Books published by Elsevier Science Publishing Co Inc

International Review of Neurobiology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Crystallography of Protein Dynamics, Volume 687, the latest release in this important series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

Vitamins and Hormones serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Wetzel's Limnology: Lake and River Ecosystems, Fourth Edition, presents a fully updated revision of the classic Limnology: Lake and River Ecosystems - published in 2001. The coverage remains rigorous and uncompromising and has been thoroughly reviewed and updated with evolving recent research results and theoretical understanding. This new edition brings a new format to this well-established work as we see each chapter fully updated by an individual contributor, or contributor team. Each contributor is an expert in the field and brings a comprehensive and global perspective. The editors provide a clear voice throughout, ensuring the chapters have strong continuity. This is an essential text for an undergraduate on any limnology course.

100 thoroughly revised coronal diagrams and accompanying photographic plates spaced at approximately 120 µm intervals 32 thoroughly revised sagittal diagrams and accompanying photographic plates 30 thoroughly revised horizontal diagrams and accompanying photographic plates Photographic plates printed from high resolution digital images in color The most accurate and virtually universally used stereotaxic coordinate system Over 800 structures identified Includes the Expert Consult eBook version, compatible with PC, Mac, and most mobile devices and eReaders, which allows readers to browse, search, and interact with content

Pharmacogenomics: From Discovery to Clinical Implementation is a complete reference aimed at building a solid foundation of the key concepts in this fast-moving knowledge area. The book's chapters over the foundational aspects of pharmacogenomics, including drug metabolism, drug discovery, development, and testing, and then detail studies of key health conditions and the potential therapeutic applications of pharmacogenomics. Diseases covered include diabetes, cardiovascular diseases, psychiatric disease, cancer, pulmonary and respiratory diseases, viral diseases, gastroenterology, autoimmune diseases, immunosuppressants, and, finally, an overview of computational resources. This is the perfect resource for pharmaceutical science graduate students to learn the key concepts of the area. However, researchers and graduate students in the related fields of genetics, pharmacoepidemiology, molecular biology, and medicinal chemistry will also benefit from the structured approach of the book.

Advances in Child Development and Behavior, Volume 65, the latest release in this classic resource on the field of developmental psychology, includes a variety of timely updates, with this new volume presenting interesting chapters written by an international board of authors.

Discrete Mathematics provides key concepts and a solid, rigorous foundation in mathematical reasoning. Appropriate for undergraduate as well as a starting point for more advanced class, the resource offers a logical progression through key topics without assuming any background in algebra or computational skills and without duplicating what they will learn in higher level courses. The book is designed as an accessible introduction for students in mathematics or computer science as it explores questions that test the understanding of proof strategies, such as mathematical induction. For students interested to dive into this subject, the text offers a rigorous introduction to mathematical thought through useful examples and exercises.

Agrios' Plant Pathology, Sixth Edition is the ultimate reference in the field. Here, Dr. Richard Oliver provides a fully updated table of contents with revised and new chapters and invited contributors from around the globe. Building on the his legacy, this new edition is an essential read for students, faculty and researchers interested in plant pathology. Sections outline how to recognize, treat and prevent plant diseases and provide extensive coverage on abiotic, fungal, viral, bacterial, nematode and other plant diseases and their associated epidemiology. A large range of case studies take a deep dive into the genetics and modern management of several plant species.

Advances in Microbial Physiology, Volume 83 in this ongoing serial, highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Topics of interest in this update include RidA paradigm, Targeting the cell envelope to overcome antimicrobial resistance, Biosynthesis and function of microbial methylmenaquinones, Antibiotic efficacy, Role of central metabolism/bacterial physiology on tolerance to cell wall-acting antibiotics, and Physiology of diazotrophs.

Advances in Immunology, Volume 158, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology.

