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Research in genomics and pharmacogenomics is increasingly highlighting the need to move towards stratified disease descriptions and individualized treatment plans. This book explains how a confluence of biological, technological and methodological developments is making it possible to provide personalized diagnoses and treatments.
Starting with the ideas of ancient civilizations that air, earth, fire and water were the basic ingredients of all matter, this title traces the development of the science of chemistry beginning within the ranks of the alchemists.
In terms of structural complexity, the natural world presents innumerable examples of stunning beauty and high functionality, usually with the minimum of material and energy expenditure. This book covers simple molecules such as cellulose and chitin, to large biological constructs such as bacterial proteins, viruses and pollen.
The beta-beam concept for the generation of electron neutrino beams was first proposed by Piero Zucchelli in 2002. This book presents a monograph on the beta-beam concept. It describes both technical aspects and experimental aspects of the beta-beam.
Ever wondered if your patient's new symptoms are a manifestation of metastatic disease, treatment effects or are altogether unrelated to the cancer diagnosis; or whether herbal remedies interact with cancer treatment? This book answers these and many other questions, spanning from cancer prevention to palliative care.
Many biological systems and objects are intrinsically fuzzy as their properties and behaviors contain randomness or uncertainty. This book addresses several important bioinformatics topics using fuzzy concepts and approaches, including measurement of ontological similarity, protein structure prediction/analysis, and microarray data analysis.
Contains biographical information of Sir James Lighthill and his major scientific contributions to the different areas of fluid mechanics, applied mathematics, aerodynamics, linear and nonlinear waves in fluids, geophysical fluid dynamics, biofluiddynamics, and aeroelasticity. This book also includes a list of Lighthill's significant papers.
The Tao of Innovation represents the synthesis of the most influential thinking on innovation, based on nearly 30 years of real-world corporate, entrepreneurial, and consulting experience, and more than 10 years of teaching innovation and entrepreneurship to thousands of students from all walks of life and countries.
Introduces the concept of intrusion detection, discusses various approaches for intrusion detection systems (IDS), and presents the architecture and implementation of IDS. This title also includes the performance comparison of various IDS via simulation.
Presents a modern view of the different aspects of physical chemistry. With only the essential examples and steps in derivations given, this title intends to provide students/readers with the big picture first, which they need to keep in mind as they subsequently develop more detailed skills. It also includes a CD-ROM.
Offers an introduction to the fundamental concepts of computational fluid dynamics (CFD). This book presents the ABC's or bare essentials of CFD in their simplest and most transparent form.
Offers an overview of approaches to internationalization experienced by smaller manufacturing enterprises. This book focuses on the individual aspects of internationalization. It presents about 10 research cases which are supplemented with a minimum of two cases each from Denmark, Sweden, and the Czech Republic.
Serves as a historical research monograph on the biographical sketch and career of Leonhard Euler and his major contributions to numerous areas in the mathematical and physical sciences. This title contains fourteen chapters describing Euler's works on number theory, algebra, geometry, trigonometry, and differential and integral calculus.
This book presents the hotly debated question of whether quantum mechanics plays a non-trivial role in biology. In a timely way, it sets out a distinct quantum biology agenda. The burgeoning fields of nanotechnology, biotechnology, quantum technology, and quantum information processing are now strongly converging. The acronym BINS, for Bio-Info-Nano-Systems, has been coined to describe the synergetic interface of these several disciplines. The living cell is an information replicating and processing system that is replete with naturally-evolved nanomachines, which at some level require a quantum mechanical description. As quantum engineering and nanotechnology meet, increasing use will be made of biological structures, or hybrids of biological and fabricated systems, for producing novel devices for information storage and processing and other tasks. An understanding of these systems at a quantum mechanical level will be indispensable.
Covers the understanding of the role of activation-induced cytidine deaminase (AID) in the generation of antibody response to antigenic challenge.
Focuses on what is generally taught in the first two years of an undergraduate university chemistry program. This textbook contains topics in electronic structure of atoms and molecules, biochemistry, chemical reactions, energy production and even modern topics such as quantum chemistry and molecular orbital theory.
Offers an introduction to a wide body of knowledge on nonlinear dynamics and chaos. This book emphasises the understanding of basic concepts and the nontrivial character of nonlinear response, contrasting it with the intuitively simple linear response. It explains the theoretical framework using pedagogical examples from fluid dynamics.
Diffusion, or the widespread adoption of innovations, is a critical yet under-researched topic. This book adopts a multi-disciplinary and managerial process approach to understanding and promoting the adoption of innovations, based on the research and practice. It is of interest to graduates and researchers in marketing and innovation courses.
What exactly is human ageing? Can it be slowed down? These questions have puzzled scientists and laymen alike for generations, and continue to do so. This title addresses these issues by challenging pre-conceived notions of age-perception, age-acceptance and inter-age relations.
A guide to the implementation of intelligent business strategies. An intelligent business strategy is offered based on the experiences of seven market leaders in the Netherlands, combined with modern insights from organizational theory. It devotes much attention to the tools available.
This work shows how the analytical properties in the complex energy plane of the Green's functions of many particle systems account for the physical effects (level shifts, damping, instabilities) characteristic of interacting systems.
Presents an introduction to the surprising nature of change and explains how the Law of Unintended Consequences arises from the waves of change following one simple change. This book is suitable for professionals in system building or business change management, and to students studying systems in a variety of fields.
Presents an introduction to classical fluid dynamics. This book includes estimation theory, both classical and quantum, using information geometry.
Addresses significant problems in physical biology and adjacent disciplines. This volume provides a perspective on the methods and concepts at the heart of chemical and biological behavior, covering the topics of visualization; theory and computation for complexity; and macromolecular function, protein folding, and protein misfolding.
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