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PARP Inhibitors for Cancer Therapy provides a comprehensive overview of the role of PARP in cancer therapy. PARP plays a pivotal role in DNA repair and may contribute to the therapeutic resistance to DNA damaging agents used to treat cancer.
This book represents the first systematic attempt to analyse media and public communications published in Britain by people of African and Afro-Caribbean origin during the aftermaths of war, presenting an in-depth study of print publications for the period 1919-1924.
This volume, which is dedicated to Heinz Langer, includes biographical material and carefully selected papers. Heinz Langer has made fundamental contributions to operator theory.
This collection documents the work of the Hyperuniverse Project which is a new approach to set-theoretic truth based on justifiable principles and which leads to the resolution of many questions independent from ZFC.
The Proceedings volume contains 16 contributions to the IMPA conference "New Trends in Parameter Identification for Mathematical Models", Rio de Janeiro, Oct 30 - Nov 3, 2017, integrating the "Chemnitz Symposium on Inverse Problems on Tour". This conference is part of the "Thematic Program on Parameter Identification in Mathematical Models" organized at IMPA in October and November 2017. One goal is to foster the scientific collaboration between mathematicians and engineers from the Brazialian, European and Asian communities. Main topics are iterative and variational regularization methods in Hilbert and Banach spaces for the stable approximate solution of ill-posed inverse problems, novel methods for parameter identification in partial differential equations, problems of tomography , solution of coupled conduction-radiation problems at high temperatures, and the statistical solution of inverse problems with applications in physics.
This book focuses on developments in complex dynamical systems and geometric function theory over the past decade, showing strong links with other areas of mathematics and the natural sciences.Traditional methods and approaches surface in physics and in the life and engineering sciences with increasing frequency - the Schramm-Loewner evolution, Laplacian growth, and quadratic differentials are just a few typical examples. This book provides a representative overview of these processes and collects open problems in the various areas, while at the same time showing where and how each particular topic evolves. This volume is dedicated to the memory of Alexander Vasiliev.
This highly readable book aims to ease the many challenges of starting undergraduate research. It accomplishes this by presenting a diverse series of self-contained, accessible articles which include specific open problems and prepare the reader to tackle them with ample background material and references. Each article also contains a carefully selected bibliography for further reading.The content spans the breadth of mathematics, including many topics that are not normally addressed by the undergraduate curriculum (such as matroid theory, mathematical biology, and operations research), yet have few enough prerequisites that the interested student can start exploring them under the guidance of a faculty member. Whether trying to start an undergraduate thesis, embarking on a summer REU, or preparing for graduate school, this book is appropriate for a variety of students and the faculty who guide them.
This book contains selected papers based on talks given at the "Representation Theory, Number Theory, and Invariant Theory" conference held at Yale University from June 1 to June 5, 2015.
This book investigates the convergence and summability of both one-dimensional and multi-dimensional Fourier transforms, as well as the theory of Hardy spaces.
This book discusses normal sex-related differences in lung structure and function and the role these differences play in lung disease.
The second edition of this book updates and expands upon a historically important collection of mathematical problems first published in the United States by Birkhäuser in 1981. These problems serve as a record of the informal discussions held by a group of mathematicians at the Scottish Café in Lwów, Poland, between the two world wars. Many of them were leaders in the development of such areas as functional and real analysis, group theory, measure and set theory, probability, and topology. Finding solutions to the problems they proposed has been ongoing since World War II, with prizes offered in many cases to those who are successful.In the 35 years since the first edition published, several more problems have been fully or partially solved, but even today many still remain unsolved and several prizes remain unclaimed. In view of this, the editor has gathered new and updated commentaries on the original 193 problems. Some problems are solved for the first time in this edition. Included again in full are transcripts of lectures given by Stanislaw Ulam, Mark Kac, Antoni Zygmund, Paul Erdös, and Andrzej Granas that provide amazing insights into the mathematical environment of Lwów before World War II and the development of The Scottish Book. Also new in this edition are a brief history of the University of Wroclaw's New Scottish Book, created to revive the tradition of the original, and some selected problems from it.The Scottish Book offers a unique opportunity to communicate with the people and ideas of a time and place that had an enormous influence on the development of mathematics and try their hand on the unsolved problems. Anyone in the general mathematical community with an interest in the history of modern mathematics will find this to be an insightful and fascinating read.
