Books published by Springer International Publishing

This book reviews math topics relevant to non-mathematics students and scientists, but which they may not have seen or studied for a while. These math issues can range from reading mathematical symbols, to using complex numbers, dealing with equations involved in calculating medication equivalents, the General Linear Model (GLM) used in e.g. neuroimaging analysis, finding the minimum of a function, independent component analysis, or filtering approaches. Almost every student or scientist, will at some point run into mathematical formulas or ideas in scientific papers that may be hard to understand, given that formal math education may be some years ago. In this book we will explain the theory behind many of these mathematical ideas and expressions and provide readers with the tools to better understand them. We will revisit high school mathematics and extend and relate this to the mathematics you need to understand the math you may encounter in the course of your research. This book will help you understand the math and formulas in the scientific papers you read. To achieve this goal, each chapter mixes theory with practical pen-and-paper exercises such that you (re)gain experience with solving math problems yourself. Mnemonics will be taught whenever possible. To clarify the math and help readers apply it, each chapter provides real-world and scientific examples.In this new edition, two new chapters covering statistics and differential equations have been added, which have been workshopped in the 'authors' popular lecture series in order to maximize the benefit for readers.

Despite its complexity, innovation is often depicted within academic literature as a phenomenon that is innately good and always necessary. This thought-provoking volume presents a more nuanced view ¿ through a number of paired chapters for and against, as well as more general critiques of innovation and several suggested new lines of inquiry, the book will be of interest to all with a broader interest in innovation.

This second edition provides new and updated methods for establishing reliable and reproducible experimental models of cardiovascular diseases. Chapters detail practical protocols from expert laboratories focusing on cardiovascular research, that would be critical in exploring novel discoveries in cardiac biology, and the development of effective therapeutic approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Experimental Models of Cardiovascular Diseases: Methods and Protocols, Second Edition aims to provide detailed and practical protocols that will be valuable tools for researchers in cardiology to conduct their research.

This fully updated volume explores N-Methyl-D-aspartate receptors (NMDARs), and the structure-function relations, principles, and rules that govern how NMDARs operate in brain processing under normal and pathological conditions. With chapters from leading laboratories around the world, this book examines the expression and purification of diverse NMDA receptor subtypes, gene targeting and generation of conditional NMDAR mutant mouse lines, studies of NMDARs in zebrafish, electrophysiological studies, NMDARs modeling in silico, drug development with artificial intelligence, and much more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, NMDA Receptors: Methods and Protocols, SecondEdition serves as an ideal guide to the diversity of possible approaches in the field of NMDARs and the progress that has been made in recent years.

This volume explores recent innovations across the entire pipeline of imaging signal transduction, cell preparation, cellular manipulation, image acquisition, and computational analysis. The chapters in this book cover topics such as rapid preparation of living Drosophila pupal macrophages for ex vivo imaging; controlling the potency of T cell activation using an optically tuneable chimeric antigen receptor; in situ imaging of proteins using DNA-PAINT super-resolution microscopy; reconstructing signaling networks using biosensor barcoding; and morphological, spatial, and dynamic models for cellular components. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and authoritative, Imaging Cell Signaling is a valuable resource that provides guidance to researchers looking to learn how to effectively tailor design projects to image, manipulate, and model signal transduction.

This second edition provides new and updated chapters covering computational and mathematical techniques and concepts related to the field of comparative genomics. The topics covered in the chapters range from those that address general techniques and concepts that apply to all organisms to others that are specialized and apply to specific biological systems such as viruses, bacteria, nematodes, and insects. Well-known comparative genomics web-based platforms are also covered in specific chapters. Written in the highly successful Methods in Molecular Biology series format, many chapters include introductions to their respective topics and step-by-step comparison procedures, demonstrated on actual sets of genome sequences.Authoritative and cutting-edge, Comparative Genomics: Methods and Protocols, Second Edition aims to ensure successful results in the further study of this vital field.

This book offers an innovative conceptual and methodological approach to one of the most significant health and wellbeing challenges for contemporary youth: body image. The social and cultural dimensions shaping body ideals and young people¿s body image concerns have not been adequately explored in the current landscape of social media and youth body cultures. The author provides a sociological reframing of body image, foregrounding the social and cultural dimensions which are critical in shaping young people¿s everyday bodily experiences. Chapters explore the significance of ¿gender¿ and ¿wellbeing¿ norms and the ways that circumstances of hardship and inequality are significant in mediating body concerns. In this, the book complicates simplistic understandings of body image, instead showing the complex processes by which body concerns are formed through the circumstances of embodied experience. The book advocates for the non-individual dimensions of body concerns¿the social and cultural conditions of young people¿s lives¿to be foregrounded in strategies aimed at addressing this complex youth wellbeing issue. This text will be of interest to scholars in gender studies, youth studies, and feminist sociology.

The book attempts to understand the myriad roles of ballistic and cruise missiles in international security. They are for combat purpose, deterrence, coercive diplomacy and power and prestige of a state. The book also studies missile developments across the world. The book also aims to fathom the various possibilities to reduce the threat from missile systems.