Books published by Elsevier Science

Translational Orthopedics: Designing and Conducting Translational Research covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. Readers will come to fully understand important concepts, including case-control study, prospective cohort study, randomized trial, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in translational orthopedics, and know what is needed in collaboration. Further, this title is an indispensable tool in grant writing and funding efforts.The practical, straightforward approach helps the aspiring investigator navigate challenging considerations in study design and implementation. The book provides valuable discussions of the critical appraisal of published studies in translational orthopedics, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every Medical Researcher or Orthopedist who has ever had a good clinical idea but not the knowledge of how to test it.

Développez les compétences pour comprendre et soigner une grande diversité de patients ! Le Guide du professionnel de la santé sur la compétence culturelle, 2e édition explique la prestation de soins interculturels sûrs et efficaces. Ce livre met la théorie en pratique en commençant par un aperçu de la compétence culturelle clinique. Il montre comment appliquer la compétence culturelle à diverses populations et discute des considérations à prendre en travaillant avec des populations précises. Avec cette approche, vous développerez un ensemble de comportements, d'attitudes et de principes grâce auxquels vous travaillerez efficacement dans de nombreux milieux. Rédigé par une équipe d'auteur·e·s dirigée par Rani H. Srivastava, ce guide améliorera votre prise en charge des Autochtones, des membres de la communauté 2ELGBTQ+I, de personnes racisées, d'immigrants et de réfugiés. NOUVEAU! Cette édition est enrichie de nouveaux chapitres sur la santé des Autochtones, la diversité sexuelle et de genre, la santé des immigrants et des réfugiés, et la santé communautaire, ainsi que de nouveaux sujet tels que la sécurité culturelle, l'humilité culturelle, les impacts du racisme, le travail avec les interprètes, l'utilisation de la technologie et les soins palliatifs. NOUVEAU! UNIQUE! Des perspectives sur la compétence et la sécurité culturelles tout au long du texte vous permettront de fournir des soins culturellement sûrs et d'atteindre votre objectif d'apporter des soins équitables et appropriés sur le plan culturel. NOUVEAU! Une discussion sur les questions culturelles aborde le pouvoir, les privilèges, l'intersectionnalité, l'équité, la défense des droits et comment être un allié. NOUVEAU! Un contenu à jour comprend les dernières statistiques, lignes directrices, recherches, références et ressources. NOUVEAU! Le site Web Evolve améliore votre compréhension des questions de révision, des études de cas plausibles, et plus encore. Une approche UNIQUE aborde les populations telles que les travailleurs de la santé les rencontrent, et non en fonction d'étiquettes ethnoculturelles ou religieuses. Un style d'écriture accessible transmet l'information d'une manière équilibrée et concise pour les étudiants de premier et de deuxième cycle, ainsi que pour les professionnels de la santé. Une perspective multidisciplinaire grâce à des auteur·e·s qui représentent des disciplines de la santé et des identités culturelles diverses, qui travaillent en éducation ou en prestation de soins de la santé, et qui présentent des idées complexes de manière compréhensible et des idées controversées de manière transparente. Des encadrés Considérations culturelles dans les soins et Compétence culturelles en action qui associent la théorie à la pratique et invitent à une autoréflexion critique. Parmi les outils d'enseignement et d'apprentissage, chaque début de chapitre offre des objectifs d'apprentissage et des termes clés, chaque fin de chapitre propose des activités de groupe sont proposées, ainsi que des questions de révision et plus encore. NOUVEAU! Cette édition est enrichie de nouveaux chapitres sur la santé des Autochtones, la diversité sexuelle et de genre, la santé des immigrants et des réfugiés, et la santé communautaire, ainsi que de nouveaux sujet tels que la sécurité culturelle, l'humilité culturelle, les impacts du racisme, le travail avec les interprètes, l'utilisation de la technologie et les soins palliatifs. NOUVEAU! UNIQUE! Des perspectives sur la compétence et la sécurisation culturelles tout au long du texte vous permettront de fournir des soins culturellement sécuritaires et d'atteindre votre objectif d'apporter des soins équitables et appropriés sur le plan culturel. NOUVEAU! Une discussion sur les questions culturelles aborde le pouvoir, les privilèges, l'intersectionnalité, l'équité, la défense des droits et comment être un allié. NOUVEAU! Un contenu à jour comprend les dernières statistiques, lignes directrices, recherches, références et ressources. NOUVEAU! Le site Web Evolve améliore votre compréhension des questions de révision, des études de cas plausibles, et plus encore.

