Books in the The Clinics: Internal Medicine series

In collaboration with the Consulting Editors, Ranjan K. Thakur and Andrea Natale, Drs. Luigi Di Biase, Frank Marchlinski, and Andrea Natale have assembled an issue of Cardiac Electrophysiology Clinics on Advances in Atrial Fibrillation Ablation. Topics include, but are not limited to, Recurrent atrial fibrillation with isolated PVs, Beyond PVI in non paroxysmal atrial fibrillation, Recurrent atrial fibrillation after cryo, Recurrent atrial fibrillation after RF, high-density mapping, Expectation and Results of surrogate target beyond PVI, Lessons from epicardial mapping and ablation in refractory atrial fibrillation, Evolution of radiofrequency ablation parameters, Balloon based technologies, Energy sources, Current status of esophageal protection, Fluoroless atrial fibrillation ablation, Role of MRI imaging before and after ablation, When to stop OAC after atrial fibrillation ablation, Atrial fibrillation ablation trials, Risk Factor modification before and after atrial fibrillation ablation.

Approx.240 pages

This issue of Critical Care Clinics, guest edited by Drs. Geno Merli, Bharat Awsare, and Michael Baram, focuses on Pulmonary Embolism in the ICU. This is one of four issues each year selected by the series consulting editor, Dr. John Kellum. Articles in this issue include, but are not limited to: Making the Diagnosis of Pulmonary Embolism: Stable Versus Unstable; Risk Stratification; Overview of Management of Sub-massive and Massive Pulmonary Embolism; Standard Therapy: Systemic Thrombolytics; IR Therapy: IVC Filter and Catheter-based Therapies; Surgical Therapy: Embolectomy; Supportive Therapy: Management of Acute RV Failure; Supportive Therapy: ECMO/RVAD; Special Considerations; Therapy in Sub-populations; and Post-ICU Follow-up.

In collaboration with Consulting Editor Dr. Helen Boucher, Drs. Aruna Subramanian and Dora Yuk-Wai Ho have created an extremely timely and relevant issue for infectious disease physcians, as the field of biologics is exploding. These new agents are being used in rheumatologic diseases, hematologic malignancies, solid tumors, and other conditions; there is a lack of guidance in the literature on how to address their infectious risks.  The first 9 articles explain the mechanisms of action of the biologic agents and the infectious disease risks associated with their immune system targets.  The last few articles go into more depth on the viral, fungal, and mycobacterial infections that are potentiated by biologics, and discuss recommended prophylaxis and preventative strategies, including vaccinations. Specifically, articles are devoted to the following: TNF inhibitors; Agents targeting B cells; Agents targeting T cell activation; Direct T cell inhibition and agents targeting T cell migration and chemotaxis; IL-1 and IL-6 and other interleukin and IgE inhibition; Check-point inhibitors; Tyrosine kinase inhibitors for heme malignancies; EGFR inhibitors and other Tyrosine kinase inhibitors for solid tumors; Targeting JAK-STAT signaling and complement pathway for inflammatory diseases; Viral infections Potentiated by Biologics (and Prophylaxis); Endemic Fungal Infections Potentiated by Biologics (and prophylaxis); Mycobacterial Infections Potentiated by Biologics; and Vaccinations for patients on biologics. Readers will come away with the clinical overviews of these topics to improve prevention and management of patients treated with biologics.

