Books published by Elsevier Science Publishing Co Inc

Modelling of Chemical Process Systems gives readers a feel for multiscale modeling. The book starts with the history of modeling and its usefulness, describing modeling steps in detail. Examples have been chosen carefully from both conventional chemical process systems to contemporary systems, including fuel cell and micro reforming processes. Each chapter is accompanied by a case study that explains the step-by-step modeling methodology. The book also introduces the application of machine learning techniques to model chemical process systems.When combined, the information in the book makes it an indispensable reference for academics and professionals working in modeling and simulation.

Today, the pressure on healthcare costs and resources is increasing, and especially for biopharmaceuticals that require parenteral administration, the inherent complex and invasive dosing procedure adds to the demand for efficient medical management. In light of the COVID-19 pandemic the value of drug delivery technologies in enabling a flexible care setting is broadly recognized. In such a setting, patients and their caregivers can choose the place of drug administration based on individual preferences and capabilities. This includes not only dosing in the clinic but also supervised at-home dosing and self-administration for eligible patients. Formulation and Device Lifecycle Management of Biotherapeutics: A Guidance for Researchers and Drug Developers covers the various aspects of improving drug delivery of biological medicines with the ultimate goal to reduce dosing complexity associated with parenteral administration and, thus, enhance patient experience and drug administration-related healthcare capacity. The target audience are multidisciplinary researchers and drug developers in the pharmaceutical industry, biotech companies, and academia involved in formulation and device development. This includes pharmacology and medical experts in charge of generating nonclinical and clinical data to support approval of novel dosing regimens, and drug delivery scientists and engineers responsible for technical particulars of product optimizations. Moreover, professionals in market access and commercial functions are expected to benefit from the discussions about the impact of patient and healthcare provider needs and country-specific reimbursement models on realizing a truly convenient and cost and resource efficient drug delivery solution.

Handbook on the Toxicology of Metals, Fifth Edition, Volume I: General Considerations is the first volume of a two-volume work that gives an overview and covers topics of general importance including reviews of various health effects of trace metals. The book emphasizes toxic effects in humans, along with discussions on the toxic effects of animals and biological systems in vitro when relevant. The book has been systematically updated with the latest studies and advances in technology and contains several new chapters. As a multidisciplinary resource that integrates both human and environmental toxicology, the book is a comprehensive and valuable reference for toxicologists, physicians, pharmacologists, and environmental scientists in the fields of environmental, occupational and public health.

Fundamentals of Wind Farm Aerodynamic Layout Design, Volume Four provides readers with effective wind farm design and layout guidance through algorithm optimization, going beyond other references and general approaches in literature. Focusing on interactions of wake models, designers can combine numerical schemes presented in this book which also considers wake models¿ effects and problems on layout optimization in order to simulate and enhance wind farm designs. Covering the aerodynamic modeling and simulation of wind farms, the book's authors include experimental tests supporting modeling simulations and tutorials on the simulation of wind turbines. In addition, the book includes a CFD technique designed to be more computationally efficient than currently available techniques, making this book ideal for industrial engineers in the wind industry who need to produce an accurate simulation within limited timeframes.

Emerging Freshwater Pollutants: Analysis, Fate and Regulations comprises of 20 chapters, all written by leading experts. This book is written in the most practical terms and is easy to understand, with numerous helpful examples and case studies and can be used as a practical guide and important educational tool on issues concerning freshwater emerging pollutants. The organisation of the book exposes the reader in logical succession to the full range of complex scientific and management aspects of emerging freshwater pollutants in the developing world. The book recognises that water chemistry, emerging freshwater pollutants and management are inter-dependent disciplines. The book covers (i) the different monitoring techniques, current analytical approaches and instrumental analyses, (ii) fate and occurrence of emerging pollutants in aquatic systems and (iii) management policies and legislations on emerging pollutants. Thus, subsequent chapters elucidate chemicals with pollution potential, multi-detection approaches to analysis of organic pollutants in water, microplastics effects and photochemical transformation of emerging pollutants in freshwater systems. Whereas, other chapters address oxidation of organic compounds in aquatic systems, biomonitoring systems for detection of toxic levels of water pollutants, and health aspects of water recycling practices. This book melds several different perspectives on the subject of freshwater emerging pollutants and shows the interrelationships between the various professions that deal with water quality issues. Further, within the presentation of each separate chapter is discussion of how the various scientific and management aspects of the subject interrelate.

