Books published by Caister Academic Press

The most important recent advances. Topics include: toxins on mobile genetic elements, botulinum neurotoxins, anthrax, subtilase cytotoxin, Pasteurella multocida toxin, RTX toxins of vibrios, vacA toxin, staphylococcal immune evasion toxins and fungal ribotoxins.

Experienced and authoritative experts review the most important innovations and their biotechnological applications. An interdisciplinary view that examines the area from molecular biology, genome-, transcriptome- and proteome-wide perspectives, and looks at the ecological aspects and systems biology approaches.

The focus is on the topical and most relevant aspects and the authors give readers an insight into the current understanding of the subject and the future direction of research.

Includes phylogenetics, taxonomy, comparative genomics, functional genomics, intestinal microflora, surface proteins, stress responses, immune system, probiotics, anti-cancer potential, and much more.

Extensive publication on bacterial secreted proteins, secretory systems and their vital role in bacterial pathogenesis. Immense value to all microbiologists, molecular biologists, public health scientists and other researchers and professionals.

The most important developments in the field. An invaluable, up-to-date summary of the molecular biology and genomics of plant pathogenic bacteria. A timely review of the current and most topical areas of research.

Essential manual providing a comprehensive guide to the most up-to-date technologies and applications as well as providing an overview of the theory of this increasingly important technique.

Written by expert, internationally renowned scientists, this comprehensive volume describes in detail the use of microorganisms for the production of the most important biopolymers and polymer precursors.

First coherent picture of Leishmania molecular and cellular biology since the publication of the genome sequence. A molecular and genomic perspective of Leishmania-specific aspects of trypanosomatid biology and pathology.

The molecular mechanisms and biological processes in which epigenetic modifications play a primordial role are described in detail.

Focuses on molecular biology and genomics. Include metal biology, redox chemistry, respiration, sugar catabolism, nucleic acid modification, DNA replication, repair and recombination, signal transduction and transcriptomics.

Describes and explains some of the more complex aspects of real-time PCR presenting a background for the novice, a theoretical reference for the experienced user, and useful discussions of future developments.

The expertise and enthusiasm of an international panel of leading cyanobacterial researchers provides a state-of-the art overview of the field.

A collection of reviews by the world's leading experts in AIDS vaccine research.

This unique polymerase chain reaction (PCR) troubleshooting guide is an essential companion for readers with some experience in PCR. The book discusses the many and varied problems encountered with PCR, together with tips, advice, and procedures to obviate rather than overcome the PCR problems. The advice in PCR Troubleshooting is invaluable.

Microbes have evolved in an impressive and diverse range of strategies to subvert the host immune system. Two major types of strategies exist. The first is the evasion of recognition by the host, for example by using antigenic variation, masking of epitopes, the use of decoys, molecular mimicry, etc. The second is the modulation and/or suppression of the innate (e.g. complement, NK cells) and adaptive (e.g. antibodies) immune responses. A better understanding of the underlying mechanisms involved is critical for the rational design of novel therapeutic agents and vaccines to treat and/or prevent infectious diseases. Another area of active research is the application of microbial immunomodulatory factors in the treatment of human immunological disorders (e.g. inflammatory bowel disease and asthma) and as sources of pharmacologically active agents. In this book, internationally renown scientists critically review the current cutting-edge research in this area. Topics covered include the

World renowned scientists critically review the most important issues in this rapidly expanding field.

Reviews current aspects of research providing a fascinating insight into papillomavirus molecular biology, interactions with the host, immunology and vaccine development.