Books published by Springer

This book provides a comprehensive overview of skeletal muscle structure, function, and regulation at the cellular and molecular levels. In addition, the book covers various topics, such as muscle contraction, energy metabolism, fatigue, adaptation, and plasticity. This book discusses skeletal muscle anatomy and histology and then covers muscle contraction's molecular and cellular mechanisms. Also, it includes an in-depth discussion of the sarcomere, the basic unit of muscle contraction, and the role of calcium in the process of muscle contraction.This book also explores the energy metabolism of skeletal muscle, including the role of ATP, glycogen, and fatty acids in providing energy for muscle contraction. Additionally, the book covers the mechanisms of fatigue, including peripheral and central factors contributing to muscle fatigue.Other topics covered include muscle adaptation to exercise, the molecular and cellular mechanisms of muscle hypertrophy and atrophy, and the influence of age, sex, and disease on skeletal muscle function.Overall, Skeletal Muscle Physiology: An Update to Anatomy and Function thoroughly explores the structure and function of skeletal muscle, making it an essential resource for students and professionals in exercise science, sports medicine, and physiology.The auto-summaries have been generated by a recursive clustering algorithm via the Dimensions Auto-summarizer by Digital Science handled by Subject Matter Experts and the external editor. The editor of this book selected which SN content should be auto-summarized and decided its order of appearance. Please be aware that the auto-summaries consist of original sentences, but are not representative of its original paper, since we do not show the full length of the publication. Please note that only published SN content is represented here, and that machine-generated books are still at an experimental stage.

This anthology is a manifold combining semiotics and psychology. Chapters in the book are authored by young scholars making sense of semiosis in irreversible time from a multitude of perspectives. The central focus on the dynamics of meaning-making comes together in a variety of topics that align in the core idea of dynamic nature of human making and use of signs. First, this book gives a comprehensive overview of relational dynamics of the sign. The overview is followed by a collection of chapters focusing on various topics relevant for humanities and social sciences, such as experience of time, (cultural) memory, musical signification, human-computer interactions, death and eternity, freedom and responsibility, authenticity, methods for practice and research in psychology, etc. This anthology contributes to the integration of the fields of semiotics and psychology, building on the classic traditions of the Tartu-Moscow School of Semiotics (established by Juri Lotman) and contemporary cultural psychology that has unified social sciences in the recent three decades. Examples of how new semiotic models are applied to various domains of human lives will be given, anticipating the future and addressing its past. As such, this book is a relevant read for everyone interested in the complex nature of meaning-making, and inclusion of dynamics in all expressions of life, including academic research.

This book provides a clear, concise and easy to understand guide to the diagnosis and management of strabismus. Throughout the text, a practical approach to examining, diagnosing and treating patients with strabismus is utilised, supported with case studies in the form of patient photographs and ocular motility videos. Flowcharts and tables are included, together with evidence based management plans and suggestions for further reading. Simplifying Strabismus: A Practical Approach to Diagnosis and Management, 2nd Edition has been fully revised and features a new chapter on strabismus surgery. This book will be an essential resource for optometrists, junior and senior ophthalmologists, as well as any medical professional wishing to improve their knowledge of strabismus.

This book is an outcome of the 37th International Conference EnviroInfo 2023, held at the Leibniz Supercomputing Centre (Munich, Germany), organized by the technical committee for Environmental Informatics of the German Informatics Society. It explores the fusion of information and communication technologies with environmental sustainability. As a flagship edition of the EnviroInfo conference series, it showcases the latest advancements in applied informatics and environmental informatics.With a focus on "Towards a Sustainable Digital Society," the conference presents innovative research on topics such as green computing, sustainable software engineering, and digital transformation. The proceedings cover essential subjects for shaping a greener future, including energy-efficient workloads, environmental management systems, legal frameworks, Earth observation, and geographical information systems. It also examines emerging technologies like robotics, AI, and reinforcement learning, highlighting their applications in environmental informatics.From citizen science to disaster risk modeling and sustainable resource management, the book explores the interdisciplinary nature of environmental informatics. It also addresses societal aspects, including its role in developing countries. This resource is essential for researchers, professionals, and policymakers seeking to leverage ICT for addressing environmental challenges and building a sustainable digital society.

