Books published by Springer Nature Singapore

Introduction: From Fluid Particles to Physical Particles; M. Mareschal, B.L. Holian. Non-Equilibrium Molecular Dynamics: Theoretical Foundation and Rheological Application of NonEquilibrium Molecular Dynamics; G. Ciccotti, et al. Lattice Gases: Lattice Boltzmann Simulation of High Reynolds Number Fluid Flow in Two Dimensions; G. McNamara, B.J. Alder. Other Simulation Methods: A Contemporary Implementation of the Direct Simulation Monte Carlo Method; G.A. Bird. Chaos, Turbulence, and Irreversibility: Lyapunov Exponents and Bulk Transport Coefficients; D. Evans, et al. Related Topics: Statistical Fracture Mechanics; A. Chudnovsky, B. Kunin. Recollections: The Long Time Tail Story; B.J. Adler. 22 additional articles. Index.

The Development of the Vascular System: Embryonic Development of Blood Vessels; F. Dieterlen-Liévre, L. Pardanaud. Regulation of Embryonic Blood Vessel; H. Drexler et al.. Biology of Endothelial Cells and Angiogenesis: Basic Fibroblast Growth Factor and Endothelial Cells; M. Presta, et al. Role of Integrinss in Endothelial Cell Function; E. Dejana, et al. Angiogenesis in Disease States: Angiogenesis and Neoplastic Transformation; P.M. Gullino. Tumor Induced Angiogenesis; J.L. Ambrus, et al. Promoters and Inhibitors of Angiogenesis: Brain Tumor Angiogenesis; C. Guerin, et al. Therapeutic Potential of Promoters and Inhibitors of Angiogenesis: On Promoter of Angiogenesis and Therapeutic Potential; P.M. Gullino. Methodology: Assays for Angiogenic Factors; J.B. Weiss. 23 additional articles. Index.

Introduction; L.C. Chen, et al. Epidemiolgy and Policy: AIDS and Reproductive Health; K. LaGuardia. Policy and Legal Aspects of AIDS Interventions; H. Fineberg. Risk Factors in Transmission: Factors Affecting Female-to-Male Transmission of HIV1; F.A. Plummer, et al. Interrelationships Between HIV Infection and Other STDs; J. Wasserheit. Contraception, Family Planning, and HIV; D. Hunter, J.K.G. Mati. Perinatal Transmission: Mother to Fetus/Infant Transmission of HIV1; O. Meirik. HIV Perinatal Transmission and Reproductive Health; P. Kanki, et al. Methods for Decreasing HIV Transmission to Infants; S.J. Heymann. Interventions: An Overview of AIDS Interventions in High-Risk Groups; P. Lamptey. Intervention Research Needs for AIDS Prevention Among Commercial Sex Workers and Their Clients; B. de Zalduondo, et al. 7 additional articles. Index.

Deep Inelastic Scattering of Leptons and Tests of Quark/Parton Models (J.T. Londergan, S. Kumano). MesonExchange and Deep Inelastic Scattering (WY.P. Hwang, J. Speth). Hadronic Reactions in the QuasiElastic Peak Region (A. DePace). Gluons, Spin and Flavor in the LEP (F.E. Close). Flavor Production at Low Energies (R.A. Eisenstein). ChiralOdd Parton Distributions and Polarized DrellYan (R.L. Jaffe). Three Decades of Missing GamowTeller Strength (C.D. Goodman). Chiral Symmetry and Axial Charge Sum Rules (M. Kirchbach). SpontaneousSymmetry Breaking and GamowTeller States (F.C. Khanna et al.). Development and Application of FullFolding Optical Potentials (C. Alvarez et al.). Experimental Foundation for NN Interactions (J.A. Carr). The Continuum Spin Response to Intermediate Energy Protons at Low Momentum Transfer (F.T. Baker, C. Glashauser). 29 additional articles. Index.

Lipid Membrane Organization and Molecular Partitions: Determination of Lipid Asymmetry and Exchange in Model Membrane Systems (C. Tilcock et al.). Role of Macromolecules on Membrane Interaction: Pegylation of Membrane Surfaces (D. Fisher). Influence of Polar Polymers on the Aggregation and Fusion of Membranes (K. Arnold et al.). Role of Lipids and Proteins on Membrane Adhesion and Fusion: AnnexinPhospholipid Interactions in Membrane Fusion (P. Meers et al.). Evidence for Multiple Steps in Enveloped Virus Binding (A.M. Haywood). Physical Basis Underlying Membrane Adhesion and Fusion: Red Blood Cell Interaction with a Glass Surface (J.K. Angarska et al.). PhysicoChemical Factors Underlying Membrane Adhesion and Fusion (S. Ohki). Nine additional articles. Index.

