Books published by Elsevier Science Publishing Co Inc

Fast and Effective Embedded Systems Design, Third Edition is a fast-moving introduction to embedded systems design, applying the innovative Arm mbed "ecosystem," including both hardware components and its web-based development environment. Minimal background knowledge is needed to start. Each chapter introduces a major topic in embedded systems and proceeds as a series of practical experiments. A "learning through doing" strategy is adopted, with the underlying theory being introduced alongside. C/C++ programming is applied, with a step-by-step approach which allows you to get coding quickly. Once the basics are covered, the book progresses to some hot embedded topics - intelligent instrumentation, Bluetooth LE, Zigbee, real-time programming, and the Internet of Things.In this new edition all code is refreshed to match the new mbed operating system, and much new code is introduced. The principles of real-time operating systems are explained, and the capabilities of the mbed RTOS are clearly demonstrated. This third edition will readily form the basis of introductory and intermediate university or college courses in embedded systems.

Biocontamination Control for Pharmaceuticals and Healthcare, Second Edition outlines a biocontamination strategy that tracks bio-burden control and reduction at each transition in classified areas of a facility. The first edition of the book covers many of the aspects of the strategy, but the new official guidance signals that a roadmap is required to fully comply with its requirements. Completely updated with the newest version of the EU-GPM (EN17141), this new edition expands coverage of quality risk management and contains completely new examples to help professionals bridge the gap between regulation and implementation. This book offers professionals in pharma quality control and related areas guidance on building a complete biocontamination strategy.

Reproducibility in Biomedical Research: Epistemological and Statistical Problems, Second Edition explores the ideas and conundrums inherent in scientific research. This second edition addresses new challenges to reproducibility in biosciences, namely reproducibility of machine learning Artificial Intelligence (AI), reproducibility of translation from research to medical care, and the fundamental challenges to reproducibility. All current chapters are expanded to cover advances in the topics previously addressed. This book provides biomedical researchers with a framework to better understand the reproducibility challenges in the area. Newly introduced interactive exercises and updated case studies help students understand the fundamental concepts involved in the area.

Emery and Rimoin¿s Principles and Practice of Medical Genetics and Genomics: Developmental Disorders, Seventh Edition is distinguished as the ultimate resource for clinicians integrating genetics into medical practice. This updated edition includes the latest information on seminal topics such as prenatal diagnosis, genome and exome sequencing, public health genetics, genetic counseling, and management and treatment strategies. This comprehensive yet practical resource emphasizes theory and research fundamentals related to applications of medical genetics across the full spectrum of inherited disorders and applications in medicine more broadly. Users will find comprehensive sections on medical genetics applied to a range of developmental disorders and an emphasis on understanding the genetic mechanisms underlying these disorders, diagnostic approaches, and therapeutics that make use of current genomic technologies and translational studies. Updated chapters on human developmental genetics as well as the genetics of sexual development, clefting, dental, and craniofacial syndromes, craniosynostosis, rasopathies, sex-chromosome abnormalities, and autosomal deletions, among other disorders are included.

Anatomy of Neuropsychiatry: The New Anatomy of the Basal Forebrain and Its Implications for Neuropsychiatric Illness, Second Edition presents the anatomical systems that take part in the scientific and clinical study of emotional functions and neuropsychiatric disorders. The book discusses the limbic system¿the cortical and subcortical structures in the human brain involved in emotion, motivation, and emotional association with memory¿and how this is no longer a useful guide to psychiatric disorders. Newly revised, this book now includes chapters focusing on the anatomy of Basal Forebrain and Cerebellum Macrosystems and the role these macrosystems play in motion, emotion, and neuropsychiatric illnesses.This book will help reader develop an understanding of the gross anatomical organization of the human forebrain.

Introduction to Protein Mass Spectrometry, Second Edition provides a comprehensive overview of this increasingly important, yet complex, analytical technique. This book enables readers to understand how determinations about protein identity from mass spectrometric data are made. Coverage begins with the technical basics, including preparations, instruments, and spectrometric analysis of peptides and proteins, before exploring applied use in biological applications, bioinformatics, database, and software resources. This new edition is fully updated to include the latest developments in the field and will feature new content covering recent progress in the areas where there have been the most exciting advances. These include PNNL¿s multilevel-PCB-based SLIM realization, SLIM-Agilent QQQ field trials; employment of SLIM-IMS-cryo-IR combination in molecular structure determination; proximity-labelling mass spectrometry, and applications in neuroscience.

