Books published by Springer Nature Singapore

Outstanding Problems in Cancer Risk Assessments: Pharmacodynamic Models for Cancer Risk Assessment; S.H. Moolgavkar. Oncogenes: Review of Current Status and Potential for Contributions to Cancer Risk Assessment Methods: Oncogene Assessment and Human Cancer; D.A. Spandidos, M.L.M. Anderson. Transgenics: Review of Current Status and Potential for Contributions to Cancer Risk Assessment Methods: Oncogenic Transgenic Mice in the Study of Carcinogenesis; C.H. Ahn, W.C. Choi. Case Studies: Review of Methylene Chloride Cancer Risk Assessment: Cancer Dose-Response Modeling and Methylene Chloride; G. Charnley. Case Studies: Review of Benzene Cancer Risk Assessment: Risk Assessments for Benzene-Induced Leukemia; K.S. Crump. Concluding Remarks: Findings and Recommendations; C. Zervos. Index.

The Mutator Transposable Element Family of Maize.- Protein Phosphorylation and the Regulation of Cellular Processes by the Homologous Two-Component Systems of Bacteria.- The Peculiar Nature of Codon Usage in Primates.- The Role of Nodulation Genes in Bacterium-Plant Communication.- Regulation of Gene Expression by Epidermal Growth Factor.- Machinery for Protein Import into Chloroplasts and Mitochondria.- High-Level Expression of Foreign Genes in Mammalian Cells.- Aromatic Hydrocarbon Degradation: A Molecular Approach.- Employment of Fibroblasts for Gene Transfer Applications for Grafting into the Central Nervous System.- The Molecular Biology of Amino Acid Biosynthesis in Plants.- Genetic Manipulation of Bacillus Thuringiensis Insectidal Crystal Protein Genes in Bacteria.- Progress Towards Gene Targeting in Plants.- Molecular Biology of Mating-Type Determination in Schizophyllum Commune.- Functions of Intracellular Protein Degradation in Yeast.- Transgenic Fish for Aquaculture.

Mesoblast Anlage Fields in the Upper Layer of the Chicken Blastoderm at Stage 5V; H. Bortier, L.C.A. Vakaet. The Avian Marginal Zone and its Role in Early Development; H. Eyal-Giladi. Early Mesoderm Formation in the Mouse Embryo; K.A. Lawson, R.A. Pedersen. Differentiation Capabilities of the Avian Prechordal Head Mesoderm; R. Seifert, et al. On the Differentiation and Migration of the Wolffian Duct in Avian Embryos; M. Jacob, et al. Fibronectins and Embryonic Cell Migration; C. French-Constant, et al. Induction and Pattern Emergence in the Mesoderm; A.G. Jacobson. Segmentation and Compartments in the Vertebrate Embryo; K.M. Bagnall. A Monoclonal Antibody that Reacts with the Ventro-Caudal Quadrant of Newly Formed Somites; J.W. Lash, et al. Relations Between Mesodermal and Neural Segmentation; G.M.W. Cook, R.J. Keynes. Angiogenic Capacity of Early Avian Mesoderm; J. Wilting, et al. 15 additional articles. Index.

Compartmentation in Aromatic Metabolism; F. Hrazdina. Immunolocalization of Flavonoid Conjugates and their Enzymes; R.K. Ibrahim. General Phenylpropanoid Metalbolism; C.J. Douglas, et al. Molecular Biology of Stress-Induced Phenylpropanoid and Isoflavonoid Biosynthesis in Alfalfa; R.A. Dixon, et al. Biosynthesis and Metabolism of Isoflavones and Pterocarpan Phytoalexins in Chickpea, Soybean, and Phytopathogenic Fungi; W. Barz, R. Welle. Flavonoid Synthesis in Petunia Hybrida; A.G.M. Gerats, C. Martin. Flavonoids; D.A. Phillips. Flavonoid Sulfation; L. Varin. Synthesis and Base-Catalyzed Transformations of Proanthocyanidins; D. Ferreira, et al. Enzymatic Synthesis of Gallotanins and Related Compounds G.G. Gross. Enantioselective Separations in Phytochemsitry; L.B. Davin, et al. The Phytochemical Society of North America; S.A. Brown. Index.

Introduction. Historical Overview. Databases: Office Information Systems Engineering (J. Palazzo, D. Alcoba) Artificial Intelligence, Logic, and Functional Programming: A HyperIcon Interface to a Blackboard System for Planning Research Projects (P. Charlton, C. Burdorf). Algorithms and Data Structures: Classification of Quadratic Algorithms for Multiplying Polynomials of Small Degree Over Finite Fields (A. Averbuch et al.). Object Oriented Systems: A Graphical Interactive Object Oriented Development System (M. Adar et al.). Distributed Systems: Preserving Distributed Data Coherence Using Asynchronous Broadcasts (J. Piquer). Complexity and Parallel Algorithms: Parallel Algorithms for NPComplete Problems (M. Robson). Computer Architecture and Networks: The Caracas Multiprocessor System (M. Campo et al.). 30 additional articles. Index.