Project Reviews: The Petten BNCT Project (R.L. Moss et al.). Reactor Neutron Souces: A Compact TRIGA Reactor for Boron Neutron Capture Therapy (W.L. Whittemore). Accelerator Neutron Sources: Accelerator Based Neutron Sources for Neutron Capture Therapy (E. Grusell). Dosimetry and Treatment Planning: Beyond the EpithermalNeutron Beam (F.J. Wheeler et al.). Dose Enhancement: Gadolinium as a Neutron Capture Therapy Agent (J.A. Shih, R.M. Brugger). Boron Chemistry General. Boron Chemistry BPA. Boron Macromolecules. Boron Analysis in Biological Samples. Boron Imaging. Radiobiology. Preclinical Animal Studies. Acute and Late Effects in Normal Tissues. Boron Biodistributions in Glioma Patients. Clinical Studies of Cancers with Poor Prognoses. One hundred thirtyone additional articles. Index.

Dendritic Cells in the Induction of Immunity.- Escape Mechanisms of Viruses from Immune Responses and Their Relevance to Vaccine Design.- Enhanced Immunogenicity of Recombinant and Synthetic Peptide Vaccines.- Immunomodulation by Adjuvants.- Use of Syntex Adjuvant Formulation to Enhance Immune Responses to Viral Antigens.- Influenza Vaccines and the Wyeth-Ayerst Experience with Syntex Adjuvant.- Nonionic Block Polymer Surfactants as Adjuvants in Vaccines.- Effects of Added Cytokines on Immune Responses and Memory.- The Assessment and Use of Adjuvants.- Efficient Anti-Idiotypic Immunization with Homologous, Virus Neutralizing Monoclonal Antibodies Conjugated with KLH and Combined with Quil A.- Protein Conformation Affects the Efficacy of Pertussis Vaccines.- Vaccination Against Epstein-Barr Virus.- Adenovirus Vectored Vaccines.- Vaccines Against Bacterial Infections of Children.- Current Progress and Future Trends in Birth Control Vaccines.- Contributors.

Plenary Papers.- Transformation Theory.- Systems Approach as a Style: A Hermeneutics of Systems.- Action and Structure in Problem Solving.- Implementing Total Quality Management Through Total Systems Intervention: A Creative Approach to Problem Solving in Diagnostic Biotechnology (PTE)LTD.- Five Commitments of Critical Systems Thinking.- A Scenario-Based Approach to Strategic Information Systems Planning.- Information Management.- Applications of Systems Thinking.- The Design of European Industrial Systems: A Systemic Investigation.- Modelling Medica: A Technology Transfer Systems Approach to the Evaluation of a European Community Funded Research Project in Medical Informatics.- The Social System of National Health Care and System of Human Society.- Systems Thinking in Organizational Analysis and Design.- Theories of Autonomous Systems: A Comparative Analysis.- Cybernetic Aspects of Management Systems Engineering.- Systems Evolution in Modern Systems Research and a Formal Model for Evolving Systems.- Organizational Closure and the Quantum View of Organizations.- Landscape Ecology as an Operational Framework for Environmental GIS: Zdarske Vrchy, Czechoslovakia.- Introducing Geographical Information Systems into British Local Government: Developments in Kirklees Metropolitan District.- Taking Systems Thinking into Schools.- Health and Safety Legislation - Threat or Opportunity?.- Examination of the Concept of 'Key Factor for Success' from a Systems Thinking Perspective.- A Systematic Approach to Learning from Past Experiences in a Diagnostic Problem-Solving Environment.- Interdisciplinarity and Self-Organization in Computational Neuroepistemology: An Alternative Methodological Approach to Cognitive Science.- Systems Thinking in Poland.- Old Confusion in New European Systems Thinking.- A Unified Systems Hypothesis.- Applications of Methodology (Both Hard and Soft).- Systems Thinking and Investigation of Digestive Secretion.- Variable Receptive Field System Transformation and its Applications to Visual Field.- An Experimental Approach to the Description of Contour Segments Using the Fourier-Bessell Transform.- Self-Organization in Rural Economic System.- A System Dynamics Approach to Assessing the Impact of Management Information Systems.- Stella Modelling Process for a Manpower Strategy.- An Urbanistic Project Based on General Systems Theory.- Analysis and Design of Socio-Economic Systems.- Are all Failures Systems Failures?.- Use of the VSM to Assist in the Establishment of an Engineering Consortium.- How Can We Use a "Hard" Method in a "Soft" Way? Lessons Learnt from Cases using "Rating Chart Methods".- Untangling the Perception Web: A Methodology.- Untangling the Perception Web: An Application.- Systems Practice: An Application of "Soft" Systems Thinking in the Context of IS Planning for Small Business.- Soft Systems in Software Design.- A First Step Towards the Automation of SSM?.- The Need for Tool Support for Soft Systems.- Tools Supporting Soft Systems.- Problem Structuring and Critical Systems Thinking.- A Generic Model for Scenario Analysis and Modelling.- A Problem Structuring Method.- Levels of Problem Structuring and Problem Definitions.- A Multiple Criteria Approach to Complex Situations.- The Role of the Analyst and the Choice of Methodology.- The Use of Social Paradigms in the Analysis of Team Behaviour During Organizational Change.- A Brief Introduction to Complementarism.- Participatory Research: An Emancipatory Methodology for Systems Practice.- The Sacred and Profane in Critical Systems Thinking.- Critical Systems Thinking: Real Fiction?.- The Critical Systems Methodologies and the "Truth of Invariability".- Interpretive Critical Ideologies for Research Methodologies.- Community Operational Research and the New Public Health Movement.- Which Evaluation Methodology When? A Contingency Approach to Evaluation.- The Systematization of Practice.- Timeo Danaos et Dona Ferentes: A Philosophical-Cum-Epistemological ...