**Selected for Doody's Core Titles® 2024 in Physical Therapy**With a focus on the normal and abnormal mechanical interactions between the muscles and joints of the body,?Neumann's Kinesiology of the Musculoskeletal System, 4th Edition provides a foundation for the practice of physical rehabilitation. This comprehensive, research-based core text explores kinesiology as it relates to physical rehabilitation in a clinically relevant and accessible manner. It presents the language of human movement - and acts as a bridge between basic science and clinical management. It helps clinicians effectively address the mechanical-based changes in movement across a person's lifespan, whether in the context of rehabilitation, recreation, or promotion of health and wellness. Full-color anatomic and kinesiologic illustrations clearly demonstrate the anatomy, functional movement, and biomechanical principles underlying movement and posture. An eBook version, included with print purchase, provides access to all the text, figures, and references, with the ability to search, customize content, make notes and highlights, and have content read aloud. The eBook included with print purchase also features multiple excellent videos of anatomic and kinesiologic principles, answers to study questions from the print book, and additional tables and figures. Evidence-based approach emphasizes the importance of research in PT decision-making. More than 900 high-quality illustrations provide visual accompaniments to clarify the material. Clinical Connections boxes at the end of each chapter highlight or expand upon a particular clinical concept associated with the kinesiology covered in the chapter. Special Focus boxes throughout the text provide numerous clinical examples to demonstrate why kinesiologic information is needed. Critical thinking questions for selected chapters reinforce the main concepts. UPDATED! Current, evidence-based content closes the gap in kinesiology and anatomy science with clinical practice. NEW! Additional Special Focus boxes and Clinical Connections boxes present kinesiology in a clinical context. UPDATED! Modified artwork and new figures visually reinforce key concepts. NEW! An eBook version, included with print purchase, provides access to all the text, figures, and references, with the ability to search, customize content, make notes and highlights, and have content read aloud. It also features videos, answers to study questions from the print book, and additional tables and figures.

OrthoBiologics provides state-of-the-art knowledge of current biologic therapies for a variety of orthopaedic conditions in a single source. The content is presented in a straightforward manner, including defining all currently available orthobiologic options, discussing processing characteristics and appropriate clinical use, and finally, summarizing clinical applications and outcomes as well as future potential directions. In addition to covering current approaches and applications, the editors aim for this book to present "best practices" for those practicing and researching orthopaedic pathologies and orthobiologic treatments, including blood and cellular based therapies. The editors are world-renown experts in the field and this book fills a gap in the market.

Diagnosis and Treatment of Infectious Diseases summarizes practical content in infectious diseases using keys topics for better coding and grasping of material. The book's author uses his experience from over 15 years of teaching and working in infectious diseases in more than ten hospitals with thousands of patients as a backdrop. All of its contents use a clinical perspective for a wide range of audiences, such as medical students, general practitioners, nurses, and others. As infectious diseases are among the most common diseases, and a cause of death in many societies, they can create health challenges in developed and developing countries.Medical students have a limited time for infectious diseases rotation in their curriculum and may not learn many infectious diseases syndromes during their entire medical course. Also, due to the high volume of infectious disease subjects in textbooks which overlap symptoms and signs of many microorganisms, they may forget some of the materials. Therefore, access to a comprehensive compact book such as this one seems necessary for any medical staff.

Design and Analysis of Liquid Hydrogen Technologies: Liquefaction, Storage and Distribution offers readers a comprehensive guide to the development, analysis, design, and assessment methodologies for liquid hydrogen. From the fundamentals to the latest developments and current applications, the book provides an extensive and systematic discussion of the design, simulation, and techno-economic analysis methodologies that is supported by practical examples, verified codes, and innovative process designs. The book provides a comprehensive overview of the liquid hydrogen economy that is followed by advanced thermoeconomic, exergoeconomic, optimization, and dynamic simulation models that are essential for current and future LH2 technologies.Readers will find this to be a valuable resource for students, researchers, scientists, and engineers working in the hydrogen economy or involved in the processing, design, manufacturing, quality control, reliability, safety, systems, and testing of cryogenic refrigeration and liquid hydrogen production, storage, and transportation.