Together with Consulting Editor, Dr. Charles Lightdale, Dr. Doug Rex has put together an issue of Gastrointestinal Endoscopy Clinics that provides state-of-the-art clinical coverage of colorectal screening. Expert authors from all over the world have contributed clinical reviews that will be a staple for all practicing endoscopists. The articles are devoted to the following topics: What is organized screening and what is its value; Screening decisions in the opportunistic setting;  The National Colorectal Cancer Round Table: Past performance and current and future goals; Proven strategies for increasing screening adherence; Colorectal cancer in persons under age 50: Seeking causes and solutions; Risk stratification strategies: From logistic regression to artificial intelligence;  Cost-effectiveness of current screening tests; Quality in colorectal cancer screening; Screening for the serrated pathway; FIT: The world''s colorectal cancer screening test; Fecal DNA testing: What has it accomplished and where is it headed; Is bowel preparation without complete colon clearing a viable concept: Update on flexible sigmoidoscopy, CTC, and capsule colonoscopy; Evidenced based screening strategies for a positive family history; Aspirational ADR and ideal colonoscopy performance: How long can we go between colonoscopies; and How Artificial Intelligence will impact colonoscopy and colorectal cancer screening. Readers will come away with the clinical knowledge they need to improve outcomes in colon cancer screening and prevention.

This issue of Child and Adolescent Psychiatric Clinics, guest edited by Drs. Robert Wisner-Carlson, Thomas Flis, Scott Pekrul and Robert Schloesser, will cover key topics of importance surrounding Autism Spectrum Disorders Across the Lifespan. This issue is Part II of II and one of four selected each year by our series Consulting Editor, Dr. Todd Peters. Topics discussed in this issue include but are not limited to: Evaluation of Psychiatric and Behavioral Problems, ADHD, Bipolar Disorder, Psychosis and Catatonia, ETC in Autism Spectrum Disorders, and many other topics.

This issue of Medical Clinics, guest edited by Dr. Andrew Dunn, is an Update in Hospital Medicine. Articles in this issue include: Sepsis, severe sepsis, and septic shock, Pneumonia, Acute congestive heart failure, Acute exacerbation of COPD, Acute manifestations of alcohol use disorder, Opioid use disorder, Acute Venous Thromboembolism, Acute liver Injury / Decompensated cirrhosis, Hospital-acquired infections, Peri-operative management of anticoagulation, Teamwork essentials for the hospitalist, Teaching at the bedside, and more.

This issue of Interventional Cardiology Clinics, guest edited by Dr. Hitinder Gurm, will discuss Renal Disease and coronary, peripheral and structural interventions. This issue is one of four selected each year by the series Editor-in-Chief, Dr. Matthew Price. Topics discussed in this issue will include: Contrast induced nephropathy, Pathophysiology of CIN, Implications of Renal disease in patients undergoing peripheral arterial interventions, Implications of renal disease in patients undergoing Structural interventions, Different types of contrast media, Biomarkers of CIN, Pharmacological prophylaxis of CIN, A practical approach to preventing renal complications in the catheterization laboratory, and several other topics.

Infections of the liver and biliary system are not uncommon, while most of the infections are viral in nature. Globally, viral hepatitis is a major public health problem and parallels infections such as HIV and tuberculosis and is associated with significant morbidity and mortality. Rapid advances have been made with HCV therapy at a time when the community focus has shifted to global elimination. This issue highlights some of the areas of considerable advances and challenges in viral hepatitis B and C. In addition, Hepatitis E is resurfacing as an infection of significance, particularly in the Western World where there is a prevalence of chronic infections. Gastroenterologists and hepatologists often think of viral hepatitis as the sole cause of hepatic infections, but there are other infections caused to bacteria, fungi and parasites; this issue highlights these infections as well. Articles are devoted to the following topics: Global epidemiology of viral hepatitis; Update on diagnostics in viral hapatitis; Heptatitis B: Immunization and impact on natural history and cancer incidence; Heptatitis B: Current status of therapy and future therapies; Hepatitis Delta: Prevalence, natural history, and treatment options; Hepatitis C: How good is real-life data and do  generics work: Hepatitis C: Does successful treatment alter the natural history and quality of life; Hepatitis E: Epidemiology,clinical course, prevention, and treatment; CMV and EBV infections of the liver; Extrahepatic manifestations of viral hepatitis; Pyogenic and amebic infections of the liver; and Fungal and parasitic infections of the liver.