The Role of Parton Distributions in 200 TeV pp Collisions (W.J. Stirling). Multiparticle Production in Hadronic Interactions at Superhigh Energies (A.B. Kaidalov). Jet Topology and New Jet Counting Algorithms (S. Catani). Chromodynamics of Jets Today and the Day after Tomorrow (V.A. Khoze). High Energy Factorization and Heavy Flavor Production (M. Ciafaloni). Heavy Quark Production in Nucleon Collisions (Yu. Shabelski). Results from the L3 Experiment at LEP (P. Lecomte). Structure Functions at Small x and the Regge Limit in QCD (J. Bartels). Exploring Higgs Bosons/Electroweak Symmetry Breaking Physics at 200 TeV (J.F. Gunion). Baryon Number Violation and Instantons in the Standard Model (V.V. Khoze). Pattern Recognition in High Energy Physics with Neural Networks (C. Peterson). Final States in Small x Processes at Very High Energies (B.R. Webber). Structure Function for Large and Small x (G. Marchesini). 6 additional articles. Index.

Primary Active Transporters: A Plethora of Plant Plasmalemma Proton Pumps (M.R. Sussman). Studies on the Higher Plant CalmodulinStimulated ATPase (D.E. Evans et al.). Secondary Ion and Metabolite Transporters: ProtonSugar Cotransporters in Plants (N. Sauer). Insights into the Structure of the Chloroplast Phosphate Translocator Protein (H. Wallmeier et al.). Channel Proteins: Soybean Nodulin26 (D.P.S. Verma). Putative LType Calcium Channels in Plants (R. Ranjeva et al.). Receptor Proteins: Hormone Perception and Signal Transduction in Aleurone (R. Hooley et al.). The Auxin Receptor (R.M. Napier, M.A. Venis). Protein Targeting and Assembly in Membranes: Sequence Determinants for Protein Import into Chloroplasts and Thylakoid Membrane Protein Assembly (G. von Heijne). 11 additional articles. Index.

High Temperature Materials.- The Frontiers of High Temperature Structural Materials.- Magnetic Properties.- Effect of Long Range Ordering on the Magnetic and Electronic Properties of Some Transition Metal Based Alloys.- Ferromagnetic Behavior pf Pd- and Pt-Based Alloys.- Statistical Mechanics and Thermodynamics.- Monte Carlo Simulation of Order-Disorder Phenomena in Binary Alloys.- Compatibility of Lattice Stabilities Derived by Thermochemical and First Principles.- Order-Disorder Kinetics Studied by the Path Probability Method.- Electronic Theories.- Modeling of Invar Properties from Electronic Structure Calculations.- Angularly Dependent Many-Body Potentials Within Tight Binding Hückel Theory.- Structure and Thermodynamics of SixGe1-x Alloys from Computational Alchemy.- First Principle Calculation of Phase Diagrams.- On the Causes of Compositional Order in the NiPt Alloys.- Low Dimensional Systems.- Ultrathin Films of Transition Metals and Compounds: Electronic Structure, Growth and Chemical Order.- Alloy Surface Behavior: Experimental Methods and Results.- Structural Phase Transformations in Alloys: An Electron Microscopy Study.- Thermodynamics of Surfaces and Interphases.- Spatial Ordering in Bimetallic Nanostructures.- Summary.- Summary Thoughts.

Studies of Reovirus Pathogenesis Reveal Potential Sites for Antiviral Intervention.- Drugs as Molecular Tools.- Genetically Engineered Bacteria to Identify and Produce Antiviral Agents.- Antiviral Agents from Novel Marine and Terrestrial Sources.- Virus Receptors: The Achilles' Heel of Human Rhinoviruses.- Therapeutic Strategies Employing CD4, The HIV Receptor.- Molecular Characterization of HIV-2 (ROD) Protease following PCR Cloning from Virus Infected H9 Cells.- A Novel, Non-Nucleoside Inhibitor of HIV-1 Reverse Transcriptase (Review).- Catalytic Antisense RNA (Ribozymes): Their Potential and Use as Anti-HIV-1 Therapeutic Agents.- Therapies for Hepatitis B Virus: Current Status and Future Possiblities.- A Preliminary Report of a Controlled Study of Thymosin Alpha-1 in the Woodchuck Model of Hepadnavirus Infection.- Delta Virus as a Vector for the Delivery of Biologically Active RNAs: Possibly a Ribozyme Specific for Chronic Hepatitis B Virus Infection.- Inhibition of Herpes Simplex Virus Ribonucleotide Reductase by Synthetic Nonapeptides: A Potential Antiviral Therapy.- Antiviral Effects of Herpes Simplex Virus Specific Anti-Sense Nucleic Acids.- Heterogeneity of a Herpes Simplex Virus Clinical Isolate Exhibiting Resistance to Acyclovir and Foscarnet.- Cellular Metabolism and Enzymatic Phosphorylation of 9-(2-Phosphonylmethoxyethyl) Guanine (PMEG), a Potential Antiviral Agent.- Effect of Herpes Simplex Virus Type 1 Infection on Cytokine Gene Expression in Activated Murine Peritoneal Macrophages.- Procedure for Evaluation of Neutralizing Antibody to Cytomegalovirus in Commercial Intravenous Gamma Globulin Preparations.- Improved Detection of Antibodies to Hepatitis C Virus Using a Second Generation ELISA.- Emerging Trends in the Rapid Detection of Viruses.- DNA Probes for Viral Diagnosis.- Contributors.