Ceramic matrix composites (CMCs) have proven to be useful for a wide range of applications because of properties such as their light weight, toughness and temperature resistance. Advances in ceramic matrix composites summarises key advances and types of processing of CMCs.After an introductory chapter, the first part of the book reviews types and processing of CMCs, covering processing, properties and applications. Chapters discuss nanoceramic matric composites, silicon carbide-containing alumina nanocomposites and advances in manufacture by various infiltration techniques including heat treatments and spark plasma sintering. The second part of the book is dedicated to understanding the properties of CMCs with chapters on Finite Element Analysis, tribology and wear and self-healing CMCs. The final part of the book examines the applications of CMCs, including those in the structural engineering, nuclear and fusion energy, turbine, metal cutting and microelectronics industries.Advances in ceramic matrix composites is an essential text for researchers and engineers in the field of CMCs and industries such as aerospace and automotive engineering.Reviews types and processing of CMCs, covering processing, properties and applications

Intelligent Fractal-Based Image Analysis: Application in Pattern Recognition and Machine Vision provides insights into the current strengths and weaknesses of different applications as well as research findings on fractal graphics in engineering and science applications. The book aims to improve the exchange of ideas and coherence between various core computing methods and highlights the relevance of related application areas for advanced as well as novice-user application. The book presents core concepts, methodological aspects, and advanced feature opportunities, focusing on major, real-time applications in engineering and health science. It will appeal to researchers, data scientists, industry professionals, and graduate students. Fractals are infinite, complex patterns used in modeling physical and dynamic systems. Fractal theory research has increased across different fields of applications including engineering science, health science, and social science. Recent literature shows the vital role fractals play in digital image analysis, specifically in biomedical image processing. Fractal graphics is an interdisciplinary field that deals with how computers can be used to gain high-level understanding from digital images. Integrating artificial intelligence with fractal characteristics has resulted in new interdisciplinary research in the fields of pattern recognition and image processing analysis.

Drug-delivery Systems of Phytochemicals as Therapeutic Strategies in Cancer Therapy elucidates the importance of various phytochemicals in cancer therapy and explains various routes/methods to deliver phytochemicals for overcoming the problems associated with delivery systems in cancer treatment. Several nanotechnological methods are presented to enhance drug solubility, sustainability, bioavailability, and gastrointestinal permeability of these phytochemicals. Current understanding of the relevant information presented on therapeutic strategies in cancer therapy fulfils the requirements of oncologists, molecular biologists, pharmacologist and related researchers who want to work in the areas of drug development targeting phytochemicals for cancer therapy.

Proteomics, Multi-Omics and Systems Biology in Optic Nerve Regeneration is a comprehensive reference that covers all vistas of standardization of axon regeneration, as well as all multi-omics and system level data and integration tools. By adopting a translational approach, the book bridges current research in the field to clinical applications, and readers can expect to learn standardization approaches for axon regeneration, multi-omics datasets, different databases, search engines, multiple dataset integrative tools, pathway convergence approaches and tools, outcome and outcome measures that unify bench research with clinical outcome.The axon regeneration from existing neurons in central nervous system (CNS) have become a potential possibility in the last decade. The potential possibility of long-distance axon growth has opened the possibility of re-connectivity of axons of retinal ganglion cell neurons within the lateral geniculate nucleus in the brain. The long-distance axon regeneration and re-connectivity is a promise to restore lost vision in the optic nerve. Further, long-distance regeneration and re-innervation is equally helpful for other fields such as spinal cord injuries.

Technical Organic and Inorganic Fibres from Natural Resources focuses on recent advances in the synthesis, processing, characterization, and application of non-textile fibers. The book provides a general introduction to the uses of natural fibers in technical textile applications while also reviewing the latest technical methods for producing these high-performance materials. As the textile industry is focused on finding alternative green fibers with the aim of providing high quality products which are fully recyclable and biodegradable, natural fibers from renewable sources play an increasingly important role in the industry due to their unique properties and functionality.