Evaluation of Flat versus Complex Terrain Models in Estimating Pollutant Transport and Deposition in Complex Terrain; M.W. Yambert, et al. Small Particle Deposition in Air Quality Modeling; R. Kapahi. Accounting for Wet Deposition in Incinerator Risk Assessments; A.A. Campbell, et al. Accounting for Dry Deposition in Incinerator Risk Assessments; C.C. Travis, et al. Gas-Particle Distribution and Atmospheric Deposition of Semivolatile Organic COmpounds; T.F. Bidleman. An Overview of Food Chain Impacts from Municipal Waste Combustion; H.A. Hattemer-Frey, et al. Current Studies on Human Exposure to Chemicals with Emphasis on the Plant Route; S. Paterson, et al. Airto-Leaf Transfer of Organic Vapors to Plants; E. Bacci, et al. Uptake of Organic Contaminants by Plants; C. Mc Farlane. Uncertainties in Estimating Chemical Degradation and Accumulation in the Environment; S.T. Washburn, et al. The Food Chain as a Source of Human Exposure from Municipal Waste Combustion: An Uncertainty Analysis; G. Belcher, et al. Assessing Multiple Pathway Exposures: Variability, Uncertainty, and Ignorance; T.E. McKone. Uncertainty Analysis: An Essential Component of Risk Assessment and Risk Management; R. Tyler, et al. 3 additional articles. Index.