This volume demonstrates advanced strategies in biomedical sciences and healthcare focused on suboptimal health conditions in the framework of Predictive, Preventive and Personalised Medicine (3PM/PPPM). Potential benefits in healthcare systems and for society at large include but are not restricted to an improved life-quality of major populations and socio-economical groups, advanced professionalism of healthcare-givers and sustainable healthcare economy. ​Reactive medical services applied to healthcare resulted in epidemics of non-communicable diseases such as diabetes mellitus type 2 with currently about a half of billion patients registered worldwide. Far-reaching consequences are cascading co-morbidities with poor prognosis such as severe cardiovascular and neurological disorders, eye pathologies (e.g., proliferative diabetic retinopathy as the world leading cause of blindness) and several types of cancer, amongst others. Corresponding socio-economic burden istremendous. The paradigm changes from reactive medicine to PPPM propagated by EPMA is, therefore, pivotal for advanced healthcare to improve the economy of medical services, life quality of populations and individual outcomes. To this end, individuals with suboptimal health condition comprise the target group for predictive diagnostics and cost-effective personalised treatments to protect affected individuals and sub-populations against health-to-disease transition, a window of opportunity for PPPM. This goal is of highest priority benefiting millions of people and societies at large.

This book discusses many issues related to the impact of advanced technologies on quality of human life. It covers several areas and use cases that illustrate how technologies could be harnessed to solve all kinds of humanity issues in areas as diverse as education, health care, industry, agriculture, mobility, etc. Specially, it aims at establishing the vital link between advances in technology and sustainable development to magnify the benefits. This book covers a wide range of audience including academic/research, professors, scientists, and engineers working in different fields, comprising engineering, sustainability, as well as government and international organizations officials interested in sustainable planning. This is done through a set of selected papers from those presented to 4th International Conference on Advanced Technologies for Humanity (ICATH'2022) which was organized by the Moroccan School of Engineering Sciences (EMSI) in collaboration with national and international institutions. ICATH22 was held in Marrakech, from November 11 to 12, 2022. Key topics showcasing how technology can serve humanity in different ways and facets of human life, activities, and challenges are covered in depth through the chapters of this book which are presented in four different sections, namely: 1. Advanced Technologies for smart Mobility in Smart Cities.2. Emerging Technologies for Connectivity in Sustainable Cities.3. Transitioning to Sustainable Industrial Engineering. 4. Technology for Human Sciences as Key Components of Sustainability.

This book contains the proceedings of the 19th Cologne-Twente Workshop on Graphs and Combinatorial Optimization, held during June 20-22, 2023, in Garmisch-Partenkirchen, Germany. This successful series of international workshops is known to attract high-quality research on the theory and application of discrete algorithms, graphs, and combinatorial optimization in a wide sense. The papers collected in this book represent cutting-edge research by leading researchers and attract a broad readership in academia worldwide. The book is addressed to researchers and advanced students, but also to professionals in industry concerned with algorithm design and optimization problems in different areas of application.

This second volume of highly topical two-volume set "The Investment Weapon" continues to present pioneering research for the purpose of developing a common analytical foundation and framework for the emerging interdisciplinary research field of investment control. This second volumes shifts the focus from the policy context to the legal and regulatory aspects of investment controls, specifically from an international, transnational, and comparative law perspective. The topics range from control of subsidized investments to non-national security related investment controls and alternatives to investment screening.

The book's primary objective is to introduce the pathology and physiology atherosclerosis in brief, and its diagnosis and treatment. Atherosclerosis is an inflammatory disease of the arterial wall. An advanced understanding of atherosclerosis shows that it leads to myocardial infarction and other cardiovascular diseases, taking 17 million people every year worldwide. The literature suggests that atherosclerosis is an ancient disease and is still a long-standing health problem globally. Hence early diagnosis and treatment of atherosclerosis are crucial to solving long-standing health issues.This book provides a systemic summary of recent literature focusing on disease pathology, advancement in diagnosis and therapies. Recently, nanoparticles performing dual roles as diagnostic and therapeutic agents have been keenly interested. However, the nanoparticle has yet to reach the clinic. Understanding the role of biomaterials in formulations and existing strategies is critical whendeveloping novel formulations and working on translation to clinical settings. The book provides a systematic biomaterial-based summary of the literature, methods used to formulate nanoparticles, and their scale-up potential. Another key objective of the book is to motivate the reader to conduct research on theranostic nanoparticles to treat atherosclerosis and put us one step closer to solving a long-standing health problem--atherosclerosis.The auto-summaries have been generated by a recursive clustering algorithm via the Dimensions Auto-summarizer by Digital Science handled by Subject Matter Experts and the external editor. The editor of this book selected which SN content should be auto-summarized and decided its order of appearance. Please be aware that the auto-summaries consist of original sentences, but are not representative of its original paper, since we do not show the full length of the publication. Please note that only published SN content is represented here, and that machine-generated books are still at an experimental stage.

