Books in the The Clinics: Internal Medicine series

This issue will provide a current update on diagnosis, treatment, and management of children with being hematological disorders. Dr. Callaghan has put together a comprehensive issue with clinical reviews written by top experts in the field. Articles are devoted to the following topics: Hemophilia; Sickle cell acute chest; Sickle cell drugs; Sickle cell gene therapy; Sickle cell menses and pain; Pediatric DVT; Atypical HUS; von Willebrand Disease; Female bleeding; Functional platelet disorders; Hemolytic anemia; Advocacy in hematology; ITP; and Acquired aplastic anemia. Readers will come away with the current clinical information they need to improve clinical outcomes.

This issue of Physician Assistant Clinics, guest edited by Laura A. Kirk, MSPAS, PA-C, is devoted to Otolaryngology. Articles in this issue include: Hyperparathyroidism: Workup and Treatment; "Sinus" Headaches: Sinusitis vs. Migraine; Sudden Sensorineural Hearing Loss; ENT Manifestations of Sarcoidosis; Pediatric Otitis Media; Evaluation and Management of Adult Neck Masses; Vestibular Migraine; Pediatric Sleep Disordered Breathing; Benign Paroxysmal Positional Vertigo (BPPV); Infectious and Inflammatory Salivary Disease; Evaluation and Management of Pediatric Neck Masses: An Otolaryngology Perspective; and Indications for Cochlear Implantation.

This issue of Anesthesiology Clinics focuses on Quality Improvement and Implementation Science, with topics including: Applying implementation science principles to perioperative care; Emergency checklists in perioperative care; Human factors applied to perioperative process improvement; Handoffs in perioperative care; Use of simulation in performance improvement; Developing capacity to do improvement science work; Developing multicenter registries to advance quality science; Rethinking clinical workflow; data-driven quality improvement; and Scaling quality improvement at the health system level.

This issue of Endocrinology and Metabolism Clinics, guest edited by Dr. Michael Mingzhao Xing, is dedicated to Thyroid Cancer. Topics include, but are not limited to, Current Histological Classification of Thyroid Cancer, Molecular Pathogenesis and Mechanisms of Thyroid Cancer, Clinical Diagnostic Evaluation of Thyroid Nodules, Molecular Diagnostic Evaluation of Thyroid Nodules, Clinical Risk Stratification of Differentiated Thyroid Cancer, Molecular Risk Stratification of Differentiated Thyroid Cancer, Conventional Thyroidectomy in the Treatment of Primary Thyroid Cancer, Neck Dissection in the Surgical Treatment of Thyroid Cancer, Conventional Robotic Endoscopic Thyroidectomy for Thyroid Cancer, Transoral Endoscopic Thyroidectomy for Thyroid Cancer, Conventional Radioiodine Therapy for Differentiated Thyroid Cancer, Re-differentiation of Radioiodine-refractory Thyroid Cancer for Radioiodine Treatment, Management of Papillary Thyroid Microcarcinoma, Conservative Surveillance Management of Low-risk Papillary Thyroid Microcarcinoma, Thyroid-stimulating Hormone Suppression Therapy in Differentiated Thyroid Cancer, Diagnostic Imaging Testing in the Surveillance of Thyroid Cancer Recurrence, Novel Drug Treatments of Progressive Radioiodine-refractory Differentiated Thyroid Cancer, Management of Anaplastic Thyroid Cancer, and Management of Medullary Thyroid cancer.

This issue of Clinics in Geriatric Medicine, guest edited by Drs. Michael Malone and Kevin Biese, is devoted to Care for the Older Adult in the Emergency Department. Articles in this outstanding issue include: Approach to the Older Patient in the Emergency Department; Ten Best Practices for Older Adults in the Emergency Department; Delirium and Dementia; Falls and Geriatric Trauma; Older Adults in the Emergency Department with Frailty; Communication Strategies to Better Care for Older Individuals in the Emergency Department; Systems-based Practice to Improve Care Within and Beyond the Emergency Department; Common Medication Management Approaches for Older Adults in the Emergency Department; Elder Abuse and Neglect; Care of those with end-of-life needs / Advanced illnesses in the Emergency Department; Behavioral Health Needs of Older Adults in the Emergency Department; and Pain Management Strategies for Older Adults.