Dynamic Aquaria: Building and Restoring Ecosystems and the Biosphere, Fourth Edition demonstrates how the living systems modeling of aquatic ecosystems for ecological, biological, physiological research, and ecosystem restoration produce answers to very complex ecological questions. The book describes unique characteristics of water that have allowed carbon chemistry to flourish and evolve life over 4 billion years, along with current disruptions such as global warming, overfishing, and chemical pollution. New content in this edition includes the use of LED lighting, DNA sequencing in microcosm construction and analysis, and the expansion of the bioengineered tool Algal Turf Scrubbing (ATS) to combat global pollution problems.The book also features new information on marine calcification, research microcosms, thermogeography, and methods of water movement for minimizing plankton loss. It supports a deeper biological and ecological intelligence among the human population to better understand the processes behind environmental issues.

Soil Microbiology, Ecology, and Biochemistry, Fifth Edition addresses the increasingly important field of soil biota and their interactions in research and education. Soil biota are extremely important, and especially relevant to today¿s societal questions related to global change, ecosystem sustainability, and food security in our ever-changing environment. Revised by a group of world-renowned authors in many institutions and disciplines, this book relates breakthroughs in knowledge in this important field, along with its history and future applications. This new edition provides readable, practical, impactful information for many applied and fundamental disciplines. There is no other available volume on the topics covered that also integrates the concepts in a way that makes them useful to a broad group of readers.

Geophysical Data Analysis and Inverse Theory with MATLAB or Python, Fifth Edition is a revised and expanded introduction to inverse theory and tomography as it is practiced by geophysicists. The book demonstrates the methods needed to analyze a broad spectrum of geophysical datasets, with special attention given to those methods that generate images of the earth. Data analysis can be a mathematically complex activity, but the treatment in this volume is carefully designed to emphasize those mathematical techniques that readers will find the most familiar and to systematically introduce less-familiar ones. A series of "crib sheets" offer step-by-step summaries of methods presented. Utilizing problems and case studies, along with MATLAB and Python computer code and summaries of methods, the book provides professional geophysicists, students, data scientists and engineers in geophysics with the tools necessary to understand and apply mathematical techniques and inverse theory.

The Microbiology, Pathogenesis, and Zoonosis of Milk Borne Diseases offers comprehensive coverage of milk-borne infection, diagnosis, and treatment. With a strong focus on milk hygiene, zoonotic diseases, and the pathogenesis of milk-borne microbial agents, this book discusses various pathogenic diseases, evaluates the severity of diseases from milk and milk products, and describes remedial measures after the application of drugs.This book also introduces the reader to the microbiology, pathogenesis, and zoonosis of milk-borne diseases. It not only describes the general aspects of milk-borne zoonosis and prevention, but also covers risk analysis, assessment, practice, and quality management in milk hygiene.In 22 chapters, The Microbiology, Pathogenesis, and Zoonosis of Milk Borne Diseases provides researchers, academicians, industry professionals, and students with a better understanding on how to assess zoonotic diseases from milk-borne pathogens and address their clinical manifestations.

Data Fusion Techniques and Applications for Smart Healthcare covers cutting-edge research from both academia and industry, with a particular emphasis on recent advances in algorithms and applications that involve combining multiple sources of medical information. The book can be used as a reference for practicing engineers, scientists, and researchers, but it will also be useful for graduate students and practitioners from government and industry as well as healthcare technology professionals working on state-of-the-art information fusion solutions for healthcare applications.Medical data exists in several formats, from structured data and medical reports to 1D signals, 2D images, 3D volumes, or even higher dimensional data such as temporal 3D sequences. Healthcare experts can make auscultation reports in text format; electrocardiograms can be printed in time series format, X-rays saved as images; volume can be provided through angiography; temporal information by echocardiograms, and 4D information extracted through flow MRI.

Deep Learning Applications in Translational Bioinformatics, a new volume in the Advances in Ubiquitous Sensing Application for Healthcare series, offers a detailed overview of basic bioinformatics, deep learning, and various applications of deep learning in translational bioinformatics, including deep learning ensembles, deep learning in protein classification, detection of various diseases, prediction of antiviral peptides, identification of antibiotic resistance, computer aided drug design and drug formulation. This new volume helps researchers working in the field of machine learning and bioinformatics foster future research and development.

Introduction to Plasmas and Plasma Dynamics: With Plasma Physics Applications to Space Propulsion, Second Edition provides an accessible introduction to the understanding of the high temperature, ionized gases necessary to conduct research and develop applications related to plasmas. Thoroughly updated and expanded, this second edition is also amended for greater ease of use with the inclusion of self-study problems. New chapters addressing numerical methods in plasmas, the kinetic description and analysis of plasma, and the chemistry of the ionosphere open up this subject to a broader range of readers. Starting with the essential theory, this book goes on to describe relevant devices and mechanisms, before presenting a clear outline of the analysis and numerical details of plasma. The latest trends, concepts, and applications in plasma engineering are also addressed, including plasma formation and magnetic fusion, plasma thrusters and space propulsion.