Artificial intelligence in healthcare has become one of the best assisting techniques for clinicians in proper diagnosis and surgery. In biomedical applications, artificial intelligence algorithms are explored for bio-signals, such as electrocardiogram (ECG/EKG), electrooculogram (EOG), electromyogram (EMG), electroencephalogram (EEG), blood pressure, heart rate, and nerve conduction, and for bio-imaging modalities, such as computed tomography (CT), cone-beam computed tomography (CBCT), and MRI (magnetic resonance imaging). Advancements in artificial intelligence and big data have increased the development of innovative medical devices in healthcare applications. Advances in Artificial Intelligence: Biomedical Engineering Applications in Signals and Imaging provides an overview of arti­ficial intelligence in biomedical applications, including both bio-signals and bio-imaging modalities. The chapters contain a mathematical formulation of algorithms and their applications in the biomedical ­ eld, including case studies. Biomedical engineers, advanced students, and researchers can use this book to apply their knowledge in artificial intelligence-based processes to biological signals, implement mathematical models and advanced algorithms, and develop AI-based medical devices.

In this issue of Dermatologic Clinics, guest editor Dr. Hassan Galadari brings his considerable expertise to the topic of Hot Topics in Cosmetic Dermatology. Top experts cover key topics such as neurotoxin in the lower third of the face; chemical peels in the treatment of melasma; management of under eye darkness and wrinkles; facial overfilled syndrome; the needle vs. cannula debate in soft tissue augmentation; achieving the attractive Asian midface profile with hyaluronic acid-based fillers; and more.Contains 17 relevant, practice-oriented topics including updates on lasers in dermatology; update in assessment and treatment of botulinum toxin in the upper face; cosmetic dermatology in skin of color; management of cellulite; the effect of cosmetic procedures on the youth; and more.Provides in-depth clinical reviews on hot topics in cosmetic dermatology, offering actionable insights for clinical practice.Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Adding Value to Fruit Wastes: Extraction, Properties, and Industrial Applications provides the latest technologies used in fruit waste to extract, isolate, and characterize functional, active compounds and their diversified pharmacological, food, agricultural, and industrial applications. Divided in three sections, the book explores emerging technologies for the extraction of functional components, discusses value-added components, and works as a guide to its applications. The book also covers fruit wastes for extracting starch to provide more cereal crops available as food, besides supporting the efficient utilization of fruit wastes to bring opportunities for extraction of functional components in a sustainable manner for food applications.Written by a team of experts in the field, this book provides technicians, researchers, food technology experts, food industry personnel, and academia with value addition to the fruit waste and a lot more opportunities for extraction of functional components in a sustainable manner for food applications.

Approximately 1 in 36 children in the United States will be diagnosed with autism spectrum disorder (ASD) and that number is expected to rise according to the CDC. Interventions based on the science of applied behavior analysis (ABA) are one of the most common interventions for autistic individuals. One of the biggest problems facing the field of ABA-based interventions is ineffectiveness of intervention approaches due to the rigid application of ABA-based interventions. Progressive Approach to Applied Behavior Analysis provides practicing behavior analysts (e.g., BCBAs, BCaBAs, RBTs) and other clinicians with an in-depth introduction to a Progressive Approach to ABA and how it applies to common teaching methods within ABA-based interventions. This includes research and guidelines for implementing a Progressive Approach to ABA, potentially increasing the likelihood of meaningful outcomes for individuals diagnosed with ASD. This will become the guide for practitioners on how to use clinical judgment and in-the-moment assessment across various procedures.

Traditional Starch Food Products: Application and Processing is the fourth volume of the "Underground Starchy Crops of South American Origin" book series. Organized in five volumes, this series brings information on the applied level of producing and using starch from a range of plants grown in tropical and subtropical areas that have South American origin. This book describes the use of starchy roots, tubers and rhizomes in food, medicine, local culture, and religion, emphasizing the vital roles they play in indigenous Andean or Amazonian communities, offering cultural identity and economic value. The book’s comprehensive exploration highlights the multifaceted world of underground starchy crops, emphasizing the challenges to their successful development and preservation. Edited by a team of experts with solid background on starch extraction research, these books are aimed at all those involved in research and development, new technology processes and quality control and legislation in the field of starch.