This issue of Primary Care: Clinics in Office Practice, guest edited by Dr. Diane M. Harper, is devoted to Women''s Health. Articles in this issue include: Social Constructs of How Women View and Obtain Their Healthcare; Becoming Reproductive; Family Planning and Contraception; Termination of Pregnancy; Female Athlete Triad; Menopause; Bone Health in Women; Cancers in Women; Cancer Survivor Health Needs for Women; Women''s Health and the Military; Transgendered Women: Female to Male and Male to Female; Plastic Surgery for Women; Integrative Health for Women; Geriatric Medicine and Palliative Care for Women; and Medication Assisted Treatment (MAT) Considerations for Women with Opiate Addiction Disorders.

This issue of Cardiology Clinics, edited by Dr. Andrew M. McCoy, will focus on Resuscitation. Topics include, but are not limited to Improving survival in your community, Compression only CPR, Dispatch, CRP quality issues, Drugs in OHCA, Mechanical CPR, DSeD, Nuances of Airway Management in OHCA, refractory/recurrent VF, future of OHCA care, and more.

This issue of Emergency Medicine Clinics focuses on Hematology and Oncology Emergencies, with topics including: Cardiovascular toxicities of cancer therapies; The latest cancer agents and their complications; Infections in the cancer patient; Pediatric oncologic emergencies; Rapid fire oncologic emergencies; Rapid fire hypercalcemia; Rapid fire sickle cell disease; Rapid fire SVC Syndrome; The Cancer ED; EM Oncology Fellowship; Anticoagulation Reversal; and Rapid Fire Blast Crisis/Hyperviscosity.

This issue of Hematology/Oncology Clinics, edited by Dr. Colin A. Sieff, will focus on Bone Marrow Failure. Topics include, but are not limited to, Acquired and Inherited Bone Marrow Failure; Kickapoo Joy Juice and Somatic Mutations in the Pathogenesis of AA; Somatic Mutations in Aplastic Anemia; Recent Advances and Long-term Results of Medical Treatment of AA; Upfront Matched Unrelated Donor Transplantation in AA; Significance of Clonal Mutations in the Diagnosis and Management of Myelodysplastic Syndrome; Alternate (Haploidental) Donor Transplantation in AA; Management of Diamond Blackfan Anemia and Prospects for Novel Treatment; MDS, AML and Cancer Surveillance in Fanconi Anemia; Diagnosis, Treatment  and Molecular Pathology of Shwachman Diamond Syndrome; Clinical Implications of Clonal Hematopoiesis in Dyskeratosis congenita; and Germline GATA2 Mutations and Bone Marrow Failure.

This issue of Immunology and Allergy Clinics, guest edited by Mariana C. Castells, MD, is devoted to Mastocytosis. Articles in this issue include: New Insight into Clonal Mast Cell Disorders Including Mastocytosis; Cutaneous Mastocytosis in Adults and Children: New Classification and Prognostic Factors; Hymenoptera Anaphylaxis as a Clonal Mast Cell Disorder; Non Clonal Mast Cell Activation Syndrome:  A growing body of evidence; Familial Tryptasemia Syndromes: Genotyping and Symptoms; POTS and EDS: Entities Associated to Mast Cell Activation; KIT Mutations: New Insight and Diagnostic Value; Patients'' Perceptions in Mast Cell Activation Disorders; Mast Cell Mediators of Significance in Clinical Practice; Tyrosine Kinase Inhibition in Mast Cell Activation Disorders; Gastrointestinal Involvement in Mast Cell Activation Disorders; Bone Marrow Expression of Mast Cell Disorders; Genomics and Proteonomics in Clonal Mast Cell Disorders; and Pediatric Expression of Mast Cell Activation Disorders.

