systems; update on studies aimed at interdicting and preventing type 1 diabetes; advances in the prediction, natural history, and mechanisms leading to type 1 diabetes; complications; hypoglycemia in type 1 diabetes; new lessons from animal models; the role of the gut in the genesis of type 1 diabetes and other autoimmune diseases; and an update on transplantation for reversing type 1 diabetes.
This issue of Hematology/Oncology Clinics, guest edited by Dr. Jennifer R. Brown?, will focus on Chronic Lymphocytic Leukemia. This issue is one of six selected each year by our series consulting editors, Dr. George P. Canellos and Dr. Edward J. Benz. Topics discussed in this issue will include: Chronic Lymphocytic Leukemia: Do We Know the Cell of Origin Yet?; Significance of BCR Stereotypy; Prognostic and Predictive Implications of Cytogenetics and Genomics; Role of Epigenetics in Chronic Lymphocytic Leukemia; Genomics of Resistance to Targeted Therapies; First Line Therapy for Chronic Lymphocytic Leukemia; The Ongoing Unmet Needs in Chronic Lymphocytic Leukemia Therapy; BTK Inhibitors; Minimal Residual Disease; Should Undetectable MRD Be the Goal of Chronic Lymphocytic Leukemia Therapy?; Management of Chronic Lymphocytic Leukemia after Progression on BTK Inhibitors; Role of PI3K Inhibitors in Chronic Lymphocytic Leukemia; Can We Restore the Immunodeficiency of Chronic Lymphocytic Leukemia?; and Immune Therapy for Chronic Lymphocytic Leukemia
In collaboration with Consulting Editor, Dr. Norman Gitlin, Dr. Tarek Hassanein has assembled top experts in hepatology to bring current information on the topic of Hepatitis B Virus. The issue provides the most current information on the prevention and care of infected patients. Specific articles are devoted to the following topics: Global perspective on HBV infections in the era of effective vaccines; Understanding the natural history of HBV infection and the new definitions of cure and the endpoints of clinical trials; HBV/HCV coinfection in the era of HCV-DAAs; Antiretroviral effects on HBV/HIV coinfection and the natural history of liver disease; Impact of HBV infection on HCC and liver transplantation; HBV in pregnant women and their infants; WHO guidelines for prevention, care and treatment of individuals infected with HBV: A US perspective; Reconciling the difference between the major HBV treatment guidelines: AASLD, EASL, APASL; HBV/HDV coinfection: A challenge for therapeutics; and The effects of hepatic steatosis on the natural history of HBV infection. Readers will come away with the current information they need to manage patient outcomes.
This issue of Interventional Cardiology Clinics, guest edited by Dr. Susheel Kodali, will cover several key topics of importance surrounding Transcatheter Aortic Valve Replacement. The series is overseen by the Editor-in-Chief, Dr. Matthew Price of Scripps Translational Science Center. Subjects discussed in the issue include: Embolic protection during TAVR; Impact of Atrial Fibrillation on Outcomes Following TAVR; When to Intervene; Innovations in Transcatheter Valve Technology; Paravalvular Regurgitation; Challenges and Pitfalls of Bicuspid Valves; Tips and Tricks for Valve in Valve, and When to Choose Surgery in the Era of TAVR, among others.
Patients in psychiatry, or their parents, experiment with alternative methods and practices; psychiatrists, in search of scientifically-based discussion and evidence of use for daily practice, find that information in this issue of Child and Adolescent Psychiatric Clinics. Readers will find clinically focused information in the major categories of Selected Treatments, Selected Disorders, and Perspectives on Clinical Complementary and Alternative Therapies. Pharmacologic and non-pharmacologic treatments are discussed for ADHD, Mood disorders, Autism, Learning and Cognitive disorders, and Neurologic disturbances, such as sleep, traumatic brain injury, headache, etc. EEG and Neurofeedback, Meditation and Movement Therapies, Music Therapy, Massage, Acupuncture, and other body-based therapies are presented. Evidence for minerals, vitamins, and herbs is discussed, and Ethical and Legal issues for the Psychiatrist are presented. Guest Editors Deborah Simkin and Charles Popper, with decades of experience in working with complementary therapies, lead this issue.