Thoracic surgery has evolved substantially in recent years, with tremendous advancements in minimally invasive surgical procedures, novel techniques for sublobar resection,  perioperative management, and more. Thoracic Surgery Atlas, 2nd Edition, written by Dr. Mark K. Ferguson, brings you fully up to date with all aspects of this fast-changing field. Comprehensive and highly illustrated, this general thoracic surgery text covers procedures involving all chest organs (lungs, esophagus, trachea, mediastinum, chest wall, and diaphragm), offering authoritative guidance on virtually any thoracic operation you're likely to perform-from cancer surgery to management of a variety of benign conditions, including esophageal disorders, empyema, tracheal stricture, and much more. Includes authoritative, experience-based observations to help guide you through details of complex procedures, avoid common problems, and manage complications when they occur. Features numerous high-quality, original color and tone drawings that depict the relevant anatomy and steps associated with each procedure. Expands coverage to include new areas of thoracic surgery, new and updated illustrations, and new content and references throughout. Provides new information on ERAS protocol summaries for perioperative care, consensus guidelines for essential steps in minimally invasive lung resection, new surgical approaches to mediastinal abnormalities, increased focus on VATS and robotic operations including uniportal surgery, new methods of treating thoracic outlet syndrome, new approaches to managing malignant ventricular arrhythmias through sympathectomy, more advanced techniques for pleurectomy for mesothelioma, and descriptions of a variety of newer muscle flaps for reconstruction. An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

Visualizing More Quaternions is a sequel to Dr. Andrew J. Hanson’s first book, Visualizing Quaternions, which appeared in 2006. This new volume develops and extends concepts that have attracted the author’s attention in the intervening 18 years, providing new insights into existing scholarship, and detailing results from Dr. Hanson’s own published and unpublished investigations relating to quaternion applications. Among the topics covered are the introduction of new approaches to depicting quaternions and their properties, applications of quaternion methods to cloud matching, including both orthographic and perspective projection problems, and orientation feature analysis for proteomics and bioinformatics. The quaternion adjugate variables are introduced to embody the nontrivial quaternion topology on the three-sphere and incorporate it into machine learning tasks. Other subjects include quaternion applications to a wide variety of problems in physics, including quantum computing, complexified quaternions in special relativity, and a detailed study of the Kleinian "ADE"discrete groups of the ordinary two-sphere. Quaternion geometry is also incorporated into the isometric embedding of the Eguchi-Hanson gravitational instanton corresponding to the k = 1 Kleinian cyclic group. Visualizing More Quaternions endeavors to explore novel ways of thinking about challenging problems that are relevant to a broad audience involved in a wide variety of scientific disciplines.

For more than 50 years, Dubois’ Lupus Erythematosus and Related Syndromes has been recognized internationally as the go-to clinical reference on lupus and other connective tissue diseases. From basic scientific principles to practical points of clinical management, the 10th edition provides extensive, authoritative coverage of systemic lupus erythematosus (SLE) and its related diseases in a logical, clearly written, user-friendly manner. It’s an ideal resource for rheumatologists and internal medicine practitioners who need a comprehensive clinical reference on all aspects of SLE, connective tissue diseases, and the antiphospholipid syndromes.Provides complete clinical coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education.Includes significant new content throughout: a new chapter on the endocrine system and hormones; newly distinct chapters on the heart and lung; new content on social disparities in lupus, clinical presentation of nephritis, and pulmonary hypertension; a new concluding chapter on future directions in the field; new basic science coverage of the microbiome, autoinflammatory, and monogenic lupus; and new coverage of diversity, inclusion, gender, compliance, and adherence.Offers a fresh perspective from two new associate editors and many new authors with representation from 30 countries.Contains an up-to-date overview of significant advances in cellular, molecular, and genetic technologies, including genetic advancements in identifying at-risk patients.Discusses the clinical management of related disorders such as Sjogren’s syndrome, scleroderma, polymyositis, and antiphospholipid syndrome (APS).Presents the knowledge and expertise of international contributors to provide new global perspectives on manifestations, diagnosis, and treatment.Features a vibrant, full-color format, with graphs, algorithms, differential diagnosis comparisons, new and improved figures, and schematic diagrams throughout.An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date.