Histopathology of Bronchial Asthma; P.K. Jeffery. Airway Neuropeptides; P. Barnes. Potential Role of Mast Cell Proteases in Asthma; J. Nadel. Human Mast Cells, Basophils, and their Mediators; V. Casolaro, et al. Platelets and Asthma; J. Morley, et al. Leukotrienes and Asthma; J. Rokach, et al. Plasma Exudation in Asthma and its Pharmacological Control; C. Persson. Synthesis and Regulation of IgE in Asthma; G. Del Prete. Osmotic and Ionic Factors in Bronchial Responsiveness; S. Bianco, et al. Airway Responsiveness, Late-Phase Response, and Inflammation in Allergic Asthma; V. Brusasco, et al. Injury and Repair of the Airway Epithelium in Asthma; S. Rennard, et al. Bronchial Asthma and Pulmonary Gas Exchange; R.R. Rodriguez. Asthma Management; A. Tattersfield. The National Asthma Education Program; S. Hurd. Management of Asthmatic Children; K.F. Kerrebijn. 12 additional articles. Index.

Introduction: Atomic Physics and Nuclear Properties; J. Bauche. Atomic Methods in Nuclear Spectroscopy: Progress in Atomic Physics Experiments on Nuclear Properties; R. Neugart. Single Particle Aspects: Single Particle Response Function; S. Gales. Multiphonon States: Low-Energy Multiphonon States in Deformed Nuclei; R. Piepenbring. Shapes and Coexistence: Algebraic Approaches to Nuclear Structure; R.F. Casten. Octupoles: Reflection-Asymmetric Shapes in Atomic Nuclei; W. Nazarewicz. Superdeformation: Microscopic Description of Superdeformation at Low Spin; R. Bonche, et al. Exotic Nuclei: Search for New Radioactivities at the Proton-Drip Line; F. Pougheon, et al. Chaos: Quantum Chaos and Low-Energy Nuclear Spectroscopy; M.J. Giannoni. Experimental Techniques: Nuclear Moments by Orientation Methods; H. Postma. 35 additional articles. Index.

Atoms in Intense Laser Fields: Inhibition of Atomic Ionization in Strong Laser Fields; B. Piraux, E. Huens. Optical Analogs of Model Atoms in Fields; P.W. Milonni. Molecules in Intense Laser Fields: Intense Field Dynamics of Diatomic Molecules; L.F. DiMauro, et al. Excitation of Molecular Hydrogen in Intense Laser Fields; H. Helm, et al. High Intensity Molecular Multiphoton Ionization; G.N. Gibson, et al. Atomic Coherences: Coherence in Strong Field Harmonic Generation; A. L'Huillier, et al. Coherent Interactions within the Atomic Continuum; P. Lambropoulos, et al. Molecular Coherences: Femtosecond Pulse Shaping and Excitation of Molecular Coherences; A.M. Weiner, et al. Coherence in the Control of Molecular Processes; P. Brumer, M. Shapiro. Optimal Control of Molecular Motion; H. Rabitz. 25 additional articles. Index.

Regulation of Gene Expression: Regulation of Expression of the Pea Plastocyanin Gene; J.C. Gray, et al. Import of Nuclear-Coded Proteins into Chlorplasts and Mechanism of Chloroplast Protein Translocation: Targeting of Proteins Into and Across the Chloroplastic Envelope; K. Keegstra, et al. Biosynthesis and Origen of Chloroplast Pigments: Pigments of the Plastid Envelope Membranes; J. Joyard, et al. Photosynthetic Unit Assembly and its Dynamic Regulation: Role of the Chloroplast Envelope in Thylakoid Biogenesis; J.K. Hoober, et al. Organization and Interactions of Photosynthetic Units: Organization of the Photosystem II Reaction Center; K. Satoh. Adaptation Mechanisms in Plants and Algae: Modification of Chloroplast Development by Irradiance; A. Melis. Genetic Manipulation as a Means to Monitor Assembly and Function. 80 additional articles. Index.