This issue of Primary Care: Clinics in Office Practice, guest edited by Dr. Benjamin Silverberg, is devoted to Adolescent Medicine. Articles in this issue include: Disorders of Puberty; Adolescent Vaccines; School-based Health Care; Musculoskeletal Issues in Adolescents; Gender Non-conforming Health Care in Adolescents; Refugee and Immigrant Health Care in Adolescents; Human Trafficking in Adolescents; Crisis Counseling for Adolescents; Sexual Assault in Adolescents; HIV (PrEP, PEP, chronic care) in Adolescents; Sexually Transmitted Infections in Adolescents; Substance Misuse and Addiction in Adolescents; and Headaches in Adolescents.

This issue of Clinics in Laboratory Medicine will cover Precision Medicine in Practice: Molecular Diagnosis Enabling Precision Therapies. Curated by Dr. Ryan J. Schmidt, this issue is one of four selected each year by the series Consulting Editor, Milenko Tanasijevic. The volume will include articles on: Features of a Comprehensive Precision Medicine Program for Constitutional Genetic Disorders, Establishing a Precision Medicine Center of Excellence for Rare Disease, High-throughput DNA Sequencing for Rare Disease Diagnosis, Enhancing Diagnosis through RNA Sequencing, Interpretation of Rare Genetic Variants, Clinical Bioinformatics, Precision Therapies for Retinal Dystrophy, Precision Therapies for Muscular Dystrophy, Therapeutic Gene Editing, High Throughput Functional Studies of Genetic Variants, and Patient-specific Disease Models.

This issue of Clinics in Chest Medicine, guest-edited by Dr. M. Patricia Rivera, is the second of two issues focused on Lung Cancer. Topics discussed in this issue include but are not limited to: Lung Cancer TNM Staging: The 8th Edition; New Surgical Approaches in the Treatment of NSCLC; Alternatives to Surgery for Early Stage Non-Small Cell Lung Cancer: Stereotactic Radiotherapy; Alternatives to Surgery for Early Stage Non-Small Cell Lung Cancer: Thermal Ablation; Advances in the Treatment of Stage III NSCLC; Advances in Treatment of NSCLC: Targeted Therapy; Advances in the Treatment of NSCLC: Immunotherapy; Treatment of Oligometastatic Disease in NSCLC; Management of Malignant Pleural Effusions; Advances in the Treatment of Small Cell Lung Cancer; Palliative Care and the Role of the Primary Care Physician in Lung Cancer Care; Pulmonary Complications of Immunotherapy; and Pulmonary Complications of Chemotherapy and Radiation Therapy.

This issue of Clinics in Chest Medicine, guest-edited by Dr. Gerard Criner and Dr. Bartolome Celli, is focused on Chronic Obstructive Pulmonary Disease. Topics discussed in this issue include but are not limited to: COPD Pathogenesis; Epidemiology of COPD; Host, Gender, and Early Life Factors as Risks for COPD; Alpha One Antitrypsin Deficiency; Lung Function Testing; Assessing Symptom Burden; Chest Imaging in the Diagnosis and Assessment of the Patient with COPD; Biomarkers in the Diagnosis and Assessment of COPD; Asthma/COPD Overlap; Multimorbidity in the Patient with COPD; Definition Causes, Pathogenesis, and Consequences of Exacerbations; Treatment of Acute Exacerbations; Prevention of Exacerbations; Bronchodilators; Benefits and Risks of Inhaled Corticosteroids in COPD; Systemic Medications; Smoking Cessation/Vaccinations; Pulmonary Rehabilitation; Oxygen Therapy/Noninvasive Ventilation; and Interventional and Surgical Therapies for COPD.

