Books published by Springer Nature Singapore

Presenting patient- and problem-oriented review articles, this series is designed to keep the internist, general surgeon, and specialist in gastroenterology and hepatology abreast of the latest advances in the field.

1. Metabolism of Ethanol.- 1.1. Pathways of Ethanol Oxidation.- 1.2. Alteration in the Metabolism of Ethanol after Chronic Ethanol Consumption.- 1.3. Effects of Liver Disease, Blood Flow, Circadian Rhythm, Gender, and Other Factors on Hepatic Alcohol Metabolism.- 1.4. Effects of Other Drugs on Ethanol Metabolism.- 1.5. Ethnic and Genetic Factors in Ethanol Metabolism.- 1.6. Extrahepatic Ethanol Metabolism.- 1.7. Summary.- References.- 2. Acetaldehyde and Acetate.- 2.1. Pathways of Acetaldehyde and Acetate Metabolism.- 2.2. Effect of Chronic Ethanol Consumption on Acetaldehyde and Acetate Metabolism.- 2.3. Effect of Liver Injury on Acetaldehyde Metabolism.- 2.4. Effects Attributable to Acetaldehyde and Acetate after Acute and Chronic Ethanol Consumption.- 2.5. Summary.- References.- 3. Alcohol, Hormones, and Metabolism.- 3.1. Hypothalamic-Pituitary-Thyroidal Axis.- 3.2. Parathormone and Calcitonin.- 3.3. Adrenocortical Function: Glucocorticoid Secretion.- 3.4. Adrenocortical Function: Mineralocorticoid Secretion.- 3.5. Adrenal Medullary Function.- 3.6. Growth Hormone.- 3.7. Antidiuretic Hormone and Oxytocin.- 3.8. Pancreatic and Gastrointestinal Hormones.- 3.9. Alteration of Carbohydrate Metabolism by Alcohol.- 3.10. Effects of Ethanol on Ketone Metabolism.- 3.11. Alcoholic Ketoacidosis.- 3.12. Hyperlactacidemia and Lactic Acidosis.- 3.13. Alcoholic Hyperuricemia and Its Relationship to Gouty Attacks.- References.- 4. Ethanol and Lipid Disorders, Including Fatty Liver, Hyperlipemia, and Atherosclerosis.- 4.1. Interaction of the Metabolism of Ethanol and Lipids.- 4.2. Pathogenesis of the Alcoholic Fatty Liver.- 4.3. Agents and Procedures that Prevent the Alcoholic Fatty Liver.- 4.4. Effects of Ethanol on Blood Lipids: Characteristics and Pathogenesis of Alcoholic Hyperlipemia.- 4.5. Ethanol, Atherosclerosis, and High-Density Lipoproteins.- 4.6. Interaction of Ethanol with Vascular Prostacyclin Production.- 4.7. Summary.- References.- 5. Effects of Ethanol on Amino Acid and Protein Metabolism.- 5.1. Effects of Ethanol on Nitrogen Balance and Body Protein Composition.- 5.2. Effects of Ethanol on Amino Acids.- 5.3. Effects of Ethanol on Hepatic Protein Synthesis.- 5.4. Effects of Ethanol on Hepatic Protein Secretion.- 5.5. Effects of Ethanol on Hepatic Protein Catabolism.- 5.6. Hepatic Accumulation of Protein after Chronic Ethanol Feeding.- 5.7. Dietary Requirements for Protein in the Alcoholic.- 5.8. Summary.- References.- 6. Interaction of Ethanol with Other Drugs.- 6.1. Interaction with Drug Absorption.- 6.2. Interaction with Plasma Protein Binding.- 6.3. Interaction with Hepatic Blood Flow.- 6.4. Interaction with Hepatic Cell Uptake.- 6.5. Interaction with Hepatic Metabolism.- 6.6. Pharmacological Interactions.- 6.7. Summary and Therapeutic Guidelines.- References.- 7. Alcohol and the Liver.- 7.1. Epidemiology of Alcoholic Liver Disease.- 7.2. Pathology and Symptomatology of the Various Stages of Alcoholic Liver Injury.- 7.3. Pathogenesis of Alcoholic Liver Injury.- 7.4. Diagnosis of Alcoholic Liver Injury.- 7.5. Prognosis and Treatment of Alcholic Liver Injury.- References.- 8. Alcohol and the Hematologic System.- 8.1. Red Cells.- 8.2. Platelets.- 8.3. Granulocytes.- 8.4. Monocytes and Macrophages.- 8.5. Lymphocytes.- 8.6. Other Factors Favoring Infection.- 8.7. Summary.- References.- 9. Immunologic Reactions in Alcoholic Liver Disease.- 9.1. Morphological Considerations.- 9.2. Genetic Factors.- 9.3. Immunoglobulins, Antibodies, and Immune Complexes.- 9.4. Hepatitis B Virus (HBV).- 9.5. Hepatitis C Virus (HCV).- 9.6. Serum Factors and Cytokine Activity.- 9.7. Cell-Mediated Alterations.- 9.8. Abnormal Antigen Expression on Liver Cells.- 9.9. Alcohol and Alteration of the Immune Response in Alcoholics without ALD.- 9.10. Summary.- References.- 10. Alcohol and the Digestive Tract.- 10.1. Introduction.- 10.2. Oropharynx and Salivary Glands.- 10.3. Esophagus.- 10.4. Stomach.- 10.5. Effect of Alcohol on the Small Intestine.- 10.6...