Energy Democracies for Sustainable Futures explores how our dominant carbon and nuclear energy assemblages shape conceptions of participation, risk, and in/securities, and how they might be reengineered to deliver justice and democratic participation in transitioning energy systems. Chapters assess the economies, geographies and politics of current and future energy landscapes, exposing how dominant assemblages (composed of technologies, strategies, knowledge and authorities) change our understanding of security and risk, and how they these shared understandings are often enacted uncritically in policy. Contributors address integral relationships across the production and government of material and human energies and the opportunities for sustainable and democratic governance. In addition, the book explores how interest groups advance idealized energy futures and energy imaginaries. The work delves into the role that states, market organizations and civil society play in envisioned energy change. It assesses how risks and security are formulated in relation to economics, politics, ecology, and human health. It concludes by integrating the relationships between alternative energies and governance strategies, including issues of centralization and decentralization, suggesting approaches to engineer democracy into decision-making about energy assemblages.

The Optimum-Path Forest (OPF) classifier was first published in 2008 in its supervised and unsupervised versions with applications in medicine and image classification. Since then, it has expanded to a variety of other applications such as remote sensing, electrical and petroleum engineering, and biology. In recent years, multi-label and semi-supervised versions were also developed to handle video classification problems. The book presents the principles, algorithms and applications of Optimum-Path Forest, giving the theory and state-of-the-art as well as insights into future directions.

Energy Storage for Multi-generation: Desalination, Power, Cooling and Heating Applications is designed to help readers implement and manage highly-efficient energy storage enabled industrial processes. The book provides an overview on energy storage technologies, recent trends around the world, and a discussion on the sustainability components of energy storage in different applications. Case studies for integrated power-water production schemes integrated with energy storage are also included, along with tactics to critically evaluate drivers that influence energy storage integration into power-water production schemes, including desalination, tri-generation and poly-generation concepts and configurations. This book will provide all engineers and researchers a better understanding of the application of renewable energy in desalination and the thermodynamic processes and laws involved.

Machine Learning and Artificial Intelligence in Radiation Oncology: A Guide for Clinicians is designed for the application of practical concepts in machine learning to clinical radiation oncology. It addresses the existing void in a resource to educate practicing clinicians about how machine learning can be used to improve clinical and patient-centered outcomes. This book is divided into three sections: the first addresses fundamental concepts of machine learning and radiation oncology, detailing techniques applied in genomics; the second section discusses translational opportunities, such as in radiogenomics and autosegmentation; and the final section encompasses current clinical applications in clinical decision making, how to integrate AI into workflow, use cases, and cross-collaborations with industry. The book is a valuable resource for oncologists, radiologists and several members of biomedical field who need to learn more about machine learning as a support for radiation oncology.

Rainfall: Physical Process, Measurement, Data Analysis and Usage in Hydrological Investigations integrates different rainfall perspectives, from droplet formation and modeling developments to the experimental measurements and their analysis, to application in surface and subsurface hydrological investigations. Each chapter provides an updated representation of the involved subject with relative open problems and includes a case study at the end of the chapter. The book targets postgraduate readers studying meteorology, civil and environmental engineering, geophysics, agronomy and natural science, as well as practitioners working in the fields of hydrology, hydrogeology, agronomy and water resource management.

Cyclic Vomiting Syndrome and Cannabinoid Hyperemesis comprehensively reviews the clinical features and pathophysiology of cyclic vomiting syndrome (CVS) and cannabinoid hyperemesis syndrome (CHS). This book differentiates the clinical presentation of CVS and CHS from other vomiting syndromes and provides the information necessary to diagnose and effectively treat these disorders. Compiled by expert CVS/CHS clinicians and written by physicians and researchers from several disciplines, this reference provides the most updated, evidence-based approaches, and summarizes the latest research on CVS/CHS. Important topics such as the neural systems that drive nausea and vomiting, clinical features of CVS/CHS including its subtypes, insights into pathogenesis, as well as the curious association of hot-water bathing associated with both of these disorders are all explored. This is a must-have reference for residents and fellows in training, as well as busy clinicians who care for patients with CVS and CHS across multiple care settings including ambulatory clinics, the emergency department, hospitals, and substance use/abuse treatment centers. It is also a useful reference for investigators with an interest in these vomiting disorders.