This issue of Heart Failure Clinics--edited by Drs. Giuseppe Limongelli, Sharlene Day, and Perry Elliott--will cover Clinical and Molecular Aspects of Cardiomyopathies: On the Road from Gene to Therapy. Topics include, but are not limited to, Epidemiology and Clinical aspects of Genetic Cardiomyopathies, Existing and New therapies, Gene editing and gene-based therapeutics, Controversies surrounding exercise in genetic cardiomyopathies, Genetic infiltrative cardiomyopathies, LV Noncompaction, Clinical presentation and natural history of hypertrophic cardiomyopathy in Rasopathies, and Moelcular basis and new treatments of cardiac diseases in Rasopathies.

This issue of Rheumatic Disease Clinics, guest edited by Dr. Sindhu Johnson, will cover Advances in Epidemiologic Methods to Study Rheumatic Diseases. This unique volume will discuss the following topics, among others: Minimal clinically important difference (MCID) for outcome measures, Alternative longitudinal study designs, Propensity score methods for observational data, Approaches to deal with missing data, Applied Bayesian Methods in Rheumatology, Qualitative methods, Similarity Network Fusion, Systematic reviews/meta-analysis and randomized trials, and Integrated analysis of data obtained in various reading campaigns of images.

This issue of Psychiatric Clinics, guest edited by Dr. Thomas Franklin, will provide a unique look into several key topics in Psychodynamic Psychiatry. Articles in this volume include, but are not limited to: Preserving the Person in contemporary psychiatry, Psychodynamic psychiatrist as advocate, The role of Personality Dynamics and Disrupted Grieving, Obstacles for Parity for Psychotherapy Benefits, Psychodynamic Theory and Treatment of PTSD, Using Transference-Focused Psychotherapy (TFP) principals in Acute Care Settings, The Overall Diagnosis, Innovative educational initiatives to train psychodynamic psychiatrists in underserved areas of the world, and Psychodynamic treatment of substance use disorders.

This issue of Endocrinology and Metabolism Clinics, edited by Dr. Ashley Grossman, will focus on Innovations in the Management of Neuroendocrine Tumors. Topics include, but are not limited to, Molecular targeted therapy of NETs - State of the art; Surgical approaches to the management of liver metastases; Liquid biopsies for NETs - circulating tumour cells and DNA; Novel functional imaging of NETs; The problem of appendiceal carcinoids; Peptide radioreceptor therapy comes of age; Current chemotherapy use in NETs; The problem of grade 3 NETs; Molecular genetic studies of pancreatic neuroendocrine tumours reveal new therapeutic approaches; The new WHO classification; Gastrinomas - medical or surgical treatment; When and how to use somatostatin analogues; The NETest as the way forward; Lung and thymic carcinoids; Carcinoid heart disease; Gastric carcinoids; New treatments for the carcinoid syndrome; and The genesis of the NETs concept - From Oberdorfer to 2018.

With consultation of Dr. Bonita Stanton, Consulting Editor, Drs. Li and Higgins have secured experts in the field to provide clinical reviews on the latest updates in diagnosing and treating children with rheumatologic disease. The issue contains articles on the following topics: Approach to the Child with Joint Pain; What goes wrong that Leads to Rheumatic Disease; Juvenile Idiopathic Arthritis; Spondyloarthropathies; Systemic Arthritis; Systemic Lupus Erythematosus; Sjogren's and Mixed CTD in Children and Adolescents; Idiopathic Inflammatory Myopathies in Children; Juvenile Scleroderma; Chronic Non-Infectious Osteomyelitis and Chronic Recurrent Multifocal Osteomyelitis; Non-Inflammatory Musculoskeletal Pain in Children or Pediatric Pain Syndromes; Complications of Immunosuppressive and Biologic Response Modifier Therapy; General Health Concerns and Fitness for the Child with Rheumatic Disease; Transition of Rheumatic Disease Care: Pediatric to Adult Care; and Advocacy for Children with Rheumatic Diseases. Readers will be able to utilize the information in the issue to improve outcomes in patients with rheumatologic disease.