1: Production and Seed Improvement.- 1 Rapeseed and Canola: Global Production and Distribution.- 2 North American Production of Canola.- 3 Agronomy of Canola in the United States.- 4 New Developments in Canola Research.- 5 The Role of Biotechnology in Canola/Rapeseed Research.- 2: Chemistry, Analysis, and Nutritional Effects.- 6 Canola Fatty Acids-An Ideal Mixture for Health, Nutrition, and Food Use.- 7 Stability of Canola Oil.- 8 Hydrogenation of Canola Oil.- 9 Glucosinolates: Structure-Properties-Function.- 10 Phytates in Canola/Rapeseed.- 11 Phenolic Acids and Tannins in Rapeseed and Canola.- 12 Carbohydrates of Canola and Rapeseed.- 13 Application of Near Infrared to the Analysis of Oil, Protein, Chlorophyll, and Glucosinolates in Canola/Rapeseed.- 3: Commercial Processing and New Developments.- 14 Commercial Processing of Canola and Rapeseed: Crushing and Oil Extraction.- 15 Further Processing of Canola and Rapeseed Oil.- 16 Enzyme Pretreatment to Enhance Oil Extractability in Canola.- 17 Removal of Glucosinolates and Other Antinutritients from Canola and Rapeseed by Methanol/Ammonia Processing.- 18 Ultrafiltration in Rapeseed Processing.- 19 Aqueous Enzymatic Processing of Rapeseed for Production of High Quality Products.

The themes of migration and economic development are traditionally related. The debate on these issues has recently gained much relevance, particularly in Europe, as the phenomenon of migration tends to be seen as a possible consequence (and cause) of political and environmental unrest. This volume is an important contribution to the move towards migration policies which increase total welfare, both in the host countries and in the countries of origin. It also explains problems specific to Europe and stresses the need for coordinated national policies.