1 Probability, Pseudoprobability, Mean Values.- 1. Introduction.- 2. Pairs of Operators.- 3. Wigner's Pseudodensity.- 4. Probability Spaces.- 5. Quantum Mechanics and Fluid Dynamics.- 6. Marcinkiewicz Space and Stationary Functions.- 7. Conclusion.- 2 Local Vacua.- 1. From Bell's Theorem to Where?.- 2. Some Basic Facts about Nonlocality.- 3. How to Get Rid of the Wave Function Collapse.- 4. The Physical Nature of the Local Vacuum.- 5. Dirac's Covariant Vacuum as an Example.- 6. Conclusion and Outlook.- 3 Causal Quantum Theory: Why a Nonstarter?.- 1. Introduction.- 2. Formalism and Interpretation: An Example.- 3. The "Copenhagen" Interpretation.- 4. A Logically Possible, Empirically Viable Alternative: Causal Interpretations.- 5. A Modern "Double-Slit" Experiment.- 6. The Value of an Alternative Interpretation.- 7. Oposing Commitments, Opposing Schools.- 7.1. Cultural Milieux.- 7.2. The Wave-Mechanics Route.- 7.3. The Matrix-Mechanics Route.- 8. Forging the "Copenhagen" Interpretation.- 9. An Alternative Historical Scenario?.- 10. Internal versus External Explanations.- 4 Duality of Fluctuations, Fields, and More.- 1. Introduction.- 2. Duality of Fluctuations.- 2.1. Generalized Wave-Particle Fluctuations.- 2.2. Nonclassical States.- 3. Duality of Fields.- 3.1. Classical Fields.- 3.2. Nonclassical Fields.- 3.3. The Vacuum.- 4. Duality of the Radiation Process.- 4.1. Two Kinds of Radiation Processes.- 4.2. Spontaneous Emission.- 4.3. Stimulated Emission.- 4.4. Stimulation (of Induced Emission): The Blake-Scarl Experiment.- 4.5. Stimulation (of Spontaneous Emission).- 4.6. A Hypothesis.- 5. The Unobservable Wave.- 5.1. Empty Waves and Duality.- 5.2. Blake-Scarl.- 5.3. Selleri and Others.- 5.4. Mückenheim et al.- 5.5. Martinolli-Gozzini.- 5.6. Conclusion.- 6. Discussion: Measurement and Duality.- 6.1. Locality.- 6.2. Unitarity.- 6.3. Duality and Reality.- 5 Dualism within Dualism: Open Questions.- 6 Recent Contributions of Electron Interferometry to Wave-Particle Duality.- 1. Introduction.- 2. The Novel Electron-Optical Biprism Interferometer.- 3. Electron Interferometric Verifications of Wave-Particle Duality.- 3.1. Early Experiments: Diffraction at an Edge, Electron Biprism Interferences, and Diffraction by Slits.- 3.2. Novel Experiments.- 7 The Aharonov-Bohm Effect From the Point of View of Local Realism.- 1. Introduction.- 2. Theory of the AB Effect.- 3. Looking Beyond the Mathematical Formalism.- 4. Local Realist Interpretation of the AB Effect.- 8 Are Two-Beam Self-Interferences Mass-Independent? Not Thoroughly Known (?) Role of the Mass.- 1. Introduction and Historical Backgrounds.- 2. Propositions of New Test Experiments.- 2.1. Modified Neutron Double Slits.- 2.2. TSPL versus V Curve.- 2.3. Effect of Source Size.- 2.4. Modified Ion Biprism.- 3. Is the Dirac Assumption Approximate or Not?.- 4. Hypothetical Model: The In-flight Transition before Arrival at Detector.- 5. Theoretical Perspectives.- 5.1. Irreversible Microscopic Process.- 5.2. Effect on EPR and Delayed Choice Experiments.- 5.3. Are Roles of the Mass "Not Thoroughly Known"?.- 6. Epistemological Remarks.- 9 Wave Mechanics and Relativity.- 1. Can We Reach Wave Mechanics Starting from Classical Mechanics?.- 2. Minimal Conditions of Wave-Particle Dualism: They Are Incompatible with Classical Mechanics and Require Relativity.- 3. A Note about a Reasoning of Hamilton.- 10 Unsharp Particle-Wave Duality in Double-Slit Experiments.- 1. Introduction.- 2. The Photon Split-Beam Experiment.- 3. The Unsharp Measuring Process.- 4. Information Theoretical Considerations.- 5. Realization of the Unsharp Joint Measurement of P(A) and P(B).- 6. Neutron Interference Experiments.- 11 Some Arguments against the Existence of de Broglie Waves.- 1. Distinguishing Schrödinger's from de Broglie's Waves.- 2. De Broglie's Initial Concept of de Broglie Waves.- 3. Discussion of Models.- 4. Conclusion.- 12 On the "Completeness" of Quantum Mechanics.- 1. Background.- 2. Covering Theories: An Ex

Combination Immunotherapy: Immune Therapy of Human Cancers (R.P. Gale, A. Butturini). Clinical Applications of Combination Chemoimmunotherapy in Cancer: Combination of Fluorouracil and Interfon (R. Pazdur). Combination Approaches and Gene Therapy in the Treatment of AIDS and Other Infectious Diseases: Combination Therapies with Cytokines and AntiCytokines in Murine Opportunistic Infections (L. Romani et al.). Mechanism of Action and Synergy Between Drugs, Biological Response Modifiers and/or Vaccines in Combination Therapies: The Case for Synergy of Thymic Hormones and Interleukins in Immune Reconstitution (J.W. Hadden et al.). Immune Mediated Tumor Destruction (P.M. Sondel). Prospects and Future Directions Using Animal Models to Define Effective Combination Therapies with Biological Response Modifiers: Cancer Immunotherapy (L. Tentori et al.). 29 additional articles. Index.

Systems and Archives in Astronomy: Astrophysics Data Systems (F. Giovane). MIDAS OnLine at the Telescopes (K. Banse et al.). Astronomical Databases (A. Heck). The HST Mission: The Hubble Space Telescope: Year One (R.J. Hanisch). HST Image Restoration (H.M. Adorf). Detecting Cosmic Rays Hits on HST WF/PC Images Using Neural Networks and Other Discriminant Analysis Approaches (F.D. Murtagh, H.M. Adorf). The ROSAT Mission: Mission Planning with ROSAT (S.L. Snowden, J.H.M.M. Schmitt). The Standard Automatic Analysis Software System (R. Gruber). The GRO Mission: Response Determination of COMPTEL from Calibration Measurements, Models, and Simulators (R. Diehl et al.). The OSSE Data Analysis System (M.S. Strickman). Future Missions: The Extreme Ultraviolet Explorer Mission (C.A. Christian). The SAX Mission (R.C. Butler, L. Scarsi). 24 additional articles. Index.

