Books published by Morgan & Claypool Publishers

This book focuses on skin photoaging, the premature aging of skin due to environmental effects such as exposure to UV (UVA, UVB) radiation from the sun. Slowing the aging process and rejuvenation have been one of the major goals of medicine and are in high

Epithelial cells exhibit an apical-basolateral axis of polarity that is generated during embryogenesis, is maintained throughout adult life in the face of constant cell regeneration, and is perturbed in several epithelial-associated diseases. Ths book examines the structural and functional organization of epithelial tissues, as well as the events critical for generating epithelial asymmetry.

Peripheral arterial disease (PAD) is a cardiovascular disorder of the peripheral vasculature due to progressive atherosclerotic stenosis of conduit arteries restricting blood flow to tissues. PAD is typically a disease of older individuals. This title discusses PAD signs and symptoms, pathophysiological mechanisms, current management, and future disease targets and possible therapeutic treatments.

Reviews the cellular mechanisms contributing to astrocyte-mediated vasodilation and vasoconstriction of parenchymal arterioles. Primarily, the authors discuss how activity-dependent changes in astrocytic Ca2+ contribute to the release of vasoactive signals involved in neurovascular coupling.

Focuses on the fully classical theory of FELs with application to FEL oscillators, and develops the fundamentals of FEL theory in sufficient depth to provide both a solid understanding of FEL physics and a solid background for research in the field. All numerical approximations were developed by the author and numerous examples are included throughout.

Offers an examination of classical mechanics. Usually "classical" calls to mind Newtonian mechanics and that is indeed where modern physics started. The bulk of the book is devoted to sections which will contain mainly categorized groups of Q&As from the web site www.AskThePhysicist.com, sort of a "Best of Ask the Physicist".

Illustrates the depth and diversity of writers, thinkers, and makers who have been inspired by Ada Lovelace, the English mathematician and writer. The volume, which commemorates the bicentennial of Ada's birth in December 1815, celebrates Lovelace's many achievements as well as the impact of her life and work, which has reverberated widely since the late nineteenth century.

Myocardial perfusion is collectively regulated by a complex variety of mechanisms. This book considers each of these determinants with particular emphasis on the functional interaction between the physical and biological determinants of myocardial perfusion. Pathophysiologic aspects of coronary atherosclerosis and cardiovascular disease states are also considered.

Instead of viewing interference as an inherently counterproductive phenomenon that should to be avoided, this title examines how to design practical systems that transform interference into a harmless, and even a beneficial phenomenon. To achieve this goal, the book considers how wireless signals interact when they interfere, and use this understanding in our system designs.

This book is designed to help the non-specialist user of spectroscopic measurements and electronic structure computations to achieve a basic understanding of the underlying concepts of quantum chemistry. It can be used to teach introductory quantum chemistry to second-or third-year undergraduates.

Dengue is a major public health concern throughout the tropical and sub-tropical regions of the world. This book focuses on understanding host-pathogen interactions. It presents readers with a comprehensive description of the immune response to the Dengue virus, detailing how DENV unbalances host homeostasis.

The understanding of the pathophysiology of erectile dysfunction (ED) has advanced significantly over the past two decades. This book provides an in-depth analysis of the current knowledge of the pathophysiology of ED in order to provide the reader with an up-to-date and comprehensive understanding of the pathophysiology of ED.

Quantum theory is one of the most successful of all physical theories. Our everyday world is dominated by devices that function because of knowledge of the quantum world. Yet many, physicists and non-physicists alike, find the theory which explains the beh

This book describes the advanced stability theories for magnetically confined fusion plasmas, especially in tokamaks. As the fusion plasma sciences advance, the gap between the textbooks and cutting-edge researches gradually develops. This book fills in

Summarises both current clinical management of motor neuron disease (MND) and our present understanding of the molecular pathogenesis of MND. Study of C9ORF72-MND has the potential to rapidly advance both of these aspects in the coming years.

Takes the reader on an incredible journey to explore the exciting discoveries in genetics and molecular biology. The reader will embark on a genetic odyssey starting with the "Father of Genetics", Gregor Mendel, leading on to the story of photo 51 and the discovery of the structure of the DNA double helix, and culminating with the invention of the polymerase chain reaction.

Provides an overview of angiogenesis processes and discusses the importance of VEGF-C and VEGF-D precursors processing by the proprotein convertases during the activation of VEGFR-2 and VEGFR-3 receptors and the mediation of their functions during angiogenesis, lymphangiogenesis, and tumorigenesis.

Necrotizing enterocolitis is an acute inflammatory necrosis of bowel that primarily afflicts premature infants in the neonatal intensive care unit setting. Although patients who develop this disease have high morbidity and mortality rates, the pathogenesis is poorly understood. This title discusses new approaches based on sound evidence.

Describes the general structure of G protein-coupled receptors, including the information obtained from crystal structure determination that has given an insight into the activation mechanism of these receptors. In addition, the book summarizes the components of the signal transduction system (including G proteins, effectors and second messengers generally activated by the neuropeptide receptors).