I: Perfumery as An Art.- 1: The Art of Perfumery.- II: Perfumery as A Topic in Life Sciences.- 2: Odours and Perfumes as a System of Signs.- 3: Semiochemicals: Mevalogenins in Systems of Chemical Communication.- 4: Origin of Natural Odorants.- 5: A Consideration of Some Psychological and Physiological Mechanisms of Odor Perception.- III: Trapping and Measuring of Odours.- 6: The Measuring of Odors.- 7: Trapping, Investigation and Reconstitution of Flower Scents.- IV: Classification of Odours.- 8: Empirical Classification of Odours.- 9: Chemical Classification and Structure-Odour Relationships.- V: Compository Techniques and Application Segments.- 10: Creative Perfumery: Composition Techniques.- 11: Support Materials for Odorant Mixtures.- 12: Perfumery Applications: Functional Products.- 13: The Impact of Market Research.- VI: Production of Perfumes.- 14: The Chemistry of Synthetic Raw Materials Production.- 15: Compounding.- 16: The Toxicology and Safety of Fragrances.- 17: The Fragrance Industry in a Changing World.- VII: Topics in Perfumery Research.- 18: Receptors: Current Status and Future Directions.- 19: Natural Products.- 20: Synthetic Products.- Outlook.- List of Contributors.

Hemostatis and Desmopressin: Molecular Mechanisms of Cellular Responses to DDAVP; S. Hashemi, et al. Pharmacology and Pharmacodynamics of Desmopressin: Toxicity of Desmopressin and Related Peptides; L.B. Kinter, et al. Desmopressin in Renal Disease: Control of Bleeding in Uremic Patients; Y. Sultan. Desmopressin and Platelets: Desmopressin in the Treatment of Congenital and Acquired Defects of Platelet Function; M. Cattaneo, P.M. Mannucci. Desmopressin and Surgery: Desmopressin, von Willenbrand Factor, and Surgery; M. Weinstein. Desmopressin and Blood Donation: Effects of Desmopressin on Normal Donors in Plasma Exchange Donations; R.J. Sassetti, B.C. McLeod. Clinical Applications of Desmopressin in Hemophilia and von Willenbrand's Disease: Intravenous and Subcutaneous Desmopressin; M. Kohler, G. Mariani. SideEffects and Adverse Reactions of Desmopressin: DDAVP and Tachyphylaxis in Healthy Subjects; V. Vicente, et al. Recapitulation: General Recapitulation and Search for a Consensus; P.M. Mannucci, et al. 33 additional articles. Index.

Structure of a Human Rhinovirus Complexed with its Receptor Molecule; N.H. Olson, et al. Cascade Regulation of Vaccinia Virus Gene Expression; B. Moss. Transcriptional Activation by the Adenovirus E1A Proteins; B.A. Lewis, T. Shenk. Mechanisms Regulating Nucleocapsid Formation of the Hepatitis B Viruses; R. Bartenschlager, H. Schaller. Transcriptional Activation by the Hepatitis B Virus X Protein; R. Lucito, R.J. Schneider. Transcription Factors of the ETS Family; K. Macleod, et al. Structure and Function of the Vesicular Stomatitis Virus RNA-Dependent RNA Polymerase; S. Barik, et al. RNA Synthesis and mRNA Editing in Paramyxovirus Infections; J. Curran, et al. Translational Regulation by Reovirus Structural Proteins; A.J. Shatkin, et al. The Regulation of Coronavirus Gene Expression; S.G. Siddell. Aspects of the Molecular Biology of Poliovirus Replication; J. Harber, E. Wimmer. 9 additional articles. Index.

Bioremediation - the use of microorganisms for environmental clean-up - is a technology that is experiencing a rapid phase of development. From the opening chapter of Perspectives in Bioremediation, on the nature of environmental site assessment, on to the genetic manipulation of native soil microorganisms, the international collection of authors provide an understanding of the current progress and limitations of technologies that are designed to help nature herself. The book draws together many different aspects of environmental remediation: the environmental engineer is introduced to the bacteria of contaminated environments and the ideas developing from genetic engineering; the environmental microbiologist can grasp site assessment and the predictive kinetic analysis of potentials. The book provides a clear and concise introduction to the nature of and potential for bioremediation to contribute to a critical global effort in eliminating contamination of the world's resources and to start to reverse decades of environmental mismanagement and neglect.