Books published by Elsevier Science

For more than 50 years, Dubois’ Lupus Erythematosus and Related Syndromes has been recognized internationally as the go-to clinical reference on lupus and other connective tissue diseases. From basic scientific principles to practical points of clinical management, the 10th edition provides extensive, authoritative coverage of systemic lupus erythematosus (SLE) and its related diseases in a logical, clearly written, user-friendly manner. It’s an ideal resource for rheumatologists and internal medicine practitioners who need a comprehensive clinical reference on all aspects of SLE, connective tissue diseases, and the antiphospholipid syndromes.Provides complete clinical coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education.Includes significant new content throughout: a new chapter on the endocrine system and hormones; newly distinct chapters on the heart and lung; new content on social disparities in lupus, clinical presentation of nephritis, and pulmonary hypertension; a new concluding chapter on future directions in the field; new basic science coverage of the microbiome, autoinflammatory, and monogenic lupus; and new coverage of diversity, inclusion, gender, compliance, and adherence.Offers a fresh perspective from two new associate editors and many new authors with representation from 30 countries.Contains an up-to-date overview of significant advances in cellular, molecular, and genetic technologies, including genetic advancements in identifying at-risk patients.Discusses the clinical management of related disorders such as Sjogren’s syndrome, scleroderma, polymyositis, and antiphospholipid syndrome (APS).Presents the knowledge and expertise of international contributors to provide new global perspectives on manifestations, diagnosis, and treatment.Features a vibrant, full-color format, with graphs, algorithms, differential diagnosis comparisons, new and improved figures, and schematic diagrams throughout.An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date.

Covering everything from preoperative evaluation to neonatal emergencies to the PACU, Coté, Lerman and Anderson’s A Practice of Anesthesia in Infants and Children, 7th Edition, features state-of-the-art advice on the safe, effective administration of general and regional anesthesia and sedation strategies for young patients. This text reviews underlying scientific information, addresses preoperative assessment and anesthesia management in detail, and provides guidelines for postoperative care, emergencies, and special procedures. Comprehensive in scope and thoroughly up to date, this edition delivers unsurpassed coverage of every key aspect of pediatric anesthesia.Presents must-know information on standards, techniques, and the latest advances in pediatric anesthesia from global experts in the field.Contains thoroughly updated content throughout, with new contributors to lend a fresh perspective, updated figures and tables, and the latest information on perioperative fluid management, pharmacology, interventional devices, resuscitation, and more.Covers key topics such as anesthetizing children with cancer, neonatal and pediatric emergencies, the obese child and bariatric surgery, interventional devices for children with congenital heart defects, cardiopulmonary resuscitation, simulation in pediatric anesthesia, patient safety and quality assurance, and more.Features an extensive video library of pediatric anesthesia procedures, particularly difficult airway management strategies, new positioning devices, cardiac assist devices in action, management of burn injuries, how to perform ultrasound-guided regional anesthesia blocks and techniques, and much more.Essentials chapters provide focused input from expert subspecialty pediatricians who share the latest information concerning hematology, pulmonology, oncology, hepatology, nephrology, and neurology.Includes a laminated pocket reference guide with essential, practical information, and key references at the end of each chapter that provide a quick summary for review.An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date.

Handbook of Translational Transcriptomics: Research, Protocols and Applications provides a comprehensive overview on the field of transcriptomics. The book begins with an overview of the past, present, and potential approaches in the field of transcriptomics, with discussions on choosing the correct approach based on the research needed. The book also highlights the pros and cons of each approach and explores techniques and protocols for investigating specific avenues, focusing on RNA sequencing, expression arrays, and gene expression. Sections on data analysis offer recommendations, guidelines, and approaches related to data interpretation.The book also considers the translation of transcriptomics to clinical application and applications in molecular diagnostics, biomarkers in medicine, and personalized medicine specific to oncology, as well as biotechnology for pharmaceutical research.

In Neuroscience Without Representations, an Open Access book, Oscar Vilarroya addresses the notion of "representation" as used in expressions like "neural representation" or "mental representation". This concept is fundamental in neuroscience, yet there remains no clear, universally accepted view on what it means for a nervous system to represent something, what constitutes a neural activity as a representation, and what is being re-presented. The book lays the foundation for a non-representational view of brain function. Building upon György Buzsáki’s critique of the theoretical framework underlying current cognitive neuroscience, Vilarroya argues that disciplines such as embodied and embedded cognition-collectively known as ‘4E cognition’-are driving a paradigm shift in our understanding of animal cognition. Rather than grounding cognition solely in representations, the author proposes an alternative: understanding cognition as enaction-the meaningful engagement of an organism to address situational requirements. The book supports this approach through detailed analyses of recent studies.

Microbial Genomics: Clinical, Pharmaceutical and Industrial Applications focuses on the various applications of microbial genomics in clinical, pharmaceutical, and industrial fields. The book consists of four parts devoted to bacterial, viral, and fungal genomics, as well as their applications in clinical, pharmaceutical, and industrial fields. Chapters are written by experts in their respective disciplines and are tightly organized with an introduction to detailed descriptions, available software implementation, applications, advanced topics, summaries, analytic questions, exercises, and suggested readings. Throughout this book, the latest genomics and biotechnological developments and discoveries as well as open problems and future challenges on microbial genomics are highlighted. Readers will be introduced to state-of-the-art developments and trends of microbial genomics, its clinical, pharmaceutical, and industrial applications.

Magnetoelectric Composites: Materials, Structures, and Applications, Second Edition summarizes the theory behind magnetoelectric phenomena and then introduces magnetoelectric materials and structures and the techniques used to fabricate and characterize them. Part two of the book looks at magnetoelectric devices: applications covered include magnetoelectric sensors, magnetoelectric antennas, transducers for energy harvesting, microwave and millimetre wave devices, and miniature magnetoelectric systems for biomedical applications. The final chapter discusses progress toward magnetoelectric memory.This new edition starts with the phenomena and theory of magnetoelectric materials in bulk laminates, thin-film heterostructures, and nanocomposites. On the magnetoelectric devices side, the contents have been significantly expanded to include energy harvesting, sensing, and magnetoelectric antennas. This book is suitable for materials scientists and engineers working on magnetoelectrics in academia and R&D.

Metabolomics for Personalized Vaccinology provides insight into the importance of personalized vaccines in the clinical and research environments. It explores the development of personalized vaccines, which requires in-depth knowledge of the patient's health status, particularly the immune system, and on metabolomics, the closest indicator of the disease phenotype. Specifically, the book provides an understanding of how metabolomics might be employed in personalized vaccinology and how the metabolic pathway of the host's system is altered by vaccine administration.Over the past few years, researchers have published articles on personalized vaccines, but these are sparse. Therefore, compiling information on this topic gives the reader an overview of the progress of the field, despite being at its infancy.Metabolomics for Personalized Vaccinology is ideally suited for researchers and postgraduate students who are interested in clinical and nonclinical studies where metabolites are used for the identification of disease and therapeutic targets.

Machine Learning Applications in Industrial Solid Ash begins with fundamentals in solid ash, covering the status of solid ash generation and management. The book moves on to foundational knowledge on ML in solid ash management, which provides a brief introduction of ML for solid ash applications. The reference then goes on to discuss ML approaches currently used to address problems in solid ash management and recycling, including solid ash generation, clustering analysis, origin identification, reactivity prediction, leaching potential modelling and metal recovery evaluation, etc. Finally, potential future trends and challenges in the field are discussed. Offering the ability to process large or complex datasets, machine learning (ML) holds huge potential to reshape the whole status for solid ash management and recycling. This book is the first published book about ML in solid ash management and recycling. It highlights fundamental knowledge and recent advances in this topic, offering readers new insight into how these tools can be utilized to enhance their own work.

Functionalized Nanomaterials for Cancer Research: Applications in Treatments, Tools and Devices presents an in-depth and step-by-step description of knowledge on functionalized nanomaterials for cancer research, including treatment and future developments as well as their impact on patients’ overall outcomes. The book discusses functionalized nanoplatforms for cancer detection and imaging, interactions between nanomaterials and cancer cells, and drug resistant malignancies. The book's chapters are organized in a manner that can be readily adopted as sources for new and further studies by highlighting the main in vitro and in vivo nano-therapeutic achievements on cancer. Additionally, current trends on functionalized nanomaterials for cancer research and commercial scale opportunities are discussed. This is a valuable resource for researchers, oncologists, students, and members of the biomedical and medical fields who want to learn more about the potential of nanotechnology in cancer research and treatment.

Nanostructured Drug Delivery Systems in Infectious Disease Treatment explores a broad range of promising approaches for the treatment of infectious diseases using the latest advancements in nanomedical technologies. The book opens with an introduction about infectious diseases and global burdens. There is also specific discussion and assessment of the global impact of viruses with an emphasis on COVID-19, Zika, and Ebola. Subsequent chapters provide detailed information about various novel nanotherapeutic strategies used for delivering drugs for the treatment of various types of viral, bacterial, and fungal disorders. This will be a valuable resource for graduates, researchers, industry professionals, and anyone working to tackle the challenges of delivering drugs in a more targeted and efficient manner for the treatment of infectious diseases.

"This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all aspects of infectious diseases, including novel infections and lesser-known microorganisms, this volume incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Infectious Diseases is a visually stunning, one-stop resource for every practicing pathologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource"--

Inherited White Matter Disorders and Their Mimics, Volume 204 discusses where imaging abnormalities and pathology lie predominantly in the CNS white matter. Many acquired causes, such as multiple sclerosis, are readily diagnosed and familiar to the majority of neurologists. However, less common acquired causes and genetic disorders (the leukodystrophies and genetic leukoencephalopathies) often present a diagnostic challenge. The evaluation of patients with White matter disorders (WMDs) has evolved enormously in recent decades, due to advances in genetics, radiology, and the development of treatments for specific disorders. This book brings together WMD research, spanning basic science, molecular genetics, and clinical and radiological phenotyping.This volume presents both common WMDs and rare disorders according to their presentations or pathophysiology. Chapters lay out the clinical and radiological presentation of the disorder, followed by genetics and diagnostics, and finally discussion of pathophysiology and treatment. Chapter contain imaging, clinical pearls to diagnosis, and reference tables for genotype-phenotype correlation. For diagnostic work-up, easy to read algorithms are presented as well as clear guidance on indications for treatment, where applicable.

Computational Modeling Applications for Climate Crisis provides readers with innovative research on the applications of computational modeling to moderate climate change. The book begins with an overview and history of climate change, followed by several chapters covering the concepts of computational modeling and simulation, including parameters of climate change, modeling the effects of human activities, visualization tools, and data fusion for advanced modeling applications. It then proceeds to cover decision support systems, modeling of technological solutions for climate change, modeling of greenhouse gas emissions, tracking of climate factors, and modeling of earth resources. In the final chapters of the book, the authors cover nation-based outcomes, big data, and optimization solutions with real-world data and case studies. Climate change is one of the most pressing existential issues for humans and the planet, and this book covers leading-edge applications of computational modeling to the vast array of interdisciplinary factors and challenges posed by climate change. As life itself is a mixture of occurrences that can be mathematically modelled, it is important to work with specific parameters, which are critical for monitoring and controlling the dynamics of the earth, natural resources, technological factors, and human activities.

Treatment and Utilization of Combustion and Incineration Residues introduces state-of-art strategies for combustion and incineration solid residue management and utilization. The book also reviews current technologies for pollutant removal and control of combustion and incineration residues. Recycling ashes and slags in sustainable construction materials are also evaluated on environmental impacts and engineering values, and the use of different ashes and slags in cement clinker production is classified based on the sources and properties of the residues. In addition, the recovery of valuable metals and inorganic elements is also discussed.Finally, the book examines the latest understanding of reaction mechanisms of various treatment technologies, the future design of treatment technologies, and the actualization of sustainable management for combustion/incineration residues.

Interfacial Science for Geosystems Engineers provides geoscientists the connections between the nano-scale physico-chemical interactions between fluids and minerals and the core/field-scale observations to manage energy extraction, water resources and subsurface storage, timely topics central to the energy transition. Packed with latest research and recent developments, chapter learning objectives, and illustrative diagrams, tables and charts throughout, this specialized volume will help geosystems engineers tackle the above challenges, by systematically going through the basics of surface and interfacial tension, capillarity, surfactants, surface free energy, adsorption, electrokinetics, colloidal stability, equilibrium and stability of thin liquid films, wettability, microemulsions, emulsions and foams, and polymers for subsurface applications. Useful as a teaching, training or reference text, Interfacial Science for Geosystems Engineers prepares today's subsurface scientists and engineers to tackle two pressing problems in the energy transition, by introducing recent developments on how to remove CO2 from our environment and how to wean ourselves off fossil energy while meeting growing energy demands.

Nanosensors in Healthcare Diagnostics examines the role of nanosensors in clinical microbiology, point-of-care sensing, clinical diagnostics, and therapy. This book addresses the concept of nanosensors and their utilization in healthcare diagnostics, and therapy. It covers the principles and mechanisms involved in nanosensor-based diagnostics platforms. It also discusses various approaches and techniques used in the preparation of nanosensors as well as the biomedical application of nanosensors in clinical diagnostics and their significance in the detection, treatment, and management of diseases. This book is a useful reference for researchers, graduate students, and industry professionals studying nanosensors in biological and medical sciences.