Covering everything from preoperative evaluation to neonatal emergencies to the PACU, Coté, Lerman and Anderson’s A Practice of Anesthesia in Infants and Children, 7th Edition, features state-of-the-art advice on the safe, effective administration of general and regional anesthesia and sedation strategies for young patients. This text reviews underlying scientific information, addresses preoperative assessment and anesthesia management in detail, and provides guidelines for postoperative care, emergencies, and special procedures. Comprehensive in scope and thoroughly up to date, this edition delivers unsurpassed coverage of every key aspect of pediatric anesthesia.Presents must-know information on standards, techniques, and the latest advances in pediatric anesthesia from global experts in the field.Contains thoroughly updated content throughout, with new contributors to lend a fresh perspective, updated figures and tables, and the latest information on perioperative fluid management, pharmacology, interventional devices, resuscitation, and more.Covers key topics such as anesthetizing children with cancer, neonatal and pediatric emergencies, the obese child and bariatric surgery, interventional devices for children with congenital heart defects, cardiopulmonary resuscitation, simulation in pediatric anesthesia, patient safety and quality assurance, and more.Features an extensive video library of pediatric anesthesia procedures, particularly difficult airway management strategies, new positioning devices, cardiac assist devices in action, management of burn injuries, how to perform ultrasound-guided regional anesthesia blocks and techniques, and much more.Essentials chapters provide focused input from expert subspecialty pediatricians who share the latest information concerning hematology, pulmonology, oncology, hepatology, nephrology, and neurology.Includes a laminated pocket reference guide with essential, practical information, and key references at the end of each chapter that provide a quick summary for review.An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date.

Microbial Genomics: Clinical, Pharmaceutical and Industrial Applications focuses on the various applications of microbial genomics in clinical, pharmaceutical, and industrial fields. The book consists of four parts devoted to bacterial, viral, and fungal genomics, as well as their applications in clinical, pharmaceutical, and industrial fields. Chapters are written by experts in their respective disciplines and are tightly organized with an introduction to detailed descriptions, available software implementation, applications, advanced topics, summaries, analytic questions, exercises, and suggested readings. Throughout this book, the latest genomics and biotechnological developments and discoveries as well as open problems and future challenges on microbial genomics are highlighted. Readers will be introduced to state-of-the-art developments and trends of microbial genomics, its clinical, pharmaceutical, and industrial applications.

Machine Learning Applications in Industrial Solid Ash begins with fundamentals in solid ash, covering the status of solid ash generation and management. The book moves on to foundational knowledge on ML in solid ash management, which provides a brief introduction of ML for solid ash applications. The reference then goes on to discuss ML approaches currently used to address problems in solid ash management and recycling, including solid ash generation, clustering analysis, origin identification, reactivity prediction, leaching potential modelling and metal recovery evaluation, etc. Finally, potential future trends and challenges in the field are discussed. Offering the ability to process large or complex datasets, machine learning (ML) holds huge potential to reshape the whole status for solid ash management and recycling. This book is the first published book about ML in solid ash management and recycling. It highlights fundamental knowledge and recent advances in this topic, offering readers new insight into how these tools can be utilized to enhance their own work.

Metabolomics for Personalized Vaccinology provides insight into the importance of personalized vaccines in the clinical and research environments. It explores the development of personalized vaccines, which requires in-depth knowledge of the patient's health status, particularly the immune system, and on metabolomics, the closest indicator of the disease phenotype. Specifically, the book provides an understanding of how metabolomics might be employed in personalized vaccinology and how the metabolic pathway of the host's system is altered by vaccine administration.Over the past few years, researchers have published articles on personalized vaccines, but these are sparse. Therefore, compiling information on this topic gives the reader an overview of the progress of the field, despite being at its infancy.Metabolomics for Personalized Vaccinology is ideally suited for researchers and postgraduate students who are interested in clinical and nonclinical studies where metabolites are used for the identification of disease and therapeutic targets.