Viral Vectors in Cancer Immunotherapy, Volume 379 in the International Review of Cell and Molecular Biology presents the latest on cancer immunotherapy and how it has transformed cancer treatment through advances in immune checkpoint inhibitors and adoptive cell therapy.  Chapters in this new release include Past, present and future of viral vectors in cancer immunotherapy, Alphaviruses in cancer immunotherapy, Adenoviral-based cancer gene therapy, Armored modified vaccinia Ankara in cancer immunotherapy, Strategies of Semliki Forest virus in immuno-oncology, Maraba virus in cancer immunotherapy, Oncolytic viruses in hematological malignancies, Oncolytic virus for cancer therapies: Overview and future directions, and more. The use of genetically modified viruses allows the expression of pro-inflammatory molecules, while the immune system receives danger signals from the viruses themselves. In some cases, the virus can also induce tumor cell death. This book will review advances in virus-based cancer immunotherapy in both solid tumors and hematologic malignancies.

Pulmonary Pharmacology, Volume 98 provides in-depth reviews on the latest progresses about respiratory medicine research. Topics covered in this volume include an Update on Asthma Pathogenesis and New Therapeutic Targets, Progress in the Novel Therapeutic Targets for the Treatment of COPD, Update on Pulmonary Fibrosis Pathogenesis, Bronchodilators in Lung Diseases: from Potential Therapeutic Approaches to Current Challenges, Mechanisms of Action of Corticosteroids in Lung Diseases, Monoclonal Antibodies for the Treatment of Asthma: An Update, Asthma and COPD Exacerbation and Therapeutic Strategies, and more. Other chapters cover Phosphodiesterase Inhibitors and Lung Diseases, Specialized Pro-Resolving Mediators in Lung Diseases, Anti-Fibrotic Strategies and Pulmonary Fibrosis, Renin Angiotensin System and Lung Diseases, Senotherapy for Lung Disease, Progress in the Development of Kinase Inhibitors for Treating Asthma and COPD, Prospects for Non-Antimicrobial Macrolides in Asthma and COPD, Delivery Technology of Inhaled Therapy for Asthma and COPD, and more.

Imaging in Virus Research, Volume 116 in the Advances in Virus Research series highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Topics of interest in this release include Recent developments of advanced fluorescence microscopy methods for biological applications, Fluorescence microscopy to image virus entry: Probing different angles, RSV and cytoplasmic inclusion bodies, Advanced Imaging of HIV-1 fusion and virus-host lipid interactions, Spatiotemporal orchestration of virus morphogenesis, Imaging applied to study interactions between poxviruses and their host cells, Viral capsid structures, Tissue Clearing and 3D-Imaging of Virus Infections, and much more.

Entrepreneurship with Microorganisms explains both the basic science and applications of microbiology and bio-resource technology, shining a special emphasis on its entrepreneurial applications. By focusing on basic principles, current research, and global trends, this comprehensive book provides a critical resource and serves as a complete one-stop source for undergraduate and graduates in microbiology, food, agricultural science, medical science, and industrial microbiology biotechnology. In addition, this book will be helpful in the creation of economic (commercial) value of the microorganism(s) based products and technologies as well as opportunities for new jobs at the global level.

Inoculating Cities: Case Studies of the Urban Response of the COVID-19 Pandemic uses detailed case studies to document and describe how cities located in high, middle and low-income countries responded to the COVID-19 pandemic. City governments and municipal authorities exist and operate in extremely varied contexts (i.e., socioeconomic, demographic, legal and governance, etc.) and intentionally documenting the experiences in these different contexts provides guidance to decision-makers for future preparedness and response activities. This volume highlights the innovative solutions throughout the pandemic as described by the people who designed and implemented pandemic response efforts in their cities. In addition, it identifies successful models that can be adopted in the future by city leaders around the world.

