Books published by Springer Verlag, Singapore

This book addresses various aspects of acoustic¿phonetic analysis, including voice quality and fundamental frequency, and the effects of speech fluency and non-native accents, by examining read speech, public speech, and conversations. Voice is a sexually dimorphic trait that can convey important biological and social information about the speaker, and empirical findings suggest that voice characteristics and preferences play an important role in both intra- and intersexual selection, such as competition and mating, and social evaluation. Discussing evaluation criteria like physical attractiveness, pleasantness, likability, and even persuasiveness and charisma, the book bridges the gap between social and biological views on voice attractiveness. It presents conceptual, methodological and empirical work applying methods such as passive listening tests, psychoacoustic rating experiments, and crowd-sourced and interactive scenarios and highlights the diversity not only of the methods usedwhen studying voice attractiveness, but also of the domains investigated, such as politicians¿ speech, experimental speed dating, speech synthesis, vocal pathology, and voice preferences in human interactions as well as in human¿computer and human¿robot interactions. By doing so, it identifies widespread and complementary approaches and establishes common ground for further research.

This book addresses various aspects of acoustic¿phonetic analysis, including voice quality and fundamental frequency, and the effects of speech fluency and non-native accents, by examining read speech, public speech, and conversations. Voice is a sexually dimorphic trait that can convey important biological and social information about the speaker, and empirical findings suggest that voice characteristics and preferences play an important role in both intra- and intersexual selection, such as competition and mating, and social evaluation. Discussing evaluation criteria like physical attractiveness, pleasantness, likability, and even persuasiveness and charisma, the book bridges the gap between social and biological views on voice attractiveness. It presents conceptual, methodological and empirical work applying methods such as passive listening tests, psychoacoustic rating experiments, and crowd-sourced and interactive scenarios and highlights the diversity not only of the methods used when studying voice attractiveness, but also of the domains investigated, such as politicians¿ speech, experimental speed dating, speech synthesis, vocal pathology, and voice preferences in human interactions as well as in human¿computer and human¿robot interactions. By doing so, it identifies widespread and complementary approaches and establishes common ground for further research.

This book discusses a broad range of basic and advanced topics in the field of protein structure, function, folding, flexibility, and dynamics. Starting with a basic introduction to protein purification, estimation, storage, and its effect on the protein structure, function, and dynamics, it also discusses various experimental and computational structure determination approaches; the importance of molecular interactions and water in protein stability, folding and dynamics; kinetic and thermodynamic parameters associated with protein-ligand binding; single molecule techniques and their applications in studying protein folding and aggregation; protein quality control; the role of amino acid sequence in protein aggregation; muscarinic acetylcholine receptors, antimuscarinic drugs, and their clinical significances.Further, the book explains the current understanding on the therapeutic importance of the enzyme dopamine beta hydroxylase; structural dynamics and motions in molecularmotors; role of cathepsins in controlling degradation of extracellular matrix during disease states; and the important structure-function relationship of iron-binding proteins, ferritins. Overall, the book is an important guide and a comprehensive resource for understanding protein structure, function, dynamics, and interaction.

This book features a collection of extended papers based on presentations given at the SimHydro 2019 conference, held in Sophia Antipolis in June 2019 with the support of French Hydrotechnic Society (SHF), focusing on ¿Which models for extreme situations and crisis management?¿ Hydraulics and related disciplines are frequently applied in extreme situations that need to be understood accurately before implementing actions and defining appropriate mitigation measures. However, in such situations currently used models may be partly irrelevant due to factors like the new physical phenomena involved, the scale of the processes, and the hypothesis included in the different numerical tools. The availability of computational resources and new capacities like GPU offers modellers the opportunity to explore various approaches to provide information for decision-makers. At the same time, the topic of crisis management has sparked interest from stakeholders who need to share a commonunderstanding of a situation. Hydroinfomatics tools can provide essential information in crises; however, the design and integration of models in decision-support systems require further development and the engagement of various communities, such as first responders. In this context, methodologies, guidelines and standards are more and more in demand in order to ensure that the systems developed are efficient and sustainable.Exploring both the limitations and performance of current models, this book presents the latest developments based on new numerical schemes, high-performance computing, multiphysics and multiscale methods, as well as better integration of field-scale model data. As such, it will appeal to practitioners, stakeholders, researchers and engineers active in this field.