Climate Change in the Anthropocene reviews current science on anthropogenic sources and projections for climatic change. Written in a clear and accessible style, the book covers this rapidly changing field, including the drivers of climate change, the physics and chemistry behind the science of climate change, paleoclimates, climate variables, a comparison of global warning of 1.5° vs 2°C and the impacts of these climatic changes both at a global and a U.S. regional level. Infographics throughout help to explain concepts in a visual way, providing users with a better understanding of climate change.  In addition, the book is ideal for advanced researchers who need to explain the underpinning science of climate change for grant applications and working with policy experts, etc. This is an essential book for anyone whose work is impacted by climate change in the earth and environmental sciences.

Molecular Dynamic Simulation: Fundamentals and Applications explains the basic principles of MD simulation and explores its recent developments and roles in advanced modeling approaches. The implementation of MD simulation and its application to various aspects of materials science and engineering including mechanical, thermal, mass transportation, and physical/chemical reaction problems are illustrated. Innovative modeling techniques that apply MD to explore the mechanics of typical nanomaterials and nanostructures and to characterize crystalline, amorphous, and liquid systems are also presented. The rich research experience of the authors in MD simulation will ensure that the readers are provided with both an in-depth understanding of MD simulation and clear technical guidance.

Reliability and Probabilistic Safety Assessment in Multi-Unit Nuclear Power Plants presents the risk contributions from single and multi-unit Nuclear Power Plants to help aggregate the risks that may arise due to applicable hazards and operating states. The book combines the key features of multi-unit risk assessment in one resource, reviewing the practices adopted in various countries around the globe to exemplify the dependencies between units on a site. These dependencies include multi-unit interactions, environmental stresses, the sharing of systems, and the sharing of human resource in a control room, factors which can all introduce an increase potential for heightened accident conditions. This book helps readers systematically identify events and evaluate techniques of possible accident outcomes within multi-units. It serves as a ready reference for PSA analysts in identifying a suitable site and the sharing of resources, while carrying out multi-unit risk assessments to ensure the safety of the public and the environment. It will also be valuable for nuclear researchers, designers and regulators of nuclear power plants, nuclear regulatory agencies, PSA engineers and practicing safety professionals.

Balancing Greenhouse Gas Budgets: Accounting for Natural and Anthropogenic Flows of CO2 and other Trace Gases provides a synthesis of greenhouse gas budgeting activities across the world. Organized in four sections, including background, methods, case studies and opportunities, it is an interdisciplinary book covering both science and policy. All environments are covered, from terrestrial to ocean, along with atmospheric processes using models, inventories and observations to give a complete overview of greenhouse gas accounting. Perspectives presented give readers the tools necessary to understand budget activities, think critically, and use the framework to carry out initiatives.

Desalination Technologies: Design and Operation sets the scene for desalination technologies as a long-term solution to freshwater demand by analyzing the current demand for water, available water resources and future predicted demand. The book captures recent developments in thermal desalination (multistage flash desalination, multi-effect evaporation, vapor compression), membrane desalination (forward osmosis, reverse osmosis, pressure retarded, electrodialysis, membrane distillation, ultra-, nano-, and micro-filtration), and alternative processes such as freezing and ion exchange. Both dynamic and steady state models (from short cut, simple, to detail) of various desalination processes are discussed. The book is intended for (under)graduate students in chemical engineering and postgraduate researchers and industrial practitioners in desalination.

A New History of Vaccines for Infectious Diseases: Immunization - Chance and Necessity covers the developments of vaccines and how they have obliterated many fatal diseases and infections over time. The book treads a neutral path but does not avoid discussion. As uncertainty in the outcome of vaccination can only be determined by experiment, the path to vaccine development has been scientifically complex because the immune system and the manner in which humans respond to infection is variable and complex.  Finally, the book describes the risks and benefits of vaccines in a visibly objective manner.

Shows how to develop and make efficient use of resources, and provides information to those tasked with setting up and delivering simulation facilities for medical, clinical and related purposes, and the development and delivery of simulation-based education programs.