Together with Consulting Editor Dr. Bonita Stanton, Guest Editors Dr. Max Coppes and Leontein Kremer have put together a comprehensive monograph that updates pediatricians on pediatric cancer survivorship. They have selected worldwide experts who have contributed the most current clinical reviews to provide the information you need for care of the pediatric cancer patient. Articles are devoted specifically to the following topics: Stories from survivors and introduction to survivorship; What we know about survivors and how we know this: Early studies, early cohorts, registries and current cohorts of survivors; Radiotherapy and late effects; Guidelines for survivorship care after childhood cancer; Lifestyle, fatigue, social integration in survivors; Psychological & neurocognitive health; Second cancer risk: Risk, exposures, genetics;  Cardiovascular (including genetics ) and pulmonary disease; Fertility and reproductive complications; Endocrine health conditions, including thyroid, growth, bone, and metabolic syndrome; Renal and hepatic health after childhood cancer; Hearing and other neurologic problems; and The future of survivorship (future challenges and research) including new agents. Pediatricians will come away with the information they need to improve patient outcomes.

In collaboration with Consulting Editor, Dr. Norman Gitlin, Guest Editor Dr. Catherine Frenette has assembled expert authors to provide current updates on Hepatocellular Carcinoma (HCC). This issue asks important questions and provides answers and current thoughts on the staging and treatment of HCC.  Clinical review articles are specifically dedicated to the following topics: The Changing Global Epidemiology of Hepatocellular Carcinoma; Prevention Strategies for HCC; Biomarkers or Biopsy for Diagnosis of HCC; Screening and Surveillance Strategies to Improve the Chance of Success; Imaging Diagnosis of HCC; Surgical Resection: Old dog--Any new tricks; Hepatocellular Carcinoma and Liver Transplant: How Will Organ Allocation Changes Affect the HCC Patient Within Transplant Criteria; Downstaging to Liver Transplant: Success Involves Choosing the Right Patient; Locoregional Therapies for Hepatocellular Carcinoma: What has Changed in the Past Ten Years; External Beam Radiotherapy: Is There a Place for This in HCC Treatment; Tyrosine Kinase Inhibitors and Hepatocellular Carcinoma; Immuno-oncology for Hepatocellular Carcinoma: The Present and the Future; Management of Side Effects of Systemic Therapies for HCC: Guide for the Hepatologist; and Why a Multi-disciplinary Tumor Board is Critical for Success with Hepatocellular Carcinoma. Readers will come away with the information they need to improve patient outcomes in the patient with HCC.

This issue of Clinics in Chest Medicine, guest-edited by Drs. Carrie A. Redlich, Kristin J. Cummings, and Peggy Lai, is focused on Advances in Occupational and Environmental Lung Diseases. Topics discussed in this issue include but are not limited to: Master Clinician - selected occupational and environmental pulmonary cases; Chest imaging in the Diagnosis of Occupational Lung Diseases; Harnessing electronic medical records to enhance the diagnosis of work-related lung diseases; The impact of health disparities on lung disease; Respiratory health effects of exposure to cleaning products; Occupational upper airways disorders, including laryngeal dysfunction; Occupational bronchiolitis - including flavoring-related lung disease, deployment; Coal workers pneumoconiosis and other mining-related lung disease: the re-emergence of an old disease (including COPD in miners); Occupational contributions to ILD (including asbestos, overlap HP and ILD); Silicosis - Persistence of an old disease, old and new exposure settings and prevention; Occupational respiratory cancer: Chest CT screening; Occupational respiratory Infections: pneumonia, healthcare workers; Update on climate change: its impact on respiratory health at work, home, and at play; The changing nature of wildfires: update on the respiratory health of first responders and communities; The microbiome and damp Indoor environments; The on-going impact of World Trade Center exposures on respiratory health; The impact of Electronic cigarettes and smoking cessation; The respiratory risks of ambient /outdoor air pollution; and Indoor air pollution and respiratory health.