This book provides a concise and practical guide for Non-Physician Anaesthesia Providers (NPAPs) such as nurse anaesthetists and Non-Specialist Physicians working in remote settings. In many hospitals in low and even in some middle-income countries, nurse anaesthetists are working without the presence of a specialist anaesthesiologist at their hospital. During their training on the job or at one of the few schools of anaesthesia they have to act as improvising do-it-yourself-teachers for one another. Later in their professional life, NPAPs are often organising their continuous medical education themselves, trying to provide short presentations on topics between attending to patients. This book fills the need for a quick- to-read guide for the everyday work of NPAPs and Non-specialist physician anaesthesia providers, addressing challenges such as electricity failure, lack of technical support, drugs and materials, equipment and support of specialist anaesthesiologists.Anaesthesia in Remote Hospitals: A Guide for Anaesthesia Providers covers the most important fields of anaesthesia in a typical district or referral hospital in a place where resources are limited. It provides many useful tables with doses of drugs, sizes of airway equipment, infusion rate, examples of observation charts and anaesthesia records. Nurse Anaesthetists, Clinical Officers and Resident Physicians will find this book to be an essential guide to Anaesthesia within low resource and remote settings.

This book approaches the field of contrastive linguistics from a comparative and robust perspective that combines the tenets of construction grammar and cognitive linguistics. In doing so, it shows how their integration can help to successfully enhance research on contrastivity, by means of updated theoretical frameworks and applied methodologies that combine language and thought. It compares ten different languages and offers analyses of constructions at all levels of the linguistic organization, identifying the cognitive motivations that instantiate the linguistic data retrieved from corpora. Relevant to both cognitive and non-cognitive linguists interested in variation and contrastive approaches, as well as graduate students in these areas, this book makes a significant contribution to existing work on the various types of constructional and discourse-based phenomena in modern languages.

This book brings together cross-disciplinary research on carbon capture, utilization, and storage (CCUS) to examine the impact of implementing CCUS tools and technologies on emissions reduction and sustainable development in cities and large metropolitan areas. An expert group of global contributors provides in-depth technical discussions, case studies, and examples with an emphasis on the worldwide application of the latest developments in technology, protocols, implementation, and application of CCUS in power and energy systems.Carbon Capture, Utilization, and Storage Technologies: Towards More Sustainable Cities is an essential multidisciplinary reference for researchers and industry practitioners from engineering, energy, computer science, data science, economics, and operational research working in the energy and environmental fields.

This book continues a series of Springer publications devoted to the emerging field of Integrated Artificial Intelligence and Machine Learning with Visual Knowledge Discovery and Visual Analytics that combine advances in both fields. Artificial Intelligence and Machine Learning face long-standing challenges of explainability and interpretability that underpin trust. Such attributes are fundamental to both decision-making and knowledge discovery. Models are approximations and, at best, interpretations of reality that are transposed to algorithmic form. A visual explanation paradigm is critically important to address such challenges, as current studies demonstrate in salience analysis in deep learning for images and texts. Visualization means are generally effective for discovering and explaining high-dimensional patterns in all high-dimensional data, while preserving data properties and relations in visualizations is challenging. Recent developments, such as in General Line Coordinates, open new opportunities to address such challenges.This book contains extended papers presented in 2021 and 2022 at the International Conference on Information Visualization (IV) on AI and Visual Analytics, with 18 chapters from international collaborators. The book builds on the previous volume, published in 2022 in the Studies in Computational Intelligence. The current book focuses on the following themes: knowledge discovery with lossless visualizations, AI/ML through visual knowledge discovery with visual analytics case studies application, and visual knowledge discovery in text mining and natural language processing. The intended audience for this collection includes but is not limited to developers of emerging AI/machine learning and visualization applications, scientists, practitioners, and research students. It has multiple examples of the current integration of AI/machine learning and visualization for visual knowledge discovery, visual analytics, and text and natural language processing. The book provides case examples for future directions in this domain. New researchers find inspiration to join the profession of the field of AI/machine learning through a visualization lens.