Atomic Inferometry and Trapping: Quantum Theory of Particle Trapping by Oscillating Fields; R.J. Glauber. Quantum Measurements on Localized Particles; S. Stenholm. Quantum Measurements: PhaseSensitive BackAction on a Microscopic System; V. Bagini, et al. Cavity QED and Classical Antenna Theory; J.P. Dowling. Quantum Noise Reduction and Squeezing: Progress and Perspectives in Squeezing; E. Giacobino, et al. Time-Dependent Invariants and Nonclassical Light; V.I. Man'ko. Optical Propagation, Communication and Imaging: Direct Space Quantum Optics; I. Abram, E. Cohen. Photonic Band Structure; E. Yablonovitch. Photon Interference and Bell's Theorum: What is Two Photons? J.G. Rarity, P.R. Tapster. Quantum Cryptography and Bell's Theorum; A.K. Ekert. Twentyfive additional articles. Index.

Session I: Breastfeeding and Maternal-Neonatal Interactions. Epidemiological Aspects of Breastfeeding.- Characteristics of Human Milk Antibodies and Their Effect in Relation to the Epidemiology of Breastfeeding and Infections in a Developing Country.- T Cell Development in the Fetus and Neonate.- Growth Factors and the Development of Neonatal Host Defense.- Session II: Development of the Neonatal Immune System.- Amniotic Fluid: The First Feeding of Mucosal Immune Factors.- Ontogeny of the Secretory IgA System in Humans.- IgA-Secreting Cells in the Blood of Premature and Term Infants: Normal Development and Effect of Intrauterine Infections.- Development of T Cells with Memory Phenotype in Infancy.- The Effect of Human Milk, Protein-Fortified Human Milk and Formula on Immunologic Factors of Newborn Infants.- Ontogeny of the Mucosal Immune Response in Children.- Session III: Function of Cytokines in the Development of the Immune System.- Are Cytokines in Human Milk?.- The Developing Gastrointestinal Tract and Milk-Borne Epidermal Growth Factor.- Growth Factor Signal Transduction in Human Intestinal Cells.- Role of IL-6 in Human Antigen-Specific and Polyclonal IgA Responses.- Immunological Properties and Differentiation Potential of Human Colostral Lymphocytes of B Cell Lineage.- Session IV: Innate Immune Factors.- The Effects of Colostrum on Neutrophil Function: Decreased Deformability with Increased Cytoskeleton-Associated Actin.- Peroxidases in Human Milk.- Lactoferrin Binding to Its Intestinal Receptor.- Free Fatty Acids and Monoglycerides: Anti-Infective Agents Produced During the Digestion of Milk Fat by the Newborn.- The Role of Milk-Derived Antimicrobial Lipids as Antiviral and Antibacterial Agents.- Anti-Adhesive Molecules in Human Milk.- The Effect of Human Milk on the Adherence of Enterohemorrhagic E. Coli to Rabbit Intestinal Cells.- Session V: Specific Immune Factors.- Identification and Use of Protective Monoclonal IgA Antibodies Against Viral and Bacterial Pathogens.- Production and Use of Monoclonal IgA Antibodies Complexed with Recombinant Secretory Component for Passive Mucosal Protection.- Epithelial Transport of IgA Immune Complexes.- Association of Human Milk SIgA Antibodies with Maternal Intestinal Exposure to Microbial Antigens.- Serum and Breast Milk Antibodies to Food Antigens In African Mothers And Relation To Their Diet.- Modulation of the Immune Response by Maternal Antibody.- Maternal Determinants of Neonatal Immune Response: Effect of Anti-Idiotype in the Neonate.- Immunoglobulin G Subclasses in Human Colostrum and Milk.- Secretory Defenses Against Giardia Lamblia.- Session VI: Antiviral Immunity.- Epidemiological Perspective of Breastfeeding and Acute Respiratory Illnesses in Infants.- Serotypes of Rotavirus That Infect Infants Symptomatically and Asymptomatically.- Immune Response to Rotavirus Vaccines Among Breast-FED and Nonbreast-FED Children.- Recent Advances in Development of a Rotavirus Vaccine for Prevention of Severe Diarrheal Illness of Infants and Young Chiuldren.- Rotavirus Specific Breast Milk Antibody in Two Populations and Possible Correlates of Protection.- Human Milk and HIV Infection: Epidermiologic and Laboratory Data.- Characterization of a Human Milk Factor That Inhibits Binding of HIV GP120 to Its CD4 Receptor.- Breast Milk Transmission of Cytomegalovirus (CMV) Infection.- Antibody Responses to Cytomegalovirus in Serum and Milk of Newly Delivered Mothers.- Protection of Neonatal Mice from Fatal Reovirus Infection by Immune Serum and Gut Derived Lymphocytes.- Passive Immune Protection from Diarrhea Caused by Rotavirus or E. Coli: an Animal Model to Demonstrate and Quantitate Efficacy.- Session VII: Antibacterial Immunity.- The Antibody Response in Infants after Colonization of the Intestine with E. Coli O83. Artificial Colonization Used as a Prevention Against Nosocomial Infections.- Antibodies to Streptococci Pneumoniae in Sera and Secretions of Mothers and Their Infants.- T...

