Books published by Humana Press Inc.

The authors' cross-disciplinary approach, with expertise acquired from studying disease-causing viruses, bacteria, fungi, and protozoa, reveals how sequence information from diverse pathogens has uncovered novel targets for drug discovery, antigenic determinants for vaccine development, as well as diagnostic tools.

They also delineate the surgical management of the heart patient with discussions of postoperative management and its complications and of specific surgical procedures such as coronary artery bypass grafting, valve surgery, pacemaker and defibibrillators, and surgical management of heart failure.

There is also increased coverage of the animal models used in the study of neuroinflammatory mechanisms, of the new imaging methods that allow the noninvasive evaluation of microglial activation in human neurodegernerative disorders, and of the role of neuroinflammation in amyloid-dependent neuronal lysis.

The second edition of this volume focuses on applied bioinformatics with specific applications to crops and model plants. Plant Bioinformatics: Methods and Protocols is aimed at plant biologists who have an interest in, or requirement for, accessing and manipulating huge amounts of data being generated by high throughput technologies. This book would also be of interest to bioinformaticians and computer scientists who would benefit from an introduction to the different tools and systems available for plant research. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and software, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and thorough, Plant Bioinformatics: Methods and Protocols helps researchers with the increasing volume and diversity of data from different plants and also the integration of multiple diverse forms of data.

Stroke Essentials for Primary Care: A Practical Guide is a must-have resource, offering the essential, practical knowledge required to evaluate and treat stroke patients.

This volume details the latest technology in treating eye injuries and infections. Coverage reviews issues such as intraocular lens implants, biocompatibility of materials, retinal implants, testing models, and software designs.

The aim of Molecular Mechanisms of Neurotransmitter Release is to provide up-to-date, in-depth coverage of essentially all major mole- lar mechanisms of neurotransmitter release.

In particular, the methods can be used to identify in clinical samples those genetic mutations responsible for such congenital abnormalities as Marfan syndrome, Williams-Beuren Syndrome, Alagille syndrome, Noonan syndrome, and Friedreich ataxia.

In this second edition, the world's leading experts on prostate cancer detection update the previous edition with the latest findings. It incorporates a series of thoughtful and cutting-edge works from the world's experts in prostate cancer screening.

This book presents a comprehensive review of the inflammatory myopathies, including dermatomyositis, polymyositis, and inclusion body myositis. Representing the most up-to-date knowledge on this family of diseases, this book is the gold-standard in its field.

In medical practice there are often complex cases that make extraordinary demands on a clinician's knowledge and ingenuity. In Challenging Cases in Allergy and Immunology, the authors provide these types of fascinating, and informative cases to complement a basic knowledge of diagnosis and management in these fields.

Treatment will cover such topics as guidelines for treating posttraumatic stress disorder, PTSD and the use of mental health services, cognitive intervention therapy, and large scale clinical trials in PTSD.

A richly illustrated medical atlas of the five main human sensory systems together with their neural pathways, from primary sensation to processing by the brain. There are also easy-to-use tables providing an overview of the nerves and arteries of the eye and orbit and clinical specimens of the eye and optic pathways.

In this volume expert researchers in the field detail the many methods for further research into regulation of mitochondrial function. Chapters focus on mitochondria with other cellular components, discussing how these interactions influence the dynamics of mitochondrial structure and biogenesis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Mitochondrial Regulation: Methods and Protocols seeks to aid advanced undergraduates, graduates, postgraduates, and beginning researchers in the areas of molecular and cellular biology, biochemistry and bioenergetics.

This history of cancer patient surveillance after curative-intent treatment covers methodologies used in the past and present, the rationale behind them, likely future methodologies, the cost of surveillance, definitions of terms used in the field, and more.

Ranging from the evolution of pathogenicity to oceanic carbon cycling, the many and varied roles that bacteriophages play in microbial ecology and evolution have inspired increased interest within the scientific community. This title provides both classical and advanced molecular techniques.

Therapeutic applications within regenerative biomedicine has gained tremendous interest from a growing, multidisciplinary community of investigators in recent years, driven by the hope of finding cures for several diseases.

In Osteoporosis and Osteoarthritis expert investigators detail modern tools to enhance discovery in bone and cartilage biology and promote translational research in osteoporosis and osteoarthritis.

International experts from world-renowned medical schools comprehensively review for practicing clinicians and scientists alike the latest understanding of the epidemiology, causation, and consequences of diabetes and obesity.

Writing in an easy-to-read format-background, diagnosis, and disease management-and emphasizing practical techniques of evaluation and treatment, the authors explain the basic mechanisms underlying cardiovascular disease states and the treatment strategies that arise from them.

Updated and expanded for the second edition, this concise and thorough guide to clinical management of pediatric endocrine disorders covers growth, hypothalamic, pituitary, adrenal, thyroid, calcium and bone and reproductive disorders, and metabolic syndromes.

In Situ Hybridization Protocols, Fourth Edition contains 21 protocols that utilize the in situ hybridization technology to document or take advantage of the visualization of specific RNA molecules.

The field of adipose tissue biology has been expanding at a very rapid pace in the last few years. The volume is divided in four sections: the first two deal with basic adipose tissue and adipokine biology, while the last two address the problem of obesity and alterations in adipose tissue function from an epidemiological and clinical standpoint.

An extraordinary compendium of information on herbal medicine, Medicinal Plants of the World, Volume 2 comprehensively documents the medicinal value of twenty-four major plants species widely used around the world in medical formulations.

Plant Cell and Tissue Culture continues the high standards of Humana's Methods in Molecular Biology series. Its step-by-step approach (a hallmark of the series) is applied to a wide range of basic laboratory techniques and culture conditions appropriate to plant cells.Because of the diversity of cell types, species, and culture methods, much of this volume is devoted to the culture of particular cell types and to the regeneration of these cells into whole plants. Special attention is also given to the genetic modification of plants, as well as to the economic significance of plant products. Chapters cover a wide range of topics and techniques, including:. tissue culture media and selection . cryopreservation . callus culture techniques . organ culture . embryogenesis . batch culture . large-scale culture . hormonal control . fertilization techniques . gene transfer . cell immobilization . production systems . cell product purification . DNA expression . electrofusion of plant cells . mutant selection . mutagenesis techniques . automation . transfer of nuclei . protoplast culture . media analysis . micropropagation.A detailed appendix lists the formulas for the most commonly employed plant cell media. Comprehensive, easy to follow, and a pleasure to use, Pollard and Walker's Plant Cell and Tissue Culture is an essential tool for everyone--at all levels of proficiency and experience--involved in plant culture.

Thus, the function of the brain as a coordinator of vital homeostatic reflexes, and complex body reactions to external challenges, depends critically on the rate of oxygen delivery and oxygen consumption.