Books published by Humana Press Inc.

Combat Medicine is meant to be a concise manual for the young clinical or basic investigator who is studying organ injury following trauma or toxic or infectious assaults either in an urban or battlefield setting, with an emphasis on current research issues in emergency and military medicine.

With the introduction of cardiac surgery more than five decades ago and the use of the heart-lung machine for open heart surgical procedures granting the surgeon unlimited time in which to operate inside the heart, a complex task has been given to the Perfusionist.

A state-of-the art collection of readily reproducible laboratory methods for assessing chemosensitivity in vitro and in vivo, and for assessing the parameters that modulate chemosensitivity in individual tumors.

This updated and expanded book was written with the underlying conviction that global health and nutrition problems can only be solved through a firm understanding of the different levels of causality and the interactions between the various determinants.

Now in its second edition, Modern Hematology: Biology and Clinical Management reflects the major advances in the understanding, diagnosis, and treatment of blood disorders. In 23 chapters, all major blood diseases are covered, as well as rare diseases that are of scientific interest.

Adenovirus Methods and Protocols, Second Edition, now in two volumes, is an essential resource for adenovirus (Ad) researchers beginning in the field, and an inspirational starting point for researchers looking to branch into new areas of Ad study.

In this comprehensive and cutting-edge book, leading experts explore the parameters that define germline stem cells and the mechanisms that regulate the cell behavior in order to better isolate, characterize and maintain them.

Management options for patients with colorectal cancer have undergone d- matic changes over the past decade. Whereas at the start of 1996 only one drug, 5-Fluorouracil, was available for the treatment of this disease, a mere 10 yr later, six drugs are licensed for use in colorectal cancer, and others are in the late phases of clinical development.

Preventive Cardiology: Insights Into the Prevention and Treatment of Cardiovascular Disease, Second Edition is intended for clinical cardio- gists, internists, primary care providers, and allied health care professionals who wish to extend their knowledge and expertise in the rapidly expanding field of preventive car- ology.

International experts from world-renowned medical schools comprehensively review for practicing clinicians and scientists alike the latest understanding of the epidemiology, causation, and consequences of diabetes and obesity.

The original edition of this text, Clinical Evaluation of Medical Devices: Principles and Case Studies, provided the first overview of key pr- ciples and approaches to medical device clinical trials, illustrated with a series of detailed, real-world case studies.

Part II focuses on the litigation process itself with views from the defense and plaintiff bar, and the physician as both expert and defendant. Part III looks at malpractice litigation from the viewpoint of the practicing physician.

A panel of prominent clinician-scientists comprehensively reviews the latest developments in pediatric pain management, with special emphasis on the setting in which pain is detected and managed.

The even more colo- ful "book of life" metaphor gave the promise that reading that book would lead to a veritable outpouring of new cures for diseases, hundreds of new drug targets, and a brave new world of medicine.

Additional chapters address taphonomic changes in human bodies during the early postmortem interval, arrhythmogenic ventricular dysplaisia that produces sudden death in young people, the postmortem diagnosis of death in anaphylaxis, and iatrogenici deaths.

Staying with the idea of isotopic labeling, Chapter 3 describes methods for perdeuteration and site-specific protonation and is the first of several chapters in the book that is relevant to studies of higher molecular weight systems.

Leading forensic pathologists from around the world synthesize the practical advances in a variety of important subspecialties of forensic pathology and demonstrate how the latest medical and scientific progress is being applied to solve current problems of high interest to forensic pathologists today.

Superbly illustrated with both clinical and histopathologic photographs, the book moves from a proposed new system of classification and nomenclature for vascular neoplasms, to a full discussion of benign and malignant proliferations, including hamartomas, benign neoplasms, malignant neoplasms, and several related newly reported diseases.

Cell Cycle in the Central Nervous System overviews the changes in cell cycles as they relate to tumor formation and development, while discussing how changes in the cell cycle can affect development resulting in later complications in life.

In the process of establishing the cause and manner of death, representatives of various investigative bodies have several responsibilities, including explaining the death to family members, attempting to reduce the risk of similar deaths in the future, and, if applicable, apprehending the individuals who are responsible for the death.

Leading experts in the use of MRI explain its basic principles and demonstrate its power to understand biological processes with numerous cutting-edge applications.

This challenge is particularly difficult to meet in osteoporosis, not only because has been so much new knowledge generated in recent years, but also because this there disorder has not caught the attention of many practicing physicians.

This volume reviews different regimens of hormone replacement therapy.

Among the protocol highlights are a novel two-step process that yields a high purity, less costly, DNA, the synthesis of phosphorothioates using new sulfur transfer agents, the synthesis of LNA, peptide conjugation methods to improve cellular delivery and cell-specific targeting, and triple helix formation.

In keeping with the organization used effectively in other volumes in this series, each chapter has a brief introduction followed by a list of required items, protocols, and notes designed to help the reader perform the expe- ments without difficulty.

Leading basic researchers and clinical scientists describe in detail a wide variety of established and cutting-edge techniques they have developed to study the lifecycle and biological properties of the human papillomavirus.

This work covers the applications of lectins in medical research by presenting overviews of their current use as well as detailed protocols and techniques for use by medical researchers utilizing lectins.

Highlighting recent advances in our understanding of breast cancer, this book is intended for a wide audience as a reference book.

A cutting-edge collection of readily reproducible in vitro and in vivo methods to elucidate the mechanisms associated with cannabinoid function in health and disease.

A cutting-edge review of the major research areas of adjuvant discovery, design, development, and use. The authors lay down a rational basis for vaccine adjuvant function and analyze a number of significantly distinct adjuvant-active molecules to illuminate the principles of their function and use.