Books published by Mdpi AG

The goal of this Special Issue is to bring together state-of-the art articles on applied linguistics which reflect investigation carried out by researchers from different parts of the world. By bringing together papers from different perspectives, we hope to be able to gain a better understanding of the field. Hence, this Special Issue intends to address the study of language in its different dimensions and within the framework of multiple methodologies and formal accounts as used by researchers in the field. This Special Issue is dedicated to research in any area related to applied linguistics, including language acquisition and language learning; language teaching and curriculum design; language for specific purposes; psychology of language, child language and psycholinguistics; sociolinguistics; pragmatics; discourse analysis; corpus linguistics, computational linguistics and language engineering; lexicology and lexicography; and translation and interpretation.

Organophosphorus chemistry is an important discipline within organic chemistry. Phosphorus compounds, such as phosphines, trialkyl phosphites, phosphine oxides (chalcogenides), phosphonates, phosphinates and >P(O)H species, etc., may be important starting materials or intermediates in syntheses. Let us mention the Wittig reaction and the related transformations, the Arbuzov- and the Pudovik reactions, the Kabachnik–Fields condensation, the Hirao reaction, the Mitsunobu reaction, etc. Other reactions, e.g., homogeneous catalytic transformations or C-C coupling reactions involve P-ligands in transition metal (Pt, Pd, etc.) complex catalysts. The synthesis of chiral organophosphorus compounds means a continuous challenge. Methods have been elaborated for the resolution of tertiary phosphine oxides and for stereoselective organophosphorus transformations. P-heterocyclic compounds, including aromatic and bridged derivatives, P-functionalized macrocycles, dendrimers and low coordinated P-fragments, are also of interest. An important segment of organophosphorus chemistry is the pool of biologically-active compounds that are searched and used as drugs, or as plant-protecting agents. The natural analogue of P-compounds may also be mentioned. Many new phosphine oxides, phosphinates, phosphonates and phosphoric esters have been described, which may find application on a broad scale. Phase transfer catalysis, ionic liquids and detergents also have connections to phosphorus chemistry. Green chemical aspects of organophosphorus chemistry (e.g., microwave-assisted syntheses, solvent-free accomplishments, optimizations, and atom-efficient syntheses) represent a dynamically developing field. Last, but not least, theoretical approaches and computational chemistry are also a strong sub-discipline within organophosphorus chemistry.

The present book covers all research areas related to magnetic nanoparticles, magnetic nanorods, and other magnetic nanospecies, their preparation, characterization, and various applications, specifically emphasizing biomedical applications. The chapters written by the leading experts cover different subareas of the science and technology related to various magnetic nanospecies—providing broad coverage of this multifaceted area and its applications. The different topics addressed in this book will be of great interest to the interdisciplinary community active in the area of nanoscience and nanotechnology. It is hoped that this collection and its various chapters will be important and beneficial for researchers and students working in various areas related to bionanotechnology, materials science, biosensor applications, medicine, and many others. Furthermore, this book is aimed at attracting young scientists and introducing them to this field, in addition to providing newcomers with an enormous collection of literature references.

The worldwide potential of electric power generation from marine tidal currents, waves, or offshore winds is enormous. The high load factor resulting from the fluid properties and the predictable resource characteristics make tidal and wave energy resources attractive and advantageous for power generation and advantageous when compared to other renewable energies. The technologies are just beginning to reach technical and economic viability to make them potential commercial power sources in the near future. While only a few small projects currently exist, the technology is advancing rapidly and has huge potential for generating bulk power. Moreover, international treaties related to climate control and dwindling fossil fuel resources have encouraged us to harness energy sustainably from such marine renewable sources. Several demonstrative projects have been scheduled to capture tidal and wave energies. A number of these projects have now reached a relatively mature stage and are close to completion. However, very little is known to the academic world about these technologies beyond the basics of their energy conversion principles. While research emphasis is more towards hydrodynamics and turbine design, very limited activities are witnessed in power conversion interface, control, and power quality aspects. Regarding this emerging and promising area of research, this book aims to present recent results, serving to promote successful marine renewable energies integration to the grid or to standalone microgrids.

In Noether's original presentation of her celebrated theorem of 1918, allowances were made for the dependence of the coefficient functions of the differential operator which generated the infinitesimal transformation of the Action Integral upon the derivatives of the dependent variable(s), the so-called generalized, or dynamical, symmetries. A similar allowance is to be found in the variables of the boundary function, often termed a gauge function by those who have not read the original paper. This generality was lost after texts such as those of Courant and Hilbert or Lovelock and Rund confined attention to only point transformations. In recent decades, this diminution of the power of Noether's Theorem has been partly countered, in particular, in the review of Sarlet and Cantrijn. In this Special Issue, we emphasize the generality of Noether's Theorem in its original form and explore the applicability of even more general coefficient functions by allowing for nonlocal terms. We also look at the application of these more general symmetries to problems in which parameters or parametric functions have a more general dependence upon the independent variables.