This open access book presents a rich set of innovative solutions for artificial intelligence (AI) in manufacturing. The various chapters of the book provide a broad coverage of AI systems for state of the art flexible production lines including both cyber-physical production systems (Industry 4.0) and emerging trustworthy and human-centered manufacturing systems (Industry 5.0). From a technology perspective, the book addresses a wide range of AI paradigms such as deep learning, reinforcement learning, active learning, agent-based systems, explainable AI, industrial robots, and AI-based digital twins. Emphasis is put on system architectures and technologies that foster human-AI collaboration based on trusted interactions between workers and AI systems. From a manufacturing applications perspective, the book illustrates the deployment of these AI paradigms in a variety of use cases spanning production planning, quality control, anomaly detection, metrology, workers' training, supply chain management, as well as various production optimization scenarios. This is an open access book.

This book provides a comprehensive introduction to Generative AI in terms of basic concepts, core technologies, technical architecture, and application scenarios. Readers gain a deeper understanding of the emerging discipline of Generative AI. This book covers the latest cutting-edge application technologies of Generative AI in various fields. It provides relevant practitioners with ideas to solve problems and deepen their understanding of Generative AI. At the same time, it guides and helps Generative AI and related industries to deepen their understanding of the industry and enhance professional knowledge and skills. Starting from reality, this book lists many cases and analyzes theories in a popular image. The book is useful for AI researchers and specifically for those working with the applications at hand (primarily medical imaging and construction/twinning industry). It covers a variety of cutting-edge technologies in Generative AI, which provides researchers with new research ideas.

Dutch scientist Christiaan Huygens (1629-1695) left an indelible mark on the fields of mathematics, physics, astronomy, and geophysics. Despite his groundbreaking contributions, history has often overlooked his pivotal role. While two of the most famous achievements in physics are Newton's theory of gravity and Einstein's general theory of relativity, less well-known is that Huygens provided central elements to these theories. This book stands to correct that deficit. For example, we show how Huygens used symmetry arguments to derive conservation laws for momentum and for energy, and what Einstein later called the principle of equivalence to derive the formula for centrifugal force. In 1689, Huygens visited Newton. Together, they walked the streets of London. Newton had recently finished his masterpiece, Principia, expounding his laws of motion and the law of universal gravitation. Huygens had essentially completed his life's work by then, building on Archimedes, Leonardo da Vinci, Galileo, Descartes, Fermat, Pascal and his own ingenuity. He had established fame as an instrument maker (telescope, pendulum clock, planetarium). He had invented the 31 tone system. He had pioneered the first principles of remote sensing. He had discovered the rings of Saturn. He had formulated the wave theory of light. What would walking with Christiaan reveal? This book gives the result in nine chapters, namely: spontaneous order, the speed of light, Huygens' principle, the telescope, the pendulum clock, Huygens-Fresnel principle, special relativity, centrifugal force, and curvature. In addition, there is a chapter titled What Huygens could have written on diffraction, and a chapter titled Huygens and Geophysics. Mentally walking with Christiaan, browsing his collected works -- a true treasure trove for puzzle enthusiasts -- and rethinking his ideas creates a vivid impression of scientific life in the 17th century, an appreciation that it is remarkably similar to ours, and an understanding of Huygens' significant and lasting contributions to science.

This book embarks on a comprehensive exploration of the jurisdiction of the International Criminal Court (ICC) and elucidates the three foundational aspects of its jurisdiction as laid out in the Rome Statute: the preconditions for exercising jurisdiction (Article 12 ICCRSt), its substantive competence regarding core crimes (Articles 5-8bis ICCRSt), and the principle of complementarity (Article 17§1(a) ICCRSt).This principle, crucial to understanding the ICC's 'ultimate jurisdiction', is invoked only when a State Party demonstrates an inability or unwillingness to genuinely undertake investigation or prosecution. The book further probes the 'negative preconditions' of the Court's jurisdiction, in particular, immunities (Article 27 ICCRSt) and exceptions through Security Council referrals (Articles 13(b) and 15 ICCRSt).Intended for students, scholars, and practitioners alike, this second edition offers invaluable insights into the ICC's jurisdiction, making a notable contribution to the existing literature. Importantly, it also navigates emerging fields of international criminal law, addressing topical and thought-provoking subjects such as ecocide, cyber warfare, automated lethal weapons, artificial intelligence, and the legal complexities arising from the Russian invasion of Ukraine.