This issue of Sleep Medicine Clinics has been compiled by esteemed Consulting Editor, Teofilo Lee-Chiong, and brings together recent sleep medicine articles that will be useful for Primary Care Providers. Topics include: Internet-Delivered Cognitive Behavioral Therapy for Insomnia Tailoring Cognitive Behavioral Therapy for Insomnia for Patients with Chronic Insomnia; Prescription Drugs Used in Insomnia; Hypnotic Discontinuation in Chronic Insomnia; Evaluation of the Sleepy Patient Differential Diagnosis; Subjective and Objective Assessment of Hypersomnolence; Pharmacologic Management of Excessive Daytime Sleepiness; Nonpharmacologic Management of Excessive Daytime Sleepiness; Treatment of Obstructive Sleep Apnea Choosing the Best Positive Airway Pressure Device; Treatment of Obstructive Sleep Apnea Choosing the Best Interface; Treatment of Obstructive Sleep Apnea Achieving Adherence to Positive Airway Pressure Treatment and Dealing with Complications; Oral Appliances in the Management of Obstructive Sleep Apnea; Avoiding and Managing Oral Appliance Therapy Side Effects; Positional Therapy for Positional Obstructive Sleep Apnea; Pharmacologic and Nonpharmacologic Treatment of Restless Legs Syndrome; Drugs Used in Parasomnia; Drugs Used in Circadian Sleep-Wake Rhythm Disturbances; Sleep in the Aging Population; and Sleep, Health, and Society.

This issue of Cardiac Electrophysiology Clinics, Guest Edited by Drs. Jason Bradfield and Kalyanam Shivkumar, is dedicated to Epicardial Interventions in Electrophysiology. This is one of four issues selected each year by the series Consulting Editors, Ranjan K. Thakur and Andrea Natale. Topics include, but are not limited to, Anatomy of the Pericardial Space, Techniques for Percutaneous Access, Peri-operative Imaging to Guide Epicardial Mapping and Ablation, Epicardial Ablation of Idiopathic Ventricular Tachycardia, Epicardial Ablation of Ischemic Ventricular Tachycardia, Epicardial Ablation of Non-ischemic Ventricular Tachycardia, Epicardial Ablation of Arrhythmogenic Right Ventricular Cardiomyopathy, Epicardial Ablation of Ventricular Arrhythmia secondary to Brugada Syndrome, Epicardial Ablation of Supraventricular Tachycardia, Epicardial Ablation of Atrial Fibrillation, Hybrid Surgical Epicardial Ablation, Epicardial Ablation via the Arterial and Venous System, Epicardial Ablation Biophysics and novel Radiofrequency Energy Delivery Techniques, Epicardial Ablation Complications, and The Future of Epicardial Interventions.

This issue of Clinics in Laboratory Medicine, guest edited by Drs. Nicole D. Pecora and Matthew Pettengill, will cover Current Issues in Clinical Microbiology. This issue is one of four selected each year by our Editor-in-Chief, Dr. Milenko Jovan Tanasijevic. Topics discussed in this issue will include: Update in Diagnostics of Bloodstream Infections, Panels and Syndromic Testing in Clinical Microbiology, Lab Consolidation and Centralization, Update in Susceptibility Testing: Phenotypic and Genotypic Methods, Genomics in the Clinical Microbiology Laboratory, Automation in the Clinical Microbiology Laboratory, Coronavirus Detection in the Clinical Microbiology Laboratory: Are We Ready for Identifying and Diagnosing a Novel Strain?, Update on Biosafety and Emerging Infections for the Clinical Microbiology Lab, Update in Clinical Mycology, Point of Care Testing in Microbiology, Pediatric Diagnostic Microbiology, Antimicrobial Stewardship: What the Clinical Laboratory Needs to Know, Fellowship Training for the Future Clinical Microbiology Laboratory Director, Update in Diagnostics/Susceptibility of Mycobacterial Diseases, Role of the Clinical Microbiology Lab in One Health, Update in Infectious Disease Diagnosis in Surgical Pathology, and more.

This issue of Heart Failure Clinics, guest edited by Drs. Clyde W. Yancy and R. Kannan Mutharasan, will cover Process Improvement in Heart Failure. This issue is one of four issues selected each year by our series consulting editor, Dr. Eduardo Bossone. Topics discussed in this issue will include: Approaching Process Improvement, Identifying Heart Failure Patients, Predicting High-risk Patients and High-Risk Outcomes in Heart Failure, Selecting the Correct Target for Improvement in Heart Failure Care and Improving Adherence, Empowering Patients Living with Heart Failure with Social Media and Technology, Transitioning Heart Failure Patients to Outpatient Care, Innovating Outpatient Processes of Care and Anticipating Complex Care Algorithms, Addressing Co-morbidities in Heart Failure, Systematizing Heart Failure Population Health, Defragmenting Heart Failure Care, and Adapting to the Payment Landscape.

This issue of Endocrinology and Metabolism Clinics will cover Pediatric Endocrinology. Curated by Dr. Andrea Kelly, this issue will explore topics in the field that are relevant for practicing clinicians. This issue is one of four selected each year by the series Consulting Editor, Adriana G. Ioachimescu. The volume will include articles on: Endocrine Sequelae in Childhood Cancer Survivors, Bone Health in Childhood Chronic Disease, Advances in Bone Health Assessment, Inhaled Glucocorticoids and Endocrine Outcomes, Atypical DM (mitochondrial, transplant, CFRD, monogenic), Pediatric Thyroid Cancer (outcomes, genetics, therapeutics), New Technologies in Type 1 diabetes (bionic pancreas, insulin, mobile health), Precocious and Delayed Puberty-Genetic Underpinnings and treatments (various GNRH formulations, implant), Pediatric Type 2 diabetes, Adolescent health outcomes in relation to phthalates.

This issue of Primary Care: Clinics in Office Practice, guest edited by Dr. Parvathi Perumareddi, is devoted to Nephrology. Articles in this issue include: Electrolyte Abnormalities, Pre-renal Azotemia, and Fluid Balance, Acute Kidney Injury, Chronic Kidney Disease and Chronic Renal Failure, Nephrotic Syndrome, Nephritic Syndrome (not urological), Renovascular Hypertension, Diabetic Nephropathy, Nephrolithiasis, Polycystic Kidney Disease, Renal Repercussions of Medications, Care of the Renal Transplant Patient, and more.

This issue of Anesthesiology Clinics, guest edited by Drs. Alison Perate and Vanessa Olbrecht, focuses on Pediatric Anesthesia. This is one of four issues each year selected by the series consulting editor, Dr. Lee Fleisher. Articles in this issue include, but are not limited to: The Pediatric Difficult Airway: Updates and Innovations; Current Knowledge of the Impact of Anesthetics on the Developing Brain; Anesthesia for Innovative Pediatric Surgical Procedures; Pediatric Mass Casualty Preparedness; The Pediatric Burn: Current Trends and Future Directions; Managing the Child with Complex Congenital Heart Disease; Modernizing Education of the Pediatric Anesthesiologist; Regional Anesthesia: Options for the Pediatric Patient; Managing the Pediatric Patient for Anesthesia Outside of the OR; New Trends in Fetal Anesthesia; Anesthetic Implications of the Common Congenital Anomalies; Managing the Adult Patient with Congenital Disease; Trends in Pain Management: Thinking Beyond Opioids; Sustainability in the OR: Reducing Our Impact on the Planet; Current Trends in OSA; and Processed EEG Guided Propofol Infusion in Children.

This issue of Clinics in Laboratory Medicine, guest edited by Dr. A. Zara Herskovits, will cover Laboratory Testing for Neurologic Disorders. This issue is one of four selected each year by our Editor-in-Chief, Dr. Milenko Jovan Tanasijevic. Topics discussed in this issue will include: molecular approach to diagnostic testing for children with developmental delay and congenital anomalies, proteopathic and seeding assays (such as RT-QUIC), genetic testing for ALS and FTD, Diagnostic and prognostic testing for Alzheimer''s disease, confounds in the interpretation of paraneoplastic antibody panels, Review of neurologic disease sendout testing at an academic medical center, development of new diagnostic tests for neurologic disorders, assuring quality in laboratory testing for sendout reference tests, diagnostic testing for patients with spinal muscular atrophy, among others.