Cervical Cancer screening, which includes the PAP test and HPV testing is an essential part of a woman's routine healthcare. This issue of the Ob/Gyn Clinics covers colposcopy and screening for women at all stages of life, along with the HPV vaccine, treatment options, and what is on the horizon regarding ever-changing screening methods.
This issue of Cardiac Electrophysiology Clinics covers arrhythmias in athletes, which can be a cause of morbidity and mortality. Expert authors review the most current information available about management of ventricular arrhythmias, atrial fibrillation, bradyarrhythmias, syncope and other conditions. Preparticipation screening, defibrillator use, and prevention are also discussed. Keep up-to-the-minute with the latest developments in this important aspect of cardiac electrophysiology practice.
This issue of Clinics in Chest Medicine is Guest Edited by Kristina Crothers, MD from the University of Washington and will focus on HIV and Respiratory Disease. Article topics include Abnormalities in Host Defense, Antiretroviral Therapy and Lung Immunology, HIV associated Pneumonia, HIV associated Tuberculosis, HIV associated lung malignancies, and HIV associated COPD.
This issue of Immunology and Allergy Clinics provides a comprehensive review of the current state of biomarkers and their role in the asthma diagnostic and therapeutic algorithm.Since the last issue on Biomarkers, which published in 2007, significant research directly targeted at biomarker development and clinical trials with new biologics, using biomarkers such as exhaled nitric oxide, sputum and tissue eosinophilia as endpoints, has occurred.
This issue of Clinics in Geriatric Medicine focuses on the pharmacological, non-pharmacological, and device therapies in the medical management of cardiac rhythm disorders in the elderly population. It also reviews the epidemiology of arrhythmias and conduction disorders in older adults, atrial fibrillation and atrial flutter: stroke prevention, bradyarrhythmias and conduction disorders, and comorbidities, quality of life, and end-of-life issues in older patients with heart rhythm disorders.
The Guest Editors have assembled international experts in rheumatology to present an update to pediatricians. The basics are covered, including an article on the principles of inflammation in the child and one on the approach to the child with joint inflammation. From there, specifics are presented in the following articles: Laboratory Testing in Rheumatology; Rheumatologic Emergencies in newborns, children and adolescents; Juvenile Idiopathic Arthritis; Macrophage Activation Syndrome; Systemic Lupus Erythematosus; Idiopathic Inflammatory Myopathies in Childhood; Scleroderma; Vasculitis; Kawasaki disease; Autoinflammatory diseases; Approach to the patient with non-inflammatory musculoskeletal pain; and Immune deficiency diseases with rheumatic manifestations.
The Guest Editors have assembled expert authors to cover the full clinical span of the topic autism and autism spectrum disorders. An historical perspective of the evolution of the disorder opens the issue. Next, comprehensive coverage is given to an article on the definitions, diagnostic criteria, and clinical features of autism spectrum disorders. Other articles in the issue cover the relevant topics like epidemiology, genetic syndromes and genetic testing, early diagnosis and diagnostic evaluation, and neuroimaging and neurochemistry of autism. Authors also present information on tsocial skills for the autistic child, behavioral interventions, and transitioning the autistic child into adulthood, to name a few. This issue should be very well received by pediatricians.
Biologic response modifiers (BRMs) are substances that stimulate the body's response to infection and disease. The body naturally produces small amounts of these substances. Scientists can produce some of them in the laboratory in large amounts for use in treating infections and other diseases. This issue reviews the use of BRMs to treat infectious diseases as well as the infectious complications of BRMs used to treat non-infectious diseases. Articles on vaccines, antibodies, interferon, and other substances are included.
This issue of Pediatric Clinics, guest edited by Drs. Dilip Patel and Donald Greydanus, examines the topic of Adolescents and Sports. Authorities in the field have come together to pen articles on Pre-participation evaluation, Cardiovascular evaluation of young athletes, Medical conditions and sport participation, Management of the adolescent athlete with type 1 diabetes mellitus, Musculoskeletal conditions and sports participation, Stress fractures: Diagnosis and management, Computer-based neuropsychological evaluation of concussion, The female athlete, Doping: From drugs and supplements to genetics, Analgesics and anti-inflammatory medications in sports, Nutritional considerations for adolescent athletes, Resistance training guidelines for adolescents, Application of osteopathic manual medicine to treat sports injuries, and Physically and cognitively challenged athletes.