This new edition is devoted to a broad array of topics involving the circadian variation in cardiovascular diseases, with focuses on hypertension, stroke, and coronary disease. The volume covers clinical and device research related to home and ambulatory BP monitoring, as there have been significant advances in technology since the publication of the previous edition. In addition, there is an increased focus on the applicability of home and ambulatory BP monitoring in drug development in all therapeutic arenas. The text features contributions from chapter authors from around the world and who have great expertise in cardiovascular medicine, therapeutics, clinical trials, and evidence-based medicine.Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics, Third Edition is essential reading for a large audience, including those practicing cardiology and nephrology with a special focus in hypertension, geriatrics and internal medicine, clinical trialists, regulators in the US, Europe, and Japan, and physicians in training in cardiology, hypertension, pharmacology, nephrology and neurology.
This book features a series of lectures that explores three different fields in which functor homology (short for homological algebra in functor categories) has recently played a significant role.
This proceedings volume originates from a conference held in Herrnhut in June 2013. It provides unique insights into the power of abstract methods and techniques in dealing successfully with numerous applications stemming from classical analysis and mathematical physics. The book features diverse topics in the area of operator semigroups, including partial differential equations, martingale and Hilbert transforms, Banach and von Neumann algebras, Schrödinger operators, maximal regularity and Fourier multipliers, interpolation, operator-theoretical problems (concerning generation, perturbation and dilation, for example), and various qualitative and quantitative Tauberian theorems with a focus on transfinite induction and magics of Cantor.The last fifteen years have seen the dawn of a new era for semigroup theory with the emphasis on applications of abstract results, often unexpected and far removed from traditional ones. The aim of the conference was to bring together prominent experts in the field of modern semigroup theory, harmonic analysis, complex analysis and mathematical physics, and to present the lively interactions between all of those areas and beyond. In addition, the meeting honored the sixtieth anniversary of Prof C. J. K. Batty, whose scientific achievements are an impressive illustration of the conference goal. These proceedings present contributions by prominent scientists at this international conference, which became a landmark event.They will be a valuable and inspiring source of information for graduate students and established researchers.
This volume reflects "New Trends in Shape Optimization" and is based on a workshop of the same name organized at the Friedrich-Alexander University Erlangen-Nurnberg in September 2013. some focus on the topics discussed at the Workshop, while others involve arguments outside its scope but which are no less relevant for the field today.
This contributed volume contains articles written by the plenary and invited speakers from the second international MATHEON Workshop 2015 that focus on applications of compressed sensing.
This monograph discusses covariant Schroedinger operators and their heat semigroups on noncompact Riemannian manifolds and aims to fill a gap in the literature, given the fact that the existing literature on Schroedinger operators has mainly focused on scalar Schroedinger operators on Euclidean spaces so far.
This textbook acts as a pathway to higher mathematics by seeking and illuminating the connections between graph theory and diverse fields of mathematics, such as calculus on manifolds, group theory, algebraic curves, Fourier analysis, cryptography and other areas of combinatorics.
This case-based text provides treatment approaches to common and uncommon movement disorders. Other disorders covered are drug-induced movement disorders, psychogenic movement disorders, Wilson's disease, hemifacial spasm and more.
This volume consists of contributions spanning a wide spectrum of harmonic analysis and its applications written by speakers at the February Fourier Talks from 2002 - 2016.
Brauer had already introduced the defect of a block and opened the way towards a classification by solving all the problems in defects zero and one, and by providing some evidence for the finiteness of the set of blocks with a given defect.
This new book examines the relationship between agency theory and executive pay. An insightful and revolutionary read for those researching corporate governance, HRM and organisation theory, this useful book offers potential solutions to some of the problems with executive pay and the standard model of agency.
This open access book presents five different approaches to reading breath in literature, in response to texts from a range of historical, geographical and cultural environments.
Arab Film and Video Manifestos presents, in their entirety, five key documents that have fundamentally shaken up and helped change the face of image culture in the Middle East and beyond.
The conclusion asserts that The Walking Dead presents both queer alternatives to and damaging contradictions within the traditional heterosexual family model, helping to question this model and to consider the struggle of queer American families.
Perspectives on Everyday Life: A Cross Disciplinary Cultural Analysis makes the argument for studying everyday life through a combination of introductory theoretical approaches and a grouping of applications to specific aspects of American culture.
This volume presents a distinctively Lacanian psychoanalytic approach to the theorizing, understanding, and critique of curriculum in higher education. In this work, the author presents the main theories of curriculum in the current discourse, develops a notion of critique, and applies it to existing global guidelines for curriculum reform.
This book discusses what it means for cities to work toward and achieve resilience in the face of climate change. The chapters for each case delve into the current status of the cities and issues resilience must overcome, and then explore solutions and key takeaways learned from the implementation of various resilience approaches.
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