This book informs social work students about the context and potential for burnout in their field experience, their first work with clients, and equips them to recognize, prevent, and address it. With its emphasis on role ambiguity and self-care based on current research, the volume uniquely fills the gap in available texts and prepares them for successful professional practice with personal mental health. Job burnout and self-care have received attention in research and education in social work and other caring professions, but social work students must successfully complete managed learning assignments in the field before they can become social workers, and those experiences can put the student at risk for burnout. Until very recently, however, student burnout has been a 'silent' issue in the profession and the literature. With this compact book, readers learn the risks of burnout in field assignments for students and new professionals, the organizational andpersonal factors that contribute to it, appropriate self-care strategies to reduce its incidence, and effective coping strategies to limit its effect. Stakeholders gain understanding about burnout incidence, prevention, and self-care that prepares them to take appropriate preventive and prescriptive action. Burnout in Social Work Field Education: Mitigating the Risk is a timely and essential resource for social work instructors, students, field interns, instructors, and supervisors. It can serve as a supplementary text to aid students in understanding what factors will increase their risk of burnout and help them identify which coping strategies are most likely to be effective, based on research. It is a highly desirable complementary text for adoption in social work courses and in-service education in early social work practice. The book also should interest administrators in social service agencies and presenters of in-service education opportunities for social workers and social work educators.

This book covers the use of computed tomography in trauma care. Over the last two decades, advancements in CT technology have significantly changed the technique and utilization patterns of computed tomography in trauma imaging. This book covers the entire spectrum of this application, structured by organ systems/body areas, corresponding to the subject structure and practice pattern of large academic radiology departments in the US. As a result, the reader benefits from the most advanced currently available sub-specialty expertise in the performance and interpretation of trauma CT studies. The book is intended to serve as an introduction to the subject as well as a reference to the trauma radiologist. Since current post graduate education in radiology does not offer any formally regulated fellowship training in this area, fellowship trained radiologists are typically not trained to cover the entire spectrum of trauma imaging that the practitioner may encounter when covering call assignments, especially outside of highly subspecialized academic medical centers. This book is intended to fill a need to provide subspecialized trauma CT training by integrating contributions from all involved radiology subspecialties in a single volume. This is an ideal guide for radiology residents, fellows, practicing radiologists, trauma surgeons, emergency medicine specialists, surgery residents and fellows, and interested medical students.

This book provides practice questions in a case-based format to prepare for the National Board of Echocardiography¿s examination to assess ¿Special Competence in Critical Care Echocardiography¿.Focused on the exam's core topics, this textbook caters to physicians who are preparing for the Critical Care Echocardiography board examination. Defining features of each chapter include case based scenarios with videos and supporting images, meaningful and relevant multiple-choice questions, key take-aways and a summary. This book is the product of a multidisciplinary collaboration between ICU physicians (Pulmonary, Internal Medicine and Anesthesiology), Cardiologists, and Anesthesiologists.This book meets the needs of physicians from various disciplines preparing for the critical care echocardiography board examination.

This book is composed of a selection of articles from the 11st World Conference on Information Systems and Technologies, held between 4 and 5 of April 2023, at Sant'Anna School of Advanced Studies, in Pisa, Italy. WorldCIST is a global forum for researchers and practitioners to present and discuss recent results and innovations, current trends, professional experiences, and challenges of modern Information Systems and Technologies research, together with their technological development and applications. The main and distinctive topics covered are: A) Information and Knowledge Management; B) Organizational Models and Information Systems; C) Software and Systems Modeling; D) Software Systems, Architectures, Applications, and Tools; E) Multimedia Systems and Applications; F) Computer Networks, Mobility, and Pervasive Systems; G) Intelligent and Decision Support Systems; H) Big Data Analytics and Applications; I) Human¿Computer Interaction; J) Ethics, Computers, and Security; K) Health Informatics; L) Information Technologies in Education; M) Information Technologies in Radiocommunications; and N) Technologies for Biomedical Applications.