With collaboration from Consulting Editor Dr. Norman Gitlin, Dr. Rosenthal has created an issue that provides current clinical information on the diagnosis and treatment of liver diseases in children. Expert authors from top institutions have contributed review articles on the following topics: Biliary atresia; Alagille Syndrome; Hepatitis B & C in Children; NAFLD/NASH; Bile acid defects; Progressive Familial Intrahepatic Cholestasis; Autoimmune hepatitis/PSC/Overlap syndrome; Portal hypertension/Cirrhosis in Children; Alpha-1-antitrypsin deficiency; Hepatic tumors; Acute Liver Failure; and Liver transplantation in Children. Readers will come away with the information they need to make clinical decisions that will improve patient outcomes.

This issue of Critical Care Clinics, guest edited by Drs. Marie Baldisseri, Mary Reed, and Randy Wax, in collaboration with Consulting Editor John Kellum, is devoted to Intensive Care Unit in Disaster. Topics in this issue include: Intensive care role in disaster management; Preparing the ICU for disaster; Augmenting capacity; Triage; Natural disasters; Biological/pandemic disasters; Chemical disasters; Radiation; Anthropogenic (terrorist/criminal act) disasters; Special populations (i.e., chronically ill, morbidly obese, pregnant); Pediatrics; Austere environments; Hospital as disaster Ground Zero; and Special considerations (i.e., mental health, ethics, public relations).

This issue of Interventional Cardiology Clinics will explore Transcatheter mitral valve repair and replacement. Curated by the series Editor-in-Chief, Dr. Matthew J. Price, this issue will cover topics and advances in the field that are relevant for practicing clinicians. This issue is one of four selected each year by Dr. Price. The volume will include articles on: Transcatheter Mitral Valve Direct Annuloplasty With the Millipede Device, Transcatheter Mitral Valve Replacement with Intrepid, Transcatheter Mitral Valve Replacement with Tendyne, Treatment of functional mitral regurgitation with transcatheter edge-to-edge repair, Transcatheter Edge-to-Edge repair for Degenerative Mitral Regurgitation, Predicting Left Ventricular Outflow Tract Obstruction Following Transcatheter Mitral Valve Replacement, Prevention and Treatment of Left Ventricular Outflow Tract Obstruction after Transcatheter Mitral Valve Replacement, and Transatrial implantation of transcatheter heart valve for mitral disease, among others.

Drs. Robert Wachter and Lee Goldman coined the term hospitalist in their New England Journal of Medicine article in 1996. Hospital Medicine is now the fastest growing medical specialty in the United States, due in part to the evolution of inpatient care. In this issue, the Guest Editor, Dr. Nancy Spector, and Consulting Editor Dr. Bonita Stanton, have assembled expert authors to examine the changing nature of inpatient care, including the major movements and trends that have influenced hospital-based practice, patient centered care, and education in this clinical learning environment. Articles are focused on the following: Quality of Care and Quality Improvement; Evidence-based Medicine; Patient Outcomes and Metrics; Inter-professional Teams; Handoffs; Patient Centeredness; Communication with Patients; Health Literacy; Bedside Rounds; Education in the Inpatient; Clinical Learning Environment and Workplace-based Assessment; Simulation in Medical Education; Feedback; Bedside Teaching and Learning; and Hospital Medicine: State of the Specialty, Looking Forward. The intended audience for this issue are frontline providers that provide care in community hospitals and faculty in academic medical centers. Pediatricians will come away with the information they need to improve patient outcomes with evidentiary support.

This issue of Immunology and Allergy Clinics of North America, Guest Edited by Dr. Lisa Kobrynski, is devoted to Primary Immune Deficiencies. Articles in this issue include: Personalized therapy: Immunoglobulin replacement for antibody deficiency; Newborn Screening for Severe Combined Immunodeficiency: Update on newborn screening and lessons learned; Update on Advances in Hematopoietic Cell Transplantation for Primary Immunodeficiency Disorders; Hereditary Autoinflammatory Disorders: Recognition and treatment of inflammatory disorders of the immune system; Use of Immunomodulatory Agents to Treat Primary Immune Deficiencies: Mechanism-based therapy; Secondary Hypogammaglobulinemia: An increasingly recognized complication of treatment with immunomodulators and post-solid organ transplantation; Use of Vaccines in Primary Immunodeficiency; Gastrointestinal Manifestations and Complications of Primary Immunodeficiency Disorders; Hyper IgE Syndromes; Early Onset Inflammatory Bowel Disease; and Genome Testing to Diagnose Primary Immunodeficiency Disorders and to Identify Targeted Therapy.

This issue of Hematology/Oncology Clinics, guest edited by Drs. Nicole R. LeBoeuf and Cecilia Larocca, with consulting editors George Canellos and Franklin Bunn, will focus on Cutaneous Malignancy. Topics include, but are not limited to, Squamous Cell Carcinoma, Basal Cell Carcinoma, Melanoma, Malignant Neuroendocrine Tumors, Mycosis Fungoides/Sezary Syndrome, CD30+ lymphoproliferative Disorders, Rare Cutaneous T Cell Lymphoma, Cutaneous Involvement of Hematologic Malignancies, Cutaneous B Cell Lymphoma, Adnexal Tumors, Extramammary Paget''s Disease, Cutaneous sarcomas, and Cutaneous metastases.

In collaboration with Consulting Editor, Dr. Helen Boucher, Dr. Vivian Chu has created an issue that provides current clinical updates on device-associated infections. Authors are represented by experts across the world, who have contributed clinical reviews on the following topics: Intravascular Catheter-Related Bloodstream Infections; Vascular Graft Infections; Cardiovascular Implantable Electronic Device-Associated Infections; Left Ventricular Device-Associated Infections; Urinary Catheter-Associated Infections; Prosthetic Joint Infections; Neurosurgical Device-Related Infections; Breast Implant Infections; Cochlear Implant Infections; Gastrointestinal Scope-Related Infections; Understanding Biofilms and Novel Approaches to the Diagnosis, Prevention, and Treatment of Medical Device-Associated infections;  and Infections of Hemodialysis Access Devices. Readers will come away with the information they need to make informed clinical decisions that improve patient outcomes.

Guest edited by Dr. Daniel Levi, this issue of Interventional Cardiology Clinics will cover several key areas of interest related to Congenital Heart Disease Intervention. This issue is one of four selected each year by our series Editor-in-Chief, Dr. Matthew Price of Scripps Translational Science Center. Articles in this issue include, but are not limited to: Current Transcatheter Approaches for the Treatment of Aortic Coarctation in Children and Adults, Biodegradable Stents for Congenital Heart Disease, State of the Art ASD Closure Devices for Congenital Heart, New PDA Closure Devices and Techniques, Lymphatic Interventions, VSD Closure Devices, Techniques and Outcomes, Pulmonary Artery and Bronchial Stenting: Available Devices, Techniques and Outcomes, and Transcatheter Valve, and Interventions for Adults with Congenital Heart Disease.

With consultation of Dr. Bonita Stanton, Dr. James Chan has assembled a comprehensive list of articles that update the topic of kidney disorders in children. He has secured expert authors from around the world to contribute clinical reviews on the following topics: Urinary tract infection; Hematuria and proteinuria; Metabolic syndrome in childhood obesity; Hypertension; Post-infectious glomerulonephritis; Nephrotic syndrome and glomerular disease; Lupus nephritis; IgA nephropathy and anaphylactoid purpura nephropathy; Tubulointerstitial nephritis; Bartter syndrome and Gitelman syndrome; Renal tubular acidosis; Fanconi syndrome; Dent disease; Hypophosphatemic rickets; Syndrome inappropriate ADH secretion (SIADH); Nephrogenic diabetes insipidus; Hemolytic uremic syndrome and other acute kidney injuries; Chronic kidney disease and dietary measures to slow progression; and Long-term outcome of renal transplantation. Readers will come away with the most current clinical information they need to inform decisions to improve outcomes in pediatric patients.