Water-Soil-Vegetation Nexus and Climate Change presents an overview of research needs and approaches regarding water-soil-vegetation nexus and climate change. The book includes chapters discussing water budget and factors that affect hydrologic processes such as precipitation, runoff, infiltration, evapotranspiration, soil water, and groundwater, in addition to a focus on consumptive (e.g., domestic and irrigation) and non-consumptive (e.g., eco-environmental) water uses, and water shortage. Throughout the book, chapters specifically deal with the fundamental principles and also case studies, applications, and decision support tools that can be usable for developing practical management measures in sustaining our eco-environment and society by maintaining an optimal water-soil-vegetation equilibrium.Written with water resources students and professors in mind, this book will provide the reader with further knowledge on the water-soil-vegetation nexus and its connection to climate change.

Advanced Vaccination Technologies for Infectious and Chronic Diseases is a comprehensive guide that delves into the intricate details of vaccine design, development across various platforms, and the path to commercialization. This book provides an introductory overview of vaccines, covering various types, developmental methodologies, delivery systems, adjuvants, immunization, and measurement of vaccine efficacy. It also showcases examples of vaccine research efforts targeting infectious diseases, autoimmune disorders, and cancer. The book concludes by exploring cutting-edge advances in proteogenomics, immunopeptidomics, and future vaccine technologies. The primary objective of this book is to inform a broad scientific audience about the fundamental concepts underlying vaccine and immunology. Further, it serves as an invaluable reference for understanding the critical steps in the journey from discovery to regulatory processes for human clinical trials, addressing common misconceptions and presenting factual information about vaccinations. Advanced Vaccination Technologies for Infectious and Chronic Diseases is a requisite reference for occupational health professionals whose roles involve supervision of immunization programs such as those working within the National Health Service, some sectors of higher education, or the pharmaceutical industry. It also caters to those researchers engaged in vaccine development and all who want to learn the processes involved from laboratory research to final product.

Recent advances in pharmacology and brain stimulation have led to the development of novel treatments for psychiatric disorders. These new advances have led to the development of a new subspecialty, Interventional Psychiatry. Interventional Psychiatry: Road to Novel Therapeutics reviews all specialized treatments including device-based interventions such as electroconvulsive therapy (ECT), repetitive transcranial magnetic stimulation (rTMS), and deep brain stimulation (DBS). This book discusses the procedure-based pharmacologic interventions including ketamine infusion therapy and psychedelic therapies. Internationally contributed, this book outlines the state of the field, as well as implications for training and the role of the interventional psychiatrist in treatment teams.

Public Health and Toxicology Issues in Drug Research: Toxicity and Toxicodynamics, Volume Two examines implications on public health and the impact of pharmaceuticals, chemical and food toxicants, dietary phytochemicals, and medical treatments. The book cover topics on pharmacokinetics and toxicokinetics, such as population pharmacokinetics/toxicokinetics, the design of toxicokinetic studies, and the use of toxicokinetic data in preclinical safety assessments. In addition, it investigates the health effect caused by the bioaccumulation of pharmaceutical and personal care products and the impact of drug-induced toxicity on different systems of the body.Final sections discuss the mechanistic pathways of food toxicants and illustrate the molecular mechanisms of the chemopreventive role of dietary phytochemicals. Ethical, legal, societal, and professional issues in toxicology round off coverage, making this a valuable resource for anyone interested in learning more about the health impact and public health issues related to the toxicity of pharmaceuticals, dietary supplements, personal care products, and medical treatments.

Retinal and Choroidal Vascular Diseases of the Eye explores a variety of retinal and choroidal vascular diseases, covering their pathogenesis, clinical features, and management strategies. The book begins with an outline of the basic features of retinal and choroidal vasculature before moving on to imaging techniques. Chapters then delve into specific diseases and abnormalities, as well as vascular diseases that are associated with systemic inflammatory diseases. The book then moves onto considering vascular diseases associated with system conditions before considering vascular tumors. Recent innovations and upcoming treatment options are also explored for the various diseases throughout the book. This comprehensive reference provides a deep dive into vascular diseases of the eye, and is a must-have reference for ophthalmologists, medical and surgical retina specialists, and researchers in related fields.

Engineering Biology for Microbial Biosynthesis of Plant-Derived Bioactive Compounds will be of great interest to undergraduate and graduate students, scientists, researchers, and engineers who work on the microbial production of plant-derived bioactive compounds. As many plant-derived bioactive compounds are the foundation of effective drugs to cure diseases, it's important to understand the limits of their applications in drugs and other industries. With the development of synthetic biology and green biomanufacturing, the biosynthesis of complex bioactive compounds is possible. However, the engineering fundamentals for microbial biosynthetic of plant-derived bioactive compounds is vast.This book summarizes the engineering fundamental biotechnologies for microbial production of plant-derived bioactive compounds, allowing the content to be easily accessed. Coverage includes summaries of key achievements, identification of challenges, current approaches, tips and tricks, and helpful insights into critical bottlenecks.