Functionalized Nanomaterials for Cancer Research: Applications in Treatments, Tools and Devices presents an in-depth and step-by-step description of knowledge on functionalized nanomaterials for cancer research, including treatment and future developments as well as their impact on patients’ overall outcomes. The book discusses functionalized nanoplatforms for cancer detection and imaging, interactions between nanomaterials and cancer cells, and drug resistant malignancies. The book's chapters are organized in a manner that can be readily adopted as sources for new and further studies by highlighting the main in vitro and in vivo nano-therapeutic achievements on cancer. Additionally, current trends on functionalized nanomaterials for cancer research and commercial scale opportunities are discussed. This is a valuable resource for researchers, oncologists, students, and members of the biomedical and medical fields who want to learn more about the potential of nanotechnology in cancer research and treatment.

Nanostructured Drug Delivery Systems in Infectious Disease Treatment explores a broad range of promising approaches for the treatment of infectious diseases using the latest advancements in nanomedical technologies. The book opens with an introduction about infectious diseases and global burdens. There is also specific discussion and assessment of the global impact of viruses with an emphasis on COVID-19, Zika, and Ebola. Subsequent chapters provide detailed information about various novel nanotherapeutic strategies used for delivering drugs for the treatment of various types of viral, bacterial, and fungal disorders. This will be a valuable resource for graduates, researchers, industry professionals, and anyone working to tackle the challenges of delivering drugs in a more targeted and efficient manner for the treatment of infectious diseases.

"This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all aspects of infectious diseases, including novel infections and lesser-known microorganisms, this volume incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Infectious Diseases is a visually stunning, one-stop resource for every practicing pathologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource"--

Inherited White Matter Disorders and Their Mimics, Volume 204 discusses where imaging abnormalities and pathology lie predominantly in the CNS white matter. Many acquired causes, such as multiple sclerosis, are readily diagnosed and familiar to the majority of neurologists. However, less common acquired causes and genetic disorders (the leukodystrophies and genetic leukoencephalopathies) often present a diagnostic challenge. The evaluation of patients with White matter disorders (WMDs) has evolved enormously in recent decades, due to advances in genetics, radiology, and the development of treatments for specific disorders. This book brings together WMD research, spanning basic science, molecular genetics, and clinical and radiological phenotyping.This volume presents both common WMDs and rare disorders according to their presentations or pathophysiology. Chapters lay out the clinical and radiological presentation of the disorder, followed by genetics and diagnostics, and finally discussion of pathophysiology and treatment. Chapter contain imaging, clinical pearls to diagnosis, and reference tables for genotype-phenotype correlation. For diagnostic work-up, easy to read algorithms are presented as well as clear guidance on indications for treatment, where applicable.

Computational Modeling Applications for Climate Crisis provides readers with innovative research on the applications of computational modeling to moderate climate change. The book begins with an overview and history of climate change, followed by several chapters covering the concepts of computational modeling and simulation, including parameters of climate change, modeling the effects of human activities, visualization tools, and data fusion for advanced modeling applications. It then proceeds to cover decision support systems, modeling of technological solutions for climate change, modeling of greenhouse gas emissions, tracking of climate factors, and modeling of earth resources. In the final chapters of the book, the authors cover nation-based outcomes, big data, and optimization solutions with real-world data and case studies. Climate change is one of the most pressing existential issues for humans and the planet, and this book covers leading-edge applications of computational modeling to the vast array of interdisciplinary factors and challenges posed by climate change. As life itself is a mixture of occurrences that can be mathematically modelled, it is important to work with specific parameters, which are critical for monitoring and controlling the dynamics of the earth, natural resources, technological factors, and human activities.

Treatment and Utilization of Combustion and Incineration Residues introduces state-of-art strategies for combustion and incineration solid residue management and utilization. The book also reviews current technologies for pollutant removal and control of combustion and incineration residues. Recycling ashes and slags in sustainable construction materials are also evaluated on environmental impacts and engineering values, and the use of different ashes and slags in cement clinker production is classified based on the sources and properties of the residues. In addition, the recovery of valuable metals and inorganic elements is also discussed.Finally, the book examines the latest understanding of reaction mechanisms of various treatment technologies, the future design of treatment technologies, and the actualization of sustainable management for combustion/incineration residues.