Some of the most beautiful studies in Mathematics are related to Symmetry and Geometry. For this reason, we select here some contributions about such aspects and Discrete Geometry. As we know, Symmetry in a system means invariance of its elements under conditions of transformations. When we consider network structures, symmetry means invariance of adjacency of nodes under the permutations of node set. The graph isomorphism is an equivalence relation on the set of graphs. Therefore, it partitions the class of all graphs into equivalence classes. The underlying idea of isomorphism is that some objects have the same structure if we omit the individual character of their components. A set of graphs isomorphic to each other is denominated as an isomorphism class of graphs. The automorphism of a graph will be an isomorphism from G onto itself. The family of all automorphisms of a graph G is a permutation group.

DNA methylation, a modification found in most species, regulates chromatin functions in conjunction with other epigenome modifications, such as histone post-translational modifications and non-coding RNAs. In mammals, DNA methylation has an essential role in development by orchestrating the generation and maintenance of the phenotypic diversity of human cell types. Recent years have brought spectacular advances in our understanding of the mechanism, function and regulation of DNA methyltransferases through their interaction with other epigenome modifications, chromatin factors and post-translational modifications, which are described in this Special Issue of Genes. Manuscripts are specifically addressing describing the targeting and regulation of DNA methyltransferases by interacting factors and their roles in cellular differentiation and the development of diseases. Prof. Dr. Albert Jeltsch and Prof. Dr. Humaira Gowher, Guest Editors

We are currently experiencing a climate crisis that is associated with extreme weather events worldwide. Some of its most noticeable effects are increases in temperatures, droughts, and desertification. These effects are already making whole regions unsuitable for agriculture. Therefore, we urgently need global measures to mitigate the effects of climate breakdown as well as crop alternatives that are more stress-resilient. These crop alternatives can come from breeding new varieties of well-established crops, such as wheat and barley. They can also come from promoting underutilized crop species that are naturally tolerant to some stresses, such as quinoa. Either way, we need to gather more knowledge on how plants respond to stresses related to climate breakdown, such as heat, water-deficit, flooding high salinity, nitrogen, and heavy metal stress. This Special Issue provides a timely collection of recent advances in the understanding of plant responses to these stresses. This information will definitely be useful to the design of new strategies to prevent the loss of more cultivable land and to reclaim the land that has already been declared unsuitable.

Imaging and analysis are widely involved in various research fields, including biomedical applications, medical imaging and diagnosis, computer vision, autonomous driving, and robot controls. Imaging and analysis are now facing big changes regarding intelligence, due to the breakthroughs of artificial intelligence techniques, including deep learning. Many difficulties in image generation, reconstruction, de-noising skills, artifact removal, segmentation, detection, and control tasks are being overcome with the help of advanced artificial intelligence approaches. This Special Issue focuses on the latest developments of learning-based intelligent imaging techniques and subsequent analyses, which include photographic imaging, medical imaging, detection, segmentation, medical diagnosis, computer vision, and vision-based robot control. These latest technological developments will be shared through this Special Issue for the various researchers who are involved with imaging itself, or are using image data and analysis for their own specific purposes.

For the editors of this collection, new materialisms have always been the entanglement of epistemology, ontology, ethics, and politics. Looking back to the notion of “situated knowledges” (Haraway, 1988) that – among others – “planted the seed for feminist new materialism” (van der Tuin, 2015, 26) – one sees how those (at least) four planes are entangled (Rogowska-Stangret, 2018) in order to bring forth “response-able” (Haraway, 2008) research. New materialism is thus an ethico-onto-epistemological framework (Barad, 2007; Revelles-Benavente, 2018) that by activating its ethico-politics helps to diagnose, infer, and transform gendered, environmental, anthropocentric, social injustices from a multidimensional angle. Social injustices are a driving motivation to pursue research and are the reason why the editors and authors of this Special Issue cannot understand new materialism without feminism (in the lines of eds. Hinton & Teusch, 2015). Contemporary feminist researchers are providing new materialisms with a transversal approach, (Yuval-Davis 1997) that comes from many different disciplines without canonizing back again knowledge creation and production and in hope that they will not enter back into classifixations (van der Tuin, 2015). It is “situated” (Haraway, 1988) research “response-able” (Haraway, 2008) to material-discursive practices that iterate in a dynamic conceptualization of matter.