The Developing Brain: The Internal Environment of the Developing Brain; K.M. Dziegielewska, N.R. Saunders. Neuronal Migration and Differentiation During Normal and Genetically-Perturbed Development of the Hippocampal Formation; R.S. Nowakowski. Neurochemical Aspects of the Developing Brain: Dopaminergic Innervation of the Cerebral Cortex; B. Berger. Neuropathological Indicants of Neurodevelopmental Anomalies in Schizophrenics: Clinical and Neurodevelopmental Aspects of Brain Pathology in Schizophrenia; B. Bogerts, P. Falkai. Obstetrical Events and Adult Schizophrenia; K.L. Dykes et al. Structural Imaging and Neuropsychological Evidence of Neurodevelopmental Anomalies: Structural Brain Measurements on MRI Scans in Schizophrenia; H.A. Nasrallah, et al. Morphologic Markers of Neurodevelopmental Paths to Schizophrenia; R.M. Bilder, G.Degreef. Facts About Schizophrenia and Neurodevelopment: Neurodevelopment and Chronological Curiosities of Schizophrenia; P.B. Jones, et al. Three additional articles. Index.

Photophysics: The Nature of the Light Field in Biological Media B.C. Wilson. Photochemistry: Quantum Yield of a Photochemical Reaction; R.H. Potter, et al. Photosensitization: Photosensitization: Reaction Pathways; J.E. van Lier. Photosynthesis: Near Infra-Red Flash Absorption: A Tool for Studying Photosynthesis; P. Mathis, et al. UV Effects: Response to Ultraviolet Radiation in a Simple Eukaryote; (Yeast): Genetic Control and Biological Consequences; D. Averbeck, et al. Environmental Photobiology: Isolation and Biological Consequences of Plant Derived Phototoxins; J.T. Arnason, et al. Vision: Visual Pigments: Absorbance Spectra and Photoproducts; J.K. Bowmaker. Photomorphogenesis: Photomorphogenesis Responses to UV Light: Involvement of Phytochrome and Photoreceptors; B. Lercari. Photomovement: Photomovement; W. Nultsch, et al. Bioluminescence: Bioluminescence: Biochemistry for Fun and Profit; J. Lee. Photomedicine: Photomedicine: Photodermatology B. Johnson. Other Experiments: Experiments Reprinted from The Science of Photobiology, First Edition; K.C. Smith. Appendix: Units of Measure and Conversion Factors. 62 additional articles. Index.

Plant Viruses, Subviral RNAs and Viroids.- Contribution of Plant and Virus Genes to Cauliflower Mosaic Virus Pathogenicity.- Bromovirus RNA Replication and Host Specificity.- Analysis of Tobacco Mosaic Virus-Host Interactions by Directed Genome Modification.- Cell-to-Cell Movement of Plant Viruses.- Tomato Spotted Wilt Virus: A Bunyavirus Invading the Plant Kingdom.- Origin and Evolution of Defective Interfering RNAs of Tomato Bushy Stunt Virus.- Self-Cleavage Activities from Viral Satellite RNAs.- Viroid Structures Involved in Protein Binding and Replication.- Analysis of Viroid Pathogenicity by Genome Modification.- Nitrogen Fixation, Nitrogen Metabolism.- An Extracellular Oligosaccharide Symbiotic Signal Produced by Rhizobium meliloti.- Tissue-Specific Expression of Eariy Nodulin Genes.- Internalization of Rhizobium by Piant Cells: Targeting and Role of Peribacteroid Membrane Nodulins.- Regulation of Nodule Specific Genes.- Regulation of Genes for Enzymes along a Common Nitrogen Metabolic Pathway.- Phytopathology.- Molecular Basis of Plant Defense Responses to Fungal Infections.- Plant Genes Involved in Resistance to Viruses.- Repeated DNA Sequences and the Analysis of Host Specifity in the Rice Blast Fungus.- Molecular Genetics of the Tomato Pathogen Cladosporium fulvum.- Transgenic Potato Cultivars Resistant to Potato Virus X.- Agrobacterium, Transformation.- The Agrobacterium Virulence System.- T-DNA Gene-Functions.- Morphogenetic Genes in the T-DNA of Ri Plasmids.- Transient Expression and Stable Transformation of Maize Using Microprojectiles.- Agroinfection as a Tool for the Investigation of Plant-Pathogen Interactions.- Physical Mapping of the Arabidopsis Genome and its Applications.- Application of Restriction Fragment Length Polymorphism to Maize Breeding.- Soybean Genome Analysis: DNA Polymorphisms are Identified by Oligonucleotide Primers of Arbitrary Sequence.- Genome Analysis in Brassica Using RFLPs.- Physical Mapping of DNA Sequences on Plant Chromosomes by Light Microscopy and High Resolution Scanning Electron Microscopy.- Transposons.- Structure and Function of the Maize Transposable Element Activator (AC).- Expression and Regulation of the Maize Spm Transposable Element.- The En/Spm Transposable Element of Zea mays.- The Mechanism and Control of Tam3 Transposition.- Characterization of Mobile Endogenous Copia-Like Transposable Elements in the Genome of Solanaceae.- Mitochondria, Chloroplasts, Photosynthesis.- Organization and Evolution of the Maize Mitochondrial Genome.- RNA Editing in Wheat Mitochondria: A New Mechanism for the Modulation of Gene Expression.- Topological Orientation of the Membrane Protein URF13.- Cytoplasmic Male Sterility in Petunia.- Nuclear and Chloroplast Genes Involved in the Expression of Specific Chloroplast Genes of Chlamydomonas reinhardtii.- The Thylakoid Membrane of Higher Plants: Genes, their Expression and Interaction.- Greening of Etiolated Monocots - The Impact of Leaf Development on Plastid Gene Expression.- Regulation of Chloroplast Biogenesis in Barley.- Chlorophyll Biosynthesis.- Molecular Approaches to Understand Sink-Source Relations in Higher Plants.- Gene Expression, Photoreceptors.- The Expression of an Ovalbumin and a Seed Protein Gene in the Leaves of Transgenic Plants.- Regulation of Plant Gene Expression by Antisense RNA.- Photocontrol of Gene Expression.- phyA Gene Promoter Analysis.- Approaches to Understanding Phytochrome Regulation of Transcription in Lemna gibba and Arabidopsis thaliana.- Cis-Regulatory Elements for the Circadian Clock Regulated Transcription of the Wheat cab-1 Gene.- Plant Development.- Self-Incompatibility as a Model for Cell-Cell Recognition in Flowering Plants.- Floral Homoeotic and Pigment Mutations Produced by Transposon-Mutagenesis in Antirrhinum majus.- Molecular Analysis of the Homeotic Flower Gene deficiens of Antirrhinum majus.- Mutations of Knotted Alter Cell Interactions in the Developing Maize Leaf.- T-DNA Insertion Mutagen...

