Books published by Springer Basel

This book draws on an eight-year study carried out in the DOCG Prosecco area of Italy, a wine region known worldwide. It is unique in the sense that it is based on one of the most comprehensive investigations into terroir zoning ever performed in Italy.By drawing attention to the complex interrelations between environmental and human factors that influence the growth and production of the Glera grape, the study illustrates the distinct correlation between a wine and its 'terroir'.It shows that the morphology of the sites, the meso and microclimate, the soil, the grapevine planting density, the trellising system, the yield of the vineyard, and the vine water status in the summer lead to unique combinations of grape maturity, acidity, and aroma that ultimately influence the sensory properties of the wines produced. Furthermore, the book details numerous technical and agronomic considerations, specific to the "e;Glera"e; grape variety, for different production strategies, including a section on the impact of climate change on cv "e;Glera"e; phenology."e;The Power of the Terroir: the Case Study of Prosecco Wine"e; represents a valuable resource for anyone involved in studies or research activities in the fields of viticulture, climatology, agronomic sciences or soil sciences, but is also of interest to vine growers, professionals in the wine industry, and wine enthusiasts in general.

Highlighting 15 selected chiral structures, which represent candidate or marketed drugs, and their chemical syntheses, the authors acquaint the reader with the fascinating achievements of synthetic and medicinal chemistry.The book starts with an introduction treating the discovery and development of a new drug entity. Each of the 15 subsequent chapters presents one of the target structures and begins with a description of its biological profile as well as any known molecular mechanisms of action, underlining the importance of its structural and stereochemical features. This section is followed by detailed discussions of synthetic approaches to the chiral target structure, highlighting creative ideas, the scaling-up of laboratory methods and their replacement by efficient modern technologies for large-scale production. Nearly 60 synthetic reactions, most of them stereoselective, catalytic or biocatalytic, as well as chiral separating methodologies are included in the book.Vitomir Sunjic and Michael J. Parnham provide an invaluable source of information for scientists in academia and the pharmaceutical industry who are actively engaged in the interdisciplinary development of new drugs, as well as for advanced students in chemistry and related fields.

This text is based on lectures Couturat gave at the University Caen. It is an outstanding document of the popularization and propagation of symbolic logic around 1900, and it is the only manuscript mentioned in his correspondence that has been rediscovered.

The book deals with continuous piecewise linear differential systems in the plane with three pieces separated by a pair of parallel straight lines. Moreover, these differential systems are symmetric with respect to the origin of coordinates. This class of systems driven by concrete applications is of interest in engineering, in particular in control theory and the design of electric circuits. By studying these particular differential systems we will introduce the basic tools of the qualitative theory of ordinary differential equations, which allow us to describe the global dynamics of these systems including the infinity. The behavior of their solutions, their parametric stability or instability and their bifurcations are described. The book is very appropriate for a first course in the qualitative theory of differential equations or dynamical systems, mainly for engineers, mathematicians, and physicists.