Some Problems in Limb Development.- The Molecular Basis of Limb Patterning: A Review.- Expression of the Msh-like Homeobox-containing Genes During Mouse Limb Development.- The Limb Deformity Gene Encodes Evolutionarily Highly Conserved Proteins.- The Role of Homeobox Genes in Amphibian Limb Development and Regeneration.- Homeobox-Containing Genes and Gap Junctional Communication in Pattern Formation During Chick Limb Development.- Functional Studies of Genes in the Limb.- Hox-7: Temporal Patterns of Expression in Normal and Limbless Chick Embryos.- Expression Profile of Two Homeobox Genes During Chicken Embryogenesis.- Characterisation of Three Zebrafish Genes Related to Hox-7.- A Comparison of the Expression Domains of the Murine Hox-4, RARs and CRABP Genes Suggest Possible Functional Relationships During Patterning of the Vertebrate Limb.- Retinoic Acid Nuclear Receptors.- The Role of Retinoic Acid and Cellular Retinoic Acid-Binding Protein in the Regenerating Amphibian Limb.- Retinoic Acid Treatment Alters the Pattern of Retinoic Acid Receptor Beta Expression in the Embryonic Chick Limb.- Expression Pattern of an RXR Nuclear Receptor Gene in the Chick Embryo.- Retinoic Acid and Limb Pattern Formation in Cell Culture.- Growth Factors Produced by the Polarising Zone - a Complement to the Retinoic Acid System.- Biochemical and Molecular Aspects of Retinoid Action in Limb Pattern Formation.- Position-Dependent Properties of Limb Cells.- Retinoic Acid and Limb Patterning and Morphogenesis.- Does Retinoic Acid Organise a Limb or Induce a ZPA?.- Retinoic Acid Effects on Experimental Chick Wing Buds: Patterns of Cell Death and Skeletogenesis.- A Comparison of Reaction Diffusion and Mechanochemical Models for Limb Development.- The Pathway of Polarising Activity from Hensen's Node to the Wing Bud in the Chick Embryo.- Extracellular Matrix in Early Limb Development.- Molecular Heterogeneity of Chondroitin Sulphate in the Developing Chick Limb.- Special Properties of the AER/Mesenchyme Interface in the Chick Wing Bud: Analysis of ECM Molecules and Integrin Receptors.- Physical Forces and Pattern Formation in Limb Development.- Extracellular Material Organization and Long Tendon Formation in the Chick Leg Autopodium. In Vivo and In Vitro Study.- Hyaluronan-Cell Interactions in Limb Development.- The Role of the Transforming Growth Factor-ß (TGF-ß) Family, Extracelluiar Matrix and Gap Junctional Communication in Limb Cartilage Differentiation.- Vascular Involvement in Cartilage and Bone Development.- Patterning of Connective Tissues in the Regenerating Amphibian Limb.- The Interdigital Spaces of the Chick Leg Bud as a Model for Analysing Limb Morphogenesis and Cell Differentiation.- A "Packaging Model" of Limb Development.- The Somite-Muscle Relationship in the Avian Embryo.- Observations Concerning the Control of Directed Myogenic Cell Migration.- Extracellular Matrix and Muscle Formation.- Control of Muscle Morphogenesis and Endplate Pattern in Limb Muscles of Avian Chimeras.- Review of the Extracellular Matrix in Relation to Limb Development.- Evolution of Connective and Skeletal Tissues.- Developmental Approaches to the Problem of Transformation of Limb Structure in Evolution.- New Palaeontological Contributions to Limb Ontogeny and Phylogeny.- The Fin-Limb Transformation: Palaeontological and Embryological Evidence.- The Development of the Teleost Fin and Implications for our Understanding of Tetrapod Limb Evolution.- Phylogenetically Ancient Pattern in Ontogenesis of Limb Muscles.- Mutation and Limb Evolution.- Insights into Limb Development and Pattern Formation from Studies of the Limbless and Talpid2 Chick Mutants.- Proximal Elements in the Vertebrate Limb: Evolutionary and Developmental Origin of the Pectoral Girdle.- Evolutionary Transformation of Limb Pattern: Heterochrony and Secondary Fusion.- Plasticity in Skeletal Development: Knee-Joint Morphology in Fibula-Deficient Chick Embryos.- The Implications of "The Bauplan" f