In collaboration with Consulting Editor, Dr. Helen Boucher, Dr. Jo-Ann Young has put together a state-of the-art issue of the Infectious Disease Clinics of North America devoted to Management of Infectious Diseases in Stem Cell Transplantation and Hematologic Malignancy. Clinical review articles from expert authors are specifically devoted to the following topics, addressing both the stem cell transplant recipient and the hematologic malignancy patient: Chemotherapy Regimens for Hematologic Malignancies and Issues That Affect Infection; Stem Cell Transplantation Technical Issues That Affect Infection in The Recipient; Complications of Stem Cell Transplantation That Cause Infections; Antimicrobial Prophylaxis and Preemptive Agents and Regimens for the Prevention of Infection; Workup for Fever During Neutropenia; Herpesvirus Infections; Cytomegalovirus Infections; Respiratory Virus Infections; Other DNA Virus Infections; Bacterial Infections; Fungal Infections; Parasitic Infections; Vaccination; and Immunoglobulin Replacement. Readers will come away with the latest information they need to manage infections and improve outcomes in these patients.

This issue of Physician Assistant Clinics, Guest Edited by Jane McDaniel of Yale University, is devoted to Laboratory Medicine. Articles in this issue include: Rheumatology; Sexually Transmitted Infections; Provider Performed Microscopy Procedures; New Methods in Dementia Testing; Cardiology Testing; Thyroid Testing; Renal Function Testing; Anti-Xa for Heparin Monitoring and other Coagulation Studies; ABG Interpretation; Transfusion Medicine; Diagnostics for WBC Abnormalities: Leukocytosis/Leukopenia; Anemia Diagnostics for Iron Deficiency, B12/Folate Deficiency, Thalassemias, and Anemia of Chronic Disease; Hematology Testing for Hemolytic Anemias; and Liver Function Testing.

This issue of Clinics in Geriatric Medicine, Guest Edited by William B. Ershler, MD of the Institute for Advanced Studies in Aging and Geriatric Medicine, is devoted to Anemia in the Older Adult. Articles in this important issue include: Aging and Hematopoiesis; Prevalence of Anemia in Older Populations; Functional Consequences of Anemia in Older Patients; Mechanisms of Anemia in Older Populations; Unexplained Anemia in Older Populations; Significance of Elevated RDW in Older Populations; Iron Deficiency; Vitamin B12; Myelodysplasia; Chronic Kidney Disease and Anemia in Older Populations; Inflammation, Aging and Anemia; Emergence of Sickle Cell Disease in Older Populations; Heyde''s Syndrome; and Special Considerations for Anemia in the Nursing Home.

This issue of Cardiology Clinics, guest edited by Drs. Silvi Shah and Charuhas V. Thakar, will focus on Diabetes/Kidney/Heart Disease. Topics include, but are not limited to, Cardiorenal syndrome-Pathophysiology; Cardiorenal syndrome- treatment; Hypertensive Emergencies; Contrast induced acute kidney injury; Acute Kidney Injury, Heart failure, and health outcomes; Hypertension management in CKD/ESRD/DM; Arrhythmias/ICD/LVAD, Afib, and dialysis; Apol1 and blood pressure changes/hypertension; Novel ant-diabetic therapies and CV reduction; and Hypertensive disorders of pregnancy.

This issue of Sleep Medicine Clinics, guest-edited by Drs. Rachel Markwald and Anne Germain, focuses on Sleep and Performance. This issue is one of four selected each year by series Consulting Editor, Dr. Teofilo Lee-Chiong. Articles include: Work productivity and sleep issues; Sleep apnea and performance; Sleep and athletic performance: the role of untreated sleep issues in sports; Early detection of sleep disorders in safety critical jobs; Insomnia and performance; Exercise for improving insomnia symptoms: implications on performance; Sleep and athletic performance: sleep and visuomotor performance; Brain stimulation for improving sleep and memory; Prevalence of sleep disorders in students and academic performance; PTSD/TBI, Sleep, and Military Operational Performance; New technology for measuring sleep and assessing sleep disorders: implications for public health and safety; and Use of hypnotic medications on learning and memory consolidation.