Oviductal Recognition of Embryonic Signals; H.B. Croxatto, et al. Effect of Progesterone Antagonists on Ovo-Endometrial Interactions; A. Psychoyos. On the Requirement for Estrogen for Establishing Pregnancy in the Non-Human Primate; N.R. Moudgal. Embryonic Loss and Conceptus Interferon Production; R.M. Roberts. In Vitro Models of Implantation; S.R. Glasser, et al. Uterine EGF Ligand-Receptor Circuitry and Its Role in EmbryoUterine Interactions during Implantation in the Mouse; S.K. Dey, et al. Human Uterine Angiogenic Factor (HUAF). The Role of Lymphohematopoietic Cytokines in Signalling between the Immune and Reproductive Systems; T.G. Wegmann. Human Decidual Function in Trophoblast and Uterine interaction; T. Mori, et al. Cytokines at the Maternal Fetal Interface: Colony Stimulating Factor1 as a Paradigm for the Maternal Regulation of Muridae Rodents; C. Tachi. Hormonal Regulation of Uterine Complement; K.B. Isaacson, et al. Insulinlike Growth Factor Binding Proteins: A Paradigm for Conceptus-Maternal Interactions in the Primate; A.T. Fazleabas, et al. The Roles of Growth Factors and Their Receptors in Peri-Implantation Mouse Embryos and at the Embryomaternal Interface; Z. Werb, et al. Ligands and Receptors of the Insulin Family: Role in Early Mammalian Development; S. Heyner, et al. 6 additional articles. Index.

I. Clinical Topics.- The Clinical Profile of Sepsis and the Adult Respiratory Distress Syndrome.- The Participation of the Complement System in Atherosclerotic Vascular Disease.- The Spectrum of Atherosclerosis in the Human.- Cerebral Endothelial Injury in Stroke, Brain Trauma and Hypertension.- II. General Concepts in Endothelial Cell Pathophysiology.- Free-Radical Mediated Actions on Endothelial Cells of the Intact Lung.- Regulation of Vascular Function by Vascular Permeability Factor.- III. Chemical Mediators of Endothelial Cell Injury.- Endothelial Cells as Targets for and Producers of Cytokines.- Roles of Vascular Cells in Inflammation and Immunopathology.- The Biochemistry, Cell and Molecular Biology of Type 1 Plasminogen Activator Inhibitor.- IV. Endothelial Cell Interaction with Blood Components.- Purine Regulation of Endothelial Cells: Relevance to Pathophysiology.- Autoantibodies to Endothelial Cells.- Leukocyte-Endothelial Cell Interactions.- V. Vascular Responses to Endothelial Cell Injury.- Endothelial Function in Human Coronary Bypass Grafts.- Altered Renovascular Endothelial Functions During Nephrotoxicity.- Cerebral Endothelial Function: Physiology and Pathophysiology.- Mechanisms of Altered Reactivity in the Cerebral Microcirculation.- VI. Mechanisms of Endothelial Cell Dysfunction.- The Role of Apolipoprotein E and Apolipoprotein B in Atherosclerosis.- Endothelial Cell-Matrix Interactions in Health and Disease.- Biosynthesis and Assembly of von Willebrand Factor by Vascular Endothelial Cells: Relevance to Pathophysiology.- VII. Markers of Endothelial Cell Injury and Repair.- Monitoring of Endothelial Plasmalemmal Ectoenzyme Function as an Index of Endothelial Injury and Repair.- Pathophysiological Significance of Endothelial Cell Integrins.- VIII. Epilogue.- Vascular Endothelium: Physiological Basis of Clinical Problems.- IX. Abstracts of Oral and Poster Presentations.- X. List of Participants.- XI. Index.