Morphology.- The Pineal Gland of Mammals: Some Open Morphological Questions.- Demonstration of Nerve Fibers Immunoreactive to met-Enkephalin, leu-Enkephalin, and ß-Endorphin in the Bovine Pineal Gland.- Comparative Studies of VIP-, PHI-, and NPY-Immunoreactive Nerve Fibers in the Pineal Gland of the Sheep.- Biochemistry.- Pharmacological Regulation of Receptor-Mediated Indoleamine Metabolism in the Mammalian Pineal Gland.- Regulation of Melatonin Synthesis and Release: Paracrine Relationships in Mammalian Pineal Gland.- New Aspects Concerning the Regulation of Pineal Indoleamine Metabolism: Implications for Neuroimmunology.- The Use of Perifusion Technique in the Research of Pineal Neuroendocrinology. The Role of Different Neurotransmitters in the Regulation of Pineal Melatonin Secretion.- Interferon-? Modulates Indoleamine Metabolism in Rat Pineal Gland in Organ Culture.- Melatonin Receptors.- High-affinity Melatonin Receptors in Mammals: Localization, G-Protein Coupling and Signal Transduction.- Melatonin Receptors in Discrete Areas of Rat and Hamster Brain: Modulation by Melatonin, Testosterone and the Photoperiod.- Melatonin Binding Sites in the Nervous and Immune Systems.- 2-?125I? Iodomelatonin Binding in Normal and Neoplastic Tissues.- Melatonin in the gastrointestinal tract.- Biochemical Characteristics of Melatonin Receptors in Different Organs and Translation of Hormonal Signal in the Nucleus.- Physiology.- Annual Changes in the Daily Pattern of Melatonin Synthesis and Release.- Integration of Environmental Signals by the Pineal Gland and its Significance for Seasonality in Small Mammals.- Opioid Involvement in Melatonin Action.- Effect of Melatonin on NADH-Oxidoreductase Activity and Cyclic Nucleotide Levels in Rat Adrenals.- Temporal Profile of Superoxide Dismutase Activity in the Pineal Gland and the Liver of Rats.- Pineal-Harderian Gland Interactions: Morphological and Physiological Evidences for an Endocrine Function of the Syrian Hamster Harderian Gland.- Melatonin Enhances GABA-Mediated Effects when Administered by Micropressure Ejection in Single Unit Neuronal Recordings.- Immunology.- Action of Melatonin on Immune System.- Opioids in Immune Cells.- Spleen Morphology and Lymphoproliferative Activity in Short Photoperiod Exposed Hamsters.- Melatonin Reconstitutes the Decreased CFU-S Content in the Bone Marrow of Hypothalamus - Lesioned Mice.- Oncology.- Melatonin Action on Oncogenesis.- The Effects of Melatonin and Melatonin Analogues on the P388, DLD-1 and MCF-7 Tumor Cell Lines.- Is there a Role for the Pineal Gland in Neoplastic Growth?.- Clinical Studies.- Melatonin, Immunity and Cancer in Humans.- Evidence for a Sex-Specific Facilitatory Effect of Melatonin on Prolactin Secretion. Is Pineal-Prolactin Interaction Relevant to the Clinical Course of Breast Cancer?.- Pineal-Interleukin 2 Interactions and their Possible Importance in the Pathogenesis of Immune Dysfunctions in Cancer.- Significance of Melatonin to Chronobiology: Immunological Correlations.- Circadian Profile of Serum Melatonin in Cushing's Syndrome and Acromegaly.- Urinary 6-Sulfatoxymelatonin Excretion in Breast Cancer Patients and Control Subjects.- Interindividuel Differences in the Responses of Serum and Salivary Melatonin to Light.- Contributors.

I - Money in Life.- 1. How Much is Enough?.- 2. Money Styles.- 3. Material Incentives in Childhood and Adolescence.- 4. Poverty and Psychopathology.- 5. Power, Gender and Money.- 6. Men, Money and Masculinity.- 7. Money as a Mirror of Marriage.- 8. Money and Divorce.- 9. Gambling.- 10. In the Matter of Setting the Value of Psychological Damages.- 11. Money in the Older Years.- II - Money in the Psychotherapeutic Setting.- 12. Sigmund Freud and Money.- 13. Money and the Left in Psychoanalysis.- 14. The Seduction of Money.- 15. Money and Countertransference.- 16. Countertransference Problems with Money.- 17. Money Issues and Analytic Neutrality.- 18. Psychoanalytic Understanding and Treatment of the Very Rich.- 19. Money Management in the Borderline Patient.- 20. Psychotherapy Without Fee.- 21. Money, Ethics and the Psychoanalyst.- 22. Fee and Empathy: Logic and Logistics in Psychoanalysis.- 23. The Fiscal Blindspot in Therapy.- 24. Effects of the New Economic Climate on Psychotherapeutic Practice.- Appendix Correspondence.

Characterization of Gene and Protein Structure.- Biosynthesis and Assembly of the Factor VIII-von Willebrand Factor Complex.- Factor IX: Gene Structure and Protein Synthesis.- Antithrombin III Genetics, Structure and Function.- Interactions Between the Functional Domains of Antithrombin III.- Protein C: Gene Structure and Protein Synthesis.- Structural and Functional Properties of Protein C.- Molecular Defects Affecting Hemostasis.- Molecular Defects in Hemophilia A.- Molecular Defects in Hemophilia B.- Molecular Defects in Human Antithrombin III Deficiency.- The Biologic Impact of Hereditary Defects that Cause Thrombosis.- Protein Production by Recombinant Technology.- Factors Limiting Expression of Secreted Proteins in Mammalian Cells.- Synthesis of Biologically Active Vitamin K-Dependent Coagulation Factors.- The Expression of Therapeutic Proteins in Transgenic Animals.- Clinical use of Proteins Produced by Recