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Noninferiority Testing in Clinical Trials

- Issues and Challenges

About Noninferiority Testing in Clinical Trials

Requiring no prior knowledge of NI testing, this book explains how to choose the NI margin as a small fraction of the therapeutic effect of the active control in a clinical trial. It discusses issues with estimating the effect size based on historical placebo control trials of the active control. The author covers basic concepts related to NI tr

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  • Language:
  • English
  • ISBN:
  • 9780367576028
  • Binding:
  • Paperback
  • Pages:
  • 208
  • Published:
  • June 29, 2020
  • Dimensions:
  • 156x234x0 mm.
  • Weight:
  • 453 g.
Delivery: 1-2 weeks
Expected delivery: December 8, 2024

Description of Noninferiority Testing in Clinical Trials

Requiring no prior knowledge of NI testing, this book explains how to choose the NI margin as a small fraction of the therapeutic effect of the active control in a clinical trial. It discusses issues with estimating the effect size based on historical placebo control trials of the active control. The author covers basic concepts related to NI tr

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