Developments in Food Quality and Safety Series is the most up-to-date resource covering trend topics such as Advances in the analysis of toxic compounds and control of food poisoning; Food fraud, traceability and authenticity; Revalorization of agrifood industry; Natural antimicrobial compounds and application to improve the preservation of food; Non-thermal processing technologies in the food industry; Nanotechnology in food production; and Intelligent packaging and sensors for food applications. Volume 4, Food Industry 4.0: Emerging Trends and Technologies in Food Production and Consumption covers several technologies (e.g., robotics, smart sensors, artificial intelligence, and big data) at different development and research levels in order to provide holistic multidisciplinary approaches that embrace simultaneously as many Industry 4.0 technologies as possible, reflecting the long journey of food from farm (or sea) to fork. Chapters explore automation, digitalization, and green technologies, besides food quality, food safety food traceability, processing and preservation 4.0. Topics such as smart sensors, artificial intelligence and big data revolution, additive manufacturing, and emerging food trends are also explored. The series is edited by Dr. José Manuel Lorenzo and authored by a team of global experts in the fields of Food Quality and Safety, providing comprehensive knowledge to food industry personals and scientists.

Biochar Production for Green Economy: Agricultural and Environmental Perspectives addresses the advancements and developments for the efficient diversification of biochar toward achieving improved agricultural and environmental benefits.  This comprehensive and cohesive volume is the first to address the potential multi-and transdisciplinary opportunities of effective biochar production and use. Including the potential applicability of not only crop waste biochar but weeds, agroforestry, agroindustry, municipal waste, as well chapters explore surface modified, enriched or tailored biochar for soil amendment, GHGs mitigation, bioremediation of organic, inorganic, metals and other emerging pollutants, as well as soil remediation. It also covers the trending multidisciplinary approaches of nanotechnology, surface chemistry and thermal decomposition advancements being adopted for capacity enhancement and versatile applicability in the field of agriculture, environment science and green energy synthesis. Composition and characteristics of tailored biochar, their interactions, and transformation into the soil and water ecosystem are illustrated. This book is a valuable resource for those pursuing biochar related areas as well as those seeking environmentally sustainable solutions to crop, soil or water issues.

Small Lungs and Obstructed Airways: Reassessing Chronic Obstructive Pulmonary Disease proposes an alternative perspective to current explanations for the distribution of chronic lung disease. The book considers the link between chronic respiratory disease and associated mortality with smaller lungs rather than obstructed airways and explores other factors contributing to poor lung health besides the current emphasis on the roles of air pollution, occupational exposures, and cardio-metabolic disease. It presents the findings of the Burden of Obstructive Lung Disease (BOLD) study, sharing new views on the prevalence of obstructive lung disease and risk factors across various global regions. Sections cover decreased lung function, including the prevalent views on the impact of both household and external air pollution, occupational exposure, and the prenatal and postnatal/childhood environment in the etiology of impaired lung function and COPD. The book then moves on to discussions on the impact poverty and nutrition has on lung health, sharing the findings of the BOLD study regarding its effect on lung function and risk of COPD in lower-income countries. The book closes with a chapter outlining the clinical and public health implications of the findings discussed in the book.

Energy Management in Homes and Residential Microgrids: Short-Term Scheduling and Long-Term Planning provides an in-depth exploration of Home Energy Management Systems (HEMS), with a focus on practical applications for both short- and long-term models. Through this guide, readers will learn how to create efficient systems that facilitate the integration of renewable energy into the grid and simultaneously manage end-users' energy consumption. The short-term operation of Home Energy Management Systems is analyzed through various lenses, including renewable energy integration, energy storage integration, uncertainty in parameters, off-grid operation, outages and events, resilience, electric vehicle integration, and battery swapping strategy. The modelling of these topics is explained with step-by-step instructions, and the parameters and implications are thoroughly discussed. Additionally, the book offers insight into the long-term expansion planning for residential microgrids, providing a detailed examination of dynamic modeling, control, and stability of these small-scale energy systems. Throughout the book, simple and advanced examples are provided, and each example comes with numerical data, detailed formulation, modelling, and simulation.

Materials for Electronics Security and Assurance reviews the properties of materials that could enable devices that are resistant to tampering and manipulation. The book discusses recent advances in materials synthesis and characterization techniques for security applications. Topics addressed include anti-reverse engineering, detection, prevention, track and trace, fingerprinting, obfuscation, and how materials could enable these security solutions. The book introduces opportunities and challenges and provides a clear direction of the requirements for material-based solutions to address electronics security challenges. It is suitable for materials scientists and engineers who seek to enable future research directions, current computer and hardware security engineers who want to enable materials selection, and as a way to inspire cross-collaboration between both communities.

