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This book describes the status of clinical trials related to siRNA-based cancer therapy, as well as the remaining issues that need to be overcome to establish a successful therapy. It, then introduces various promising design strategies of delivery vehicles for stable and targeted siRNA delivery, including the prospects for future design.
Careful choice of nanoparticles as targets and in drug delivery routes enhances therapeutic efficacy in cancer. This book discusses nanotechnological developments of interfering RNA-based nanoparticles and delivery vehicles, validated therapeutic RNAi-molecular target interactions, and explains the results of clinical and preclinical trials.
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