In collaboration with Consulting Editor, Dr. William Rayburn, Guest Editor Dr. Edward Chien has created a state-of-the-art monograph that focuses on Premature Rupture of Membranes. The issue separates articles into three sections: Prediction and Prevention, Interventions, and Special Topics, with articles on the following topics: Vaginal Microbiome; Cervical and Fetal Membrane Biomechanics; Management of the Short Cervix, Prolapsing Membranes, and Rescue Cerclage; Time to Deliver: Early - Late Preterm Management; Tocolysis; Use of Corticosteroids in Premature Rupture of Membranes; Antibiotics Prophylaxis for PPROM; Viral Infections (HIV, Hep B, Herpes, HCV); Antenatal Monitoring after PPROM; Periviable PROM; PPROM in Multiple Gestations and after Fetal Surgery; and Neonatal Issues after PPROM. Readers will come away with the current and clinical information they need to improve patient outcomes.

This issue of Interventional Cardiology Clinics, guest edited by Editor-in-Chief Matthew J. Price, will focus on Key Trials of the Decade. Trials discussed in this issue will include: Physiology over Angiography to determine lesion severity: The FAME trials; Percutaneous Coronary Intervention or surgery for multivessel disease: The SYNTAX trial at 10 years; Percutaneous Coronary Intervention or surgery for unprotected left main disease: The EXCEL trial at 5 years; Complete or Incomplete Revascularization for ST-Elevation Myocardial Infarction: the PRAMI trial and beyond; Abbreviated Dual Antiplatelet Therapy after PCI in High Bleeding Risk Patients: LEADERS-FREE and ONYX ONE; Transcatheter treatment of functional mitral regurgitation in patients with heart failure: The COAPT trial; Manual thrombectomy in Primary Percutaneous Coronary Intervention: Lessons learned from TOTAL; Paradigm shifts in the treatment of aortic stenosis: The PARTNER Trials experience; COURAGE and ORBITA in context: PCI for chronic stable CAD; SIMPLICITY to RADIANCE: Interpreting the past and mapping the future of renal denervation; From WOEST to AUGUSTUS: Dual Therapy after PCI; The ISCHEMIA Trial: Background, Design, Outcomes and Clinical Interpretation.

This issue of Immunology and Allergy Clinics, guest edited by Dr. Lanny Rosenwasser, will provide up-to-date clinical concepts regarding Biologics for the Treatments of Allergic Conditions. Articles in this outstanding issue include: Allergic Rhinitis/CRS/Polyposis, Eosinophilic Asthma, Pediatric Asthma, Severe Asthma, ACOS/COPD, Food Allergy, Atopic Dermatitis, Chronic Urticaria, Anaphylaxis, Drug Allergy, Cell Disorders, Biologics and Immunotherapy, and much more.

This issue of Hematology/Oncology Clinics, Guest Edited by Dr. Raymond L. Comenzo, is devoted to Systemic Amyloidosis due to Monoclonal Immunoglobulins. This issue is one of six selected each year by our series Consulting Editors, George P. Canellos and Edward J. Benz. Topics discussed in this important issue include: The Spectrum of Monoclonal Immunoglobulin Diseases, Systemic Amyloidosis due to Clonal Plasma Cell Diseases, Systemic Amyloidosis due to Low-grade Lymphomas, The Process of Amyloid Formation due to Monoclonal Immunoglobulins, Cardiac Involvement, Renal Involvement, Liver and Gastrointestinal Involvement, Peripheral Nervous System Involvement, Options for Chemotherapy, Stem-cell Mobilization and Autologous Transplant, Monoclonal Antibody Therapies, Solid Organ Transplant, Supportive Care, Patient Voices, and Future Perspectives.