Structural Health Monitoring/Management (SHM) in Aerospace Structures provides readers with the spectacular progress that has taken place over the last twenty years with respect to the area of Structural Health Monitoring (SHM) Management. The SHM field encompasses transdisciplinary areas, including smart materials, sensors and actuators, damage diagnosis and prognosis, signal and image processing algorithms, wireless intelligent sensing, data fusion, and energy harvesting. This book focuses on how SHM techniques can be applied to aircraft, mechanical and civil engineering structures with particular emphasis on composite materials. This will be a valuable reference resource for R&D managers, materials scientists, and engineers working in the aerospace sector, for researchers and system designers working in industry, and for academia and government research agencies developing new systems for the SHM of aerospace, mechanical, and civil engineering structures.

Improving and Tailoring Enzymes for Food Quality and Functionality, Second Edition covers the most relevant information demanded in the production, engineering, and application of enzymes. The title is very detailed and an important cross-discipline resource that merges academia and industry. This totally revised new edition covers a broad range of topics related to enzymes and their use in food, presenting both the fundamental theory and practical application, updated with interesting novel information on biosensors, waste, valorization, up-cycling and engineering perspectives, besides an increased focus on sustainability.

Advanced Ceramics for Photocatalytic Membranes: Synthesis Methods, Characterization and Performance Analysis, and Applications in Water and Wastewater Treatment reviews recent research on the application and use of advanced ceramic materials in photocatalytic membrane processes. Sections cover current developments in photocatalytic membrane processes, synthesis and fabrication techniques using either physical or chemical approaches, diverse characterization methods and performance evaluations, and various types of environmental applications. The book is not only limited to the conceptual theory, it also gives a detailed review of recent progress in materials science. Readers will find applications in different disciplines, i.e., chemistry, physics, and mechanics that are critically required in modern science and engineering. This across-the-board briefing on the field is suitable for use as a major reference, as well as a knowledge sharing tool.

Fractional Difference, Differential Equations, and Inclusions: Analysis and Stability is devoted to the existence and stability (Ulam-Hyers-Rassias stability and asymptotic stability) of solutions for several classes of functional fractional difference equations and inclusions. Covered equations include delay effects of finite, infinite, or state-dependent nature, and tools used to establish the existence results for the proposed problems include fixed point theorems, densifiability techniques, monotone iterative technique, notions of Ulam stability, attractivity and the measure of non-compactness, as well as the measure of weak noncompactness. The tools of fractional calculus are found to be of great utility in improving the mathematical modeling of many natural phenomena and processes occurring in the areas of engineering, social, natural, and biomedical sciences. All abstract results in the book are illustrated by examples in applied mathematics, engineering, biomedical, and other applied sciences.

A Practical Guide to Planning, Writing, and Reviewing Medical Device Clinical Evaluation Reports guides readers through clinical data evaluation of medical devices that is in compliance with the EU MDR requirements and other similar regulatory requirements throughout the world. This book brings together knowledge learned as the author constructed hundreds of CERs and taught thousands of learners on how to conduct clinical data evaluations. This book will support training for clinical engineers, clinical evaluation scientists, and experts reviewing medical device CERs, and will help individual writers, teams and companies to develop stronger, more robust CERs.

Soft Particles, Volume 62 in the Advances in Chemical Engineering series, highlights advances in the field, with this new volume covering an Introduction to soft particles: state-of-the-art and perspectives, Synthesis of microgels and nanogels via covalent cross-linking strategies, Design and modelling of sub-micron particles via innovative precipitation and self-assembly, Smart functionalization of polymers and particles: an overview of the chemical strategies, Nanomechanical properties of soft particles, Dynamics and rheology of soft particles, Degradable aqueous polymer dispersions, Food-biopolymers for nanogel fabrication, Nanoparticles, nanofibrils and tissues in cosmetic dermatology, Advanced approaches in cancer therapy via administration of polymer-based particles, and more.

Functional Microbiomes II, Volume 68in theAdvances in Ecological Researchseries, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters include Investigating the core microbiome concept: Daphnia as a case study and Soil Microbiome

Inherently Safer Design, Volume Seven in this ongoing series, highlights new advances in chemical engineering, with interesting chapters that provide an Introduction to Inherently Safer Design (ISD), ISD Fundamentals, History of ISD, ISD Life Cycle Considerations, ISD Indices, ISD and Human Factors, Conceptual and Practical Applications of ISD, Challenges to ISD Application, ISD Regulatory Requirements, ISD Case Studies, Risk-based ISD, ISD and Digitalization. ISD and Inherently Safer Operation (ISO), and the Future of ISD.

Annual Reports on NMR Spectroscopy, Volume 110, presents the latest release in a series that has established itself as a premier resource for both specialists and non-specialists interested in new techniques and applications pertaining to NMR spectroscopy.