This issue of Clinics in Laboratory Medicine, Guest Edited by Dr. Anand S. Dighe, will focus on Clinical Decision Support, including tools, strategies, and emerging technologies. This issue is one of four issues selected per year by the series Consulting Editor, Milenko Jovan Tanasijevic. Topics include, but are not limited to, The Laboratory's Role in Clinical Decision Support, Integrating Decision Support into a Utilization Management Program, Decision Support Tools within the Electronic Health Record, Decision Support to Enhance Automated Testing and Laboratory Workflow, Laboratory-based CDS programs, Decision Support in Blood Banking, Decision Support in Molecular Pathology, A Computational Perspective on Decision Support, Emerging Decision Support Techniques, Decision Support and Patient Safety, Decision Support from a Reference laboratory perspective, and Training Aspects of Laboratory Based Decision Support.
This issue of Hematology/Oncology Clinics, Guest Edited by Drs. Rachael Grace and Russell E. Ware, will focus on Pediatric Hematology. This issue is one of six selected for the year by the series Consulting Editors, George P. Canellos and H. Franklin Bunn. Topics include, but are not limited to, Rare Congenital Hemolytic Anemias, Sickle Cell, Thalassemia, Neutropenia and rare leukocyte disorders in children, Primary and Secondary Immune cytopenias, Disorders of Iron overload, Disorders of Iron metabolism, Approach to Hemophilia in a Changing Treatment Landscape, Von Willebrand disease, Inherited platelet disorders, Thrombosis, Diagnostic evaluation and medical approach to complications and treatment of vascular anomalies, New approaches and trials in Transfusion Medicine, and Updates in Neonatal Hematology.
This issue of Psychiatric Clinics, guest edited by Drs. Howard Liu and Donald Hilty, will take a unique approach to examining Professional Development for those practicing in the field of Psychiatry. Under the guidance of series consulting editor Dr. Harsh Trivedi, Drs. Liu and Hilty will explore development issues that might emerge for practicing psychiatrists over the course of their careers. Topics covered in this volume will include: Defining Professional Development in Medicine, Psychiatry & Allied Fields; Developmental Approaches to Professional Development; Developing Clinical Skills; Professional Development in Academia; Model Programs in Lifelong Learning for Professional Development; The Role of Mentoring and Coaching; Career Transitions; Advanced Leadership Training; Contributing to Culture and Diversity of Leadership; Wellness, Work/Life Integration, Burnout & Resilience; and the Role of Technology in Professional Development.
This issue of Immunology and Allergy Clinics, guest edited by Drs. Flavia Hoyte and Rohit Katial, is devoted to Biomarkers in Allergy and Asthma. Articles in this issue include: Exhaled Nitric Oxide; Biomarkers in Exhaled Breath Condensate (EBC); Role of Eosinophils in Asthma; Bronchoprovocation Testing in Asthma; Periostin and DPP4; Role of Neutrophils in Asthma; Urinary LTE4; Biomarkers in Nasal Polyps; IgE as a Biomarker in Asthma; Genetics of Asthma; and Biomarker-directed Therapies for Asthma.
This issue of Heart Failure Clinics--edited by Drs. Giuseppe Limongelli, Sharlene Day, and Perry Elliott--will cover Clinical and Molecular Aspects of Cardiomyopathies: On the Road from Gene to Therapy. Topics include, but are not limited to, Epidemiology and Clinical aspects of Genetic Cardiomyopathies, Existing and New therapies, Gene editing and gene-based therapeutics, Controversies surrounding exercise in genetic cardiomyopathies, Genetic infiltrative cardiomyopathies, LV Noncompaction, Clinical presentation and natural history of hypertrophic cardiomyopathy in Rasopathies, and Moelcular basis and new treatments of cardiac diseases in Rasopathies.