Shear Flows: Experimental Observations: The Mixing Transition in Free Shear Flows; A. Roshko. Vortex Shedding from Spheres at Subcritical Reynolds Number in Homogeneous and Stratified Fluid; P. Bonneton, et al. Nature of the Görtler Instability: A Forced Experiment; J.M. Chomaz, et al. Control Experiments: Control of Turbulent Shear Flows via Stationary Boundary Conditions; H.E. Fielder, et al. The Effects of External Excitation on the Reynolds-Averaged Quantities in a Turbulent Wall Jet; E. Horev, et al. Control of Organized Structures in Round Jets at High Reynolds Numbers; P.J.D. Juvet, et al. Numerical Experiments: Advances and Some Novel Experiments using Direct Numerical Simulations of Turbulence; P. Moin. Bubble Formation in Dense Fluidized Beds; J.A. Hernández, et al. Three Dimensional Numerical Simulations of Coherent Structures in Free Shear Flows; M. Lesieur, et al. Closed Flows: Experiments: Effect of Noise on Bifurcations and Patterns in Dissipative Systems; G. Ahlers. Hexagonal Convective Cells; C. Pérez-García, et al. Theoretical Models: The NS and Related Equations: Vortex Dynamics and Turbulence; P.G. Saffman. Control of Boundary Layer and Dynamical Systems Theory: An Update; G. Berkooz, et al. 19 additional articles. Appendices. Index.

Session I.- Molecular Analysis of H23 Epithelial Tumor Antigen - Differentially Spliced Full Length cDNAs and Gene.- Characterization and Evolution of an Expressed Hypervariable Gene for Tumor-Associated Mucin, MUC-1.- Structure, Processing, Differential Glycosylation and Biology of Episialin.- Molecular Cloning and Expression of Breast Mucin-Associated Antigens.- Monoclonal Antibodies Reactive with Breast Cancer, Mammary Mucins and Synthetic Peptides.- Molecular Analysis of Epitopic Heterogeneity of the Breast Mucin.- Session II.- Expression and Prognostic Significance of the Her-2/NEU Oncogene During the Evolutionary Progression of Human Breast Cancer.- Structure and Function of MFG-E8: A Novel Apical Membrane Protein of Mouse Mammary Ephelial Cells.- Targeted Lysis of Human Breast Cancer Cells by Human Effector Cells Armed with Bispecific Antibody 2B1 (ANTI-c-erbB-2/ANTI-Fcy Receptor III).- Mechanisms Controlling Steroid Receptor Binding to Specific DNA Sequences.- Session III.- Origin and Nature of the Milk Lipid Globule Membrane.- N-Linked Oligosaccharide Synthesis and Cellular Sociology.- Development of Enzyme Immunoassays for Breast Carcinoma-Associated Mucin Antigens.- Clinical Studies and New Developments with Hybri-BREScan (CA-549), A Monoclonal Assay for Breast Cancer-Associated Antigen.- Evaluation of Several Tumor Markers (MCA, CA 15.3, BCM and CA 549) in Tissue and Serum of Patients with Breast Cancer.- IMx BCM: A Novel Monoclonal Based System for the Detection of Breast Cancer Associated Mucin.- A Novel Serum Assay Using Recombinant Breast Epithelial Mucin Antigen.- Session IV.- RadioimmunoguidedTM Surgery in Breast Cancer.- Immuno-Pharmacologic Purging of Breast Cancer from Bone Marrow.- Imaging, Pharmacokinetics, Dosimetry and Antitumor Effects of Radiolabeled Anti-Breast Cancer Antibodies in Mouse and Man.- Radioimmunotherapy with I-131 Chimeric L-6 in Advanced Breast Cancer.- Contributors.

Changing Trends of Diagnostic Virology in a Tertiary Care Medical Center.- Evaluation of Electron Microscopic Information Available from Clinical Samples.- Detection of Viral Sequences in Formalin Fixed, Paraffin Embedded Tissues from HIV-1 Infected Patients Using the PCR.- Detection of Viral Nucleic Acids by Q? Replicase Amplification.- Determinants of Measles Mortality: Host or Transmission Factors?.- The International Epidemiology of HIV-1 Infections.- Human Herpesvirus 6: An Update.- Papillomaviruses and Human Cancer.- Detection and Elimination of Blood-Borne Viruses Transmitted by Transfusion.- Programmed Antigenic Stimulation - A New Approach to Influenza Vaccination.- Lessons from Varicella Vaccine.- Antisense Oligonucleotides as Anti-Viral Agents: New Drugs for a New Age.- Abstracts.- Contributors.- Author Index.