Vegetable Oil Based Polymers and Their Surface Applications presents detailed coverage of principles, preparation methods and novel surface uses of vegetable oil based polymers. This comprehensive, state-of-the-art book follows the journey of vegetable oils from seeds to surfaces in a range of advanced applications. Opening chapters discuss theory, principles and characterization techniques while other sections present concepts on the preparation of different polymer types based on vegetable oil. The final section of the book provides extensive coverage of applications, enabling the preparation of vegetable oil based polymers for a range of products and industries. This is a valuable resource for researchers, scientists, and advanced students in polymer chemistry, surfaces and coatings, natural polymers, materials chemistry, chemical engineering and plastics engineering. In an industrial setting, this book supports R&D professionals, scientists, and engineers interested in developing innovative biobased materials for a range of applications, including automotive and aerospace, packaging, cosmetics, pharmaceuticals, biomedicine and consumer goods.

The Immunological Synapse - Part B, Volume 178 in the Methods in Cell Biology series provides state-of-the-art methods for the study of the immunological synapse. This first volume covers various aspects on T cell and natural killer (NK) cell synapses, including imaging polarized granule release using TIRF microscopy, analysis of actin reorganization and centrosome polarization, redirected degranulation, live cell-imaging to quantify cytotoxic and chemotactic dynamics, quantification of interactions between APCs and T cells, assessment of membrane lipid state at the immunological synapse, proteomic analysis and imaging of NK-tumor cell interaction, evaluating natural killer cell effector functions against breast cancer cells derived from human tumor tissue, evaluation of chimeric antigen receptor (CAR)-modified cell immunological synapse quality using the glass-supported planar lipid bilayer, and monitoring potency of therapeutic CAR T cells. It also includes one chapter on quantification of lymphocytic choriomeningitis virus specific T cells and LCMV viral titers, and one chapter on the murine antibody-dependent cellular phagocytosis assay.

Senescence and Mitochondria Targeted Senotherapeutics, Volume 136 offers updates on this unique topics, with chapters covering Cellular Senescence in Aging: Molecular Basis, Implications and Therapeutic Interventions, Mitochondria-associated Cellular Senescence Mechanisms: Biochemical and Pharmacological Perspectives, Mitochondria in cell senescence: Friend or Foe?, The role of mitochondria and mitophagy in cell senescence, Small molecules targeting mitochondrial dysfunction for potential senotheraputics, Senolytic and senomorphic interventions to defy senescence-associated mitochondrial dysfunction, Mitochondrial targeting peptides and probes, Mitochondria-derived peptides in healthy ageing and therapy of age-related diseases, and much more. Other sections cover Targeting of mitostasis-proteostasis axis by antioxidant polysaccharides in neurodegeneration, Phytotherapeutic targeting of the mitochondria in neurodegenerative disorders, Melatonin as mitochondria-targeted drugs, Coenzyme Q-related compounds to maintain healthy mitochondria during aging, Changing ROS, NAD and AMP: a path to longevity via mitochondrial therapeutics, and more.

Advances in Botanical Research Volume 108: Ozone Pollution and Plant Health: Understanding the Impacts and Solutions for Sustainable Agriculture provides a comprehensive overview of the harmful effects of tropospheric ozone (O3) pollution on crop productivity, with a focus on how it is measured and modeled under climate change scenarios. The book discusses the sources of O3 pollution, including anthropogenic precursor gases, and how O3 exposure can impair photosynthesis, reduce gas exchange, induce early leaf senescence, and hamper growth in natural vegetation and crops. The book highlights how O3 interacts with plant physiology and metabolism, including through the activation of signal transduction pathways, changes in phytohormone signaling, and modulation of reactive oxygen species (ROS) generation and signaling. The book also explores the experimental and modeling methods used to assess the effects of O3 on crops, with a focus on studies conducted in Asia. The book emphasizes the importance of understanding the implications of ozone pollution for ensuring food security and protecting human and environmental health and suggests strategies such as using ozone-resistant cultivars of plants and crops. Additionally, the book discusses the broader context of air pollution and its impact on crop productivity, including the effects of other air pollutants on plants and crops and the need for mitigation strategies and policies to address agricultural losses. This book is essential reading for early-career researchers, sustainable agriculture practitioners, and policymakers interested in understanding the complex interactions between ozone pollution and plant productivity and finding solutions to mitigate the detrimental effects of ozone pollution on crops in a changing climate.