This book is composed of a selection of articles from the 11st World Conference on Information Systems and Technologies, held between 4 and 5 of April 2023, at Sant'Anna School of Advanced Studies, in Pisa, Italy. WorldCIST is a global forum for researchers and practitioners to present and discuss recent results and innovations, current trends, professional experiences, and challenges of modern Information Systems and Technologies research, together with their technological development and applications. The main and distinctive topics covered are: A) Information and Knowledge Management; B) Organizational Models and Information Systems; C) Software and Systems Modeling; D) Software Systems, Architectures, Applications, and Tools; E) Multimedia Systems and Applications; F) Computer Networks, Mobility, and Pervasive Systems; G) Intelligent and Decision Support Systems; H) Big Data Analytics and Applications; I) Human¿Computer Interaction; J) Ethics, Computers, and Security; K) Health Informatics; L) Information Technologies in Education; M) Information Technologies in Radiocommunications; and N) Technologies for Biomedical Applications.

This book is composed of a selection of articles from the 11st World Conference on Information Systems and Technologies, held between 4 and 5 of April 2023, at Sant'Anna School of Advanced Studies, in Pisa, Italy. WorldCIST is a global forum for researchers and practitioners to present and discuss recent results and innovations, current trends, professional experiences, and challenges of modern Information Systems and Technologies research, together with their technological development and applications. The main and distinctive topics covered are: A) Information and Knowledge Management; B) Organizational Models and Information Systems; C) Software and Systems Modeling; D) Software Systems, Architectures, Applications, and Tools; E) Multimedia Systems and Applications; F) Computer Networks, Mobility, and Pervasive Systems; G) Intelligent and Decision Support Systems; H) Big Data Analytics and Applications; I) Human-Computer Interaction; J) Ethics, Computers, and Security; K) Health Informatics; L) Information Technologies in Education; M) Information Technologies in Radiocommunications; and N) Technologies for Biomedical Applications.

Pathology of the Achilles tendon is one of the most commonly written about topics in foot and ankle surgery, yet there is no clear consensus on the management of these injuries; in addition, pathologic aspects of the Achilles tendon are not well understood. This up-to-date resource addresses all aspects of Achilles tendon pathology, management, rehabilitation and complications, including novel aspects of Achilles tendon treatment as well as more detail on operative techniques for Achilles tendon surgery. Sensibly divided into four thematic sections, part I presents general considerations such as anatomy and pathology, the physical exam and imaging modalities, and patient-reported outcomes. The following sections describe current management strategies for acute and chronic injuries and complications, respectively. Both nonoperative and operative techniques are highlighted, from minimally invasive techniques to tendinoscopy and open debridementand biological augmentation. Generous intraoperative photos and figures enhance the presentation, and operative algorithms are clearly elucidated. Bringing together the latest in the diagnosis and management of these common injuries, The Achilles Tendon will be a valuable reference for orthopedic foot and ankle surgeons, sports medicine surgeons, podiatrists and fellows and residents in these areas.

This book focuses on devising a comprehensive protective mechanism for the right to privacy in Pakistan. It argues that the existing legal regime lacks an effective remedy for victims of privacy violations and emphasizes the need for comprehensive legislation to safeguard this crucial right. Pursuing a multidisciplinary approach, the book thoroughly explores the issue of media intrusions into people¿s privacy through thematic media content analysis and highlights the significant impacts of these intrusions on victims¿ lives.In the process, the book addresses various conceptual aspects, their relevance, and their implications for privacy-related disputes during adjudication. Recognizing that theoretical underpinnings alone may not be sufficient to create a legal regime ¿from scratch,¿ it explores the enforcement of the right to privacy under the European Convention on Human Rights (ECHR), as interpreted and enforced by the European Court of Human Rights (ECtHR).The book subsequently goes beyond exploring international law by analyzing the impact of media-and-privacy cases on privacy protection in two major member states: Germany (a civil law jurisdiction) and the United Kingdom (a common law jurisdiction). Drawing upon these conceptual and comparative legal deliberations and findings, the book provides concrete guidelines for a new privacy law in Pakistan.

during the different stages of dental implant placement

This new volume provides a scientifically based exploration of the multifaceted world of endogenous opioids, including endorphins, enkephalins, dynorphins, endomorphins, and orphanin FQ/nociceptin, featuring a strong translational focus. Topics covered range from basic scientific investigations, to clinical applications, to investigations in areas such as oncology, childbirth, and disordered eating, to psychosocial contexts such as volunteering and positive emotions. One of the main goals of Endogenous Opioids is to provide recommendations for new directions in medical research and health policy that are rooted in sound scientific research.