Mobile robotics is a challenging field with great potential. It covers disciplines including electrical engineering, mechanical engineering, computer science, cognitive science, and social science. It is essential to the design of automated robots, in combination with artificial intelligence, vision, and sensor technologies. Mobile robots are widely used for surveillance, guidance, transportation and entertainment tasks, as well as medical applications. This Special Issue intends to concentrate on recent developments concerning mobile robots and the research surrounding them to enhance studies on the fundamental problems observed in the robots. Various multidisciplinary approaches and integrative contributions including navigation, learning and adaptation, networked system, biologically inspired robots and cognitive methods are welcome contributions to this Special Issue, both from a research and an application perspective.

Mobile robotics is a challenging field with great potential. It covers disciplines including electrical engineering, mechanical engineering, computer science, cognitive science, and social science. It is essential to the design of automated robots, in combination with artificial intelligence, vision, and sensor technologies. Mobile robots are widely used for surveillance, guidance, transportation and entertainment tasks, as well as medical applications. This Special Issue intends to concentrate on recent developments concerning mobile robots and the research surrounding them to enhance studies on the fundamental problems observed in the robots. Various multidisciplinary approaches and integrative contributions including navigation, learning and adaptation, networked system, biologically inspired robots and cognitive methods are welcome contributions to this Special Issue, both from a research and an application perspective.

Mobile robotics is a challenging field with great potential. It covers disciplines including electrical engineering, mechanical engineering, computer science, cognitive science, and social science. It is essential to the design of automated robots, in combination with artificial intelligence, vision, and sensor technologies. Mobile robots are widely used for surveillance, guidance, transportation and entertainment tasks, as well as medical applications. This Special Issue intends to concentrate on recent developments concerning mobile robots and the research surrounding them to enhance studies on the fundamental problems observed in the robots. Various multidisciplinary approaches and integrative contributions including navigation, learning and adaptation, networked system, biologically inspired robots and cognitive methods are welcome contributions to this Special Issue, both from a research and an application perspective.

This Special Issue focuses mainly on techniques and the relative formalism typical of numerical methods and therefore of numerical analysis, more generally. These fields of study of mathematics represent an important field of investigation both in the field of applied mathematics and even more exquisitely in the pure research of the theory of approximation and the study of polynomial relations as well as in the analysis of the solutions of the differential equations both ordinary and partial derivatives. Therefore, a substantial part of research on the topic of numerical analysis cannot exclude the fundamental role played by approximation theory and some of the tools used to develop this research. In this Special Issue, we want to draw attention to the mathematical methods used in numerical analysis, such as special functions, orthogonal polynomials, and their theoretical tools, such as Lie algebra, to study the concepts and properties of some special and advanced methods, which are useful in the description of solutions of linear and nonlinear differential equations. A further field of investigation is dedicated to the theory and related properties of fractional calculus with its adequate application to numerical methods.

The development of a closed-loop cycle is a necessary condition so as to develop a circular economy model as an alternative to the linear model, in order to maintain the value of products and materials for as long as possible. For this motive, the definition of the value must be demonstrated for both the environment and the economy. The presence of these analyses should be associated with the social dimension and the human component. A strong cooperation between social and technical profiles is a new challenge for all researchers. End of life of products attract a lot of attention, and the final output could be the production of technologies suitable for managing this waste.

Supply chains are currently globalized and companies operate internationally owing to the fact that raw materials, production processes, and the consumption of the final products are carried out in different countries. This implies high material and information flow, which incurs high costs associated with the supply chain and logistics, sometimes up to 60% of the total cost of the product. Therefore, companies seek to optimize their resources to reduce these costs and improve sustainability in a globalized market. This book, entitled Tools, Methodologies and Techniques Applied to Sustainable Supply Chains, contains 15 chapters that report case studies applied to industrial and service sectors. The authors come from areas such as Mexico, Colombia, Italy, Sweden, Slovakia, China, and Australia. They indicate how managers make use of tools and techniques to solve problems associated with supply chains to reduce their cost and remain competitive. A great effort has been made to analyze this problem, and the methodologies are clearly described here to facilitate the reproducibility of each technique and tool. This was done in the hope that hoping that they may one day be applied in more companies.

Dietary trace minerals are pivotal and hold a key role in numerous metabolic processes. Trace mineral deficiencies (except for iodine, iron, and zinc) do not often develop spontaneously in adults on ordinary diets; infants are more vulnerable because their growth is rapid and their intake varies. Trace mineral imbalances can result from hereditary disorders (e.g., hemochromatosis, Wilson disease), kidney dialysis, parenteral nutrition, restrictive diets prescribed for people with inborn errors of metabolism, or various popular diet plans. The Special Issue “Dietary Trace Minerals” comprised 13 peer-reviewed papers on the most recent evidence regarding the dietary intake of trace minerals, as well as their effect on the prevention and treatment of non-communicable diseases. Original contributions and literature reviews further demonstrated the crucial and central part that dietary trace minerals play in human health and development. This editorial provides a brief and concise overview of the content of the Dietary Trace Minerals Special Issue.

Seaweeds are recognized as highly nutritious, and their use in gastronomy is increasing. Their health benefits and their potential to prevent several diseases have also been established. In this Special Issue several health effects are discussed, with more emphasis on their antitumor activity and potential use to treat Alzheimer’s disease. The key bioactive metabolites, from which phlorotannins can be highlighted, are presented, as well as some important in vivo studies. Altogether, the chapters provide in-depth information about the biological activities of seaweed metabolites, contributing to elucidate the health effects of seaweed.

Non-Newtonian (non-linear) fluids are common in nature, for example, in mud and honey, but also in many chemical, biological, food, pharmaceutical, and personal care processing industries. This Special Issue of Fluids is dedicated to the recent advances in the mathematical and physical modeling of non-linear fluids with industrial applications, especially those concerned with CFD studies. These fluids include traditional non-Newtonian fluid models, electro- or magneto-rheological fluids, granular materials, slurries, drilling fluids, polymers, blood and other biofluids, mixtures of fluids and particles, etc.

The cytoplasm of Gram-negative bacteria is bound by three layers: an inner membrane, a layer of peptidoglycan, and an outer membrane. The outer membrane is an asymmetric lipidic bilayer, with phospholipids on its inner surface and lipopolysaccharides (LPSs) on the outside, with the latter being the major component of the outer leaflet and covering nearly three-quarters of the total outer cell surface. All LPSs possess the same general chemical architecture independently of bacterial activity (pathogenic, symbiotic, commensal), ecological niche (human, animal, soil, plant, water), or growth conditions. Endotoxins are large amphiphilic molecules consisting of a hydrophilic polysaccharide component and a covalently bound hydrophobic and highly conserved lipid component, termed lipid A (the endotoxin subunit). The polysaccharide component can be divided into two subdomains: the internal and conserved core region as well as the more external and highly variable O-specific chain, also referred to as the O-antigen due to its immunogenic properties. LPSs are endotoxins, one of the most potent class of activators of the mammalian immune system; they can be released from cell surfaces of bacteria during multiplication, lysis, and death. LPS can act through its biological center (lipid A component) on various cell types, of which macrophages and monocytes are the most important.

Widening International Entrepreneurship Research addresses several unresolved questions and thus moves forward by acknowledging that future international entrepreneurship research needs to find new ways to further enrich its knowledge. The book presents the results of six studies that explain how human resource management contributes to the strategy of early internationalization, compares different experiences in several countries, assesses innovation in international entrepreneurship education teaching, analyses the effects of entrepreneurial education on entrepreneurial skills, and provides new knowledge about the effect of digitalization on firm performance in international markets. This collection of papers reviews the main factors that have been identified as having a high explanatory power at different levels.

Nowadays, the sustainable built environment planning in most cities has come to a turning point as the growth in traffic and population has become a serious concern and put tremendous pressure on both the environment and people in these cities. It is therefore important to find new ways or lifestyles—such as compact city, transit-oriented development (TOD) formulations—that are more flexible, inclusive, and sustainable. Furthermore, for the sustainable built environment and urban growth management, not only should the growth management principles—which include smart growth, sustainable growth, and inclusive growth—be taken into account but innovative/smart planning strategies—such as mixed use design, green transport, and new urbanism—are also utilized in planning sustainable built environments in order to prevent the urban sprawl development that has occurred.

Industrial process tomography (IPT) is becoming an important tool for Industry 4.0. It consists of multidimensional sensor technologies and methods that aim to provide unparalleled internal information on industrial processes used in many sectors. This book showcases a selection of papers at the forefront of the latest developments in such technologies.

Virus bioinformatics is evolving and succeeding as an area of research in its own right, representing the interface of virology and computer science. Bioinformatic approaches to investigate viral infections and outbreaks have become central to virology research, and have been successfully used to detect, control, and treat infections of humans and animals. As part of the Third Annual Meeting of the European Virus Bioinformatics Center (EVBC), we have published this Special Issue on Virus Bioinformatics.