This book gives an account of the origins of theoretical mechanics in antiquity, its limited reception in the Arabic and Latin Middle Ages, and its recovery and subsequent development in Italy to the time of Galileo. From late antiquity to the fifteenth century, the ancient science of mechanics--the theory of machines--was almost completely unknown in the Latin west. Then, from the mid-fifteenth century on, Italian humanists began to recover the ancient texts, and from them through the sixteenth century Italian mathematicians restored the ancient science of mechanics. The Renaissance of Mechanics first examines the principal ancient works on mechanics--the Aristotelian Mechanical Problems, the mechanical geometry of Archimedes, and Hero's Mechanics--and then describes their limited reception in the Arabic world and their even more limited transmission to the medieval Latin west. It then traces their recovery in the fifthteenth century and their assimilation inthe sixteenth by Niccolò Tartaglia, Francesco Maurolico, and Guidobaldo dal Monte, culminating in Galileo's rediscovery of Hero's lost mechanical principles. The book ends with an examination of Galileo's mechanics and its relation to his new science of motion, and suggests how modern mechanics would emerge from these ancient roots. Detailed analyses of these works offer new insights and interpretations while remaining accessible to general historians. The Renaissance of Mechanics will be of especial interest to those working in the fields of renaissance humanism and the history of ancient, medieval, and renaissance science and mathematics.

This updated edition of the book provides radiation oncologists with a structured, state-of-the-art guide to target volume delineation for all major cancer types. It provides an overview of recent advances in radiation treatment techniques and multimodal imaging for radiation treatment planning. It also offers clear and structured guidelines for the contouring of target volumes and organs at risk, taking into account the available imaging modalities including PET/CT and multiparametric MR imaging. Each chapter addresses the target volume concepts of a particular tumor type and has been written by experts in the field. Covering all major tumor entities, the book provides practicing radiation oncologists with a guide to defining target volumes based on multimodal imaging.

This open access book (Volume 2) is part of the series "The Physics of Laser Plasmas and Applications." It serves as an introduction to the physics of compressible hydrodynamics, which is used to describe the temporal evolution of plasmas generated by intense laser irradiation of solid surfaces. For the benefit of students and young researchers, the book presents the fundamental equations and provides a comprehensible explanation of solutions to intricate fluid phenomena. It builds upon the concept of plasma generation through the heating of matter via the classical absorption of a laser, as expounded in Volume 1. The high-temperature plasma resulting from the laser interaction manifests in diverse hydrodynamic occurrences like shock waves and expansion waves. The initial sections of this book expound the essentials of compressible hydrodynamics, magnetohydrodynamics (MHD), and the physics of shock waves. The transfer of laser energy within an expanding plasma towards regions of higher density is achieved through electron and X-ray transport mechanisms. In both instances, conventional diffusion models prove inadequate, necessitating mathematical frameworks founded on the Boltzmann equation. The conveyed energy engenders ablation pressure, equivalent to tens of millions of atmospheres, on the solid surface. This pressure initiates powerful shock waves propagating through the solid material. The propagation of these shock waves is delineated for scenarios involving planar and spherical geometries. The text also introduces various solutions pertaining to convergent and divergent shocks in spherical geometries using self-similar models. The discourse then shifts towards ionization and related atomic processes, which govern the dynamics of plasmas created by laser irradiation of mid-Z and high-Z solids. The quantum mechanics of partially ionized atoms and their associated atomic processes are elucidated. Concluding the book is an exploration of the physics of warm dense matter (WDM) - an electron system characterized by quantum-mechanical, many-body interactions. The study of high-density plasmas featuring temperatures around 1 eV is undertaken through the lens of density functional theory (DFT). The theoretical breakdown of experimental data acquired via the X-ray free electron laser (X-FEL) is also provided. In essence, this second volume of the series amalgamates a comprehensive understanding of compressible hydrodynamics, shock wave physics, ionization processes, energy transfer, and the realm of warm dense matter. It equips readers to delve into the intricacies of plasma physics and laser interactions while utilizing modern theoretical frameworks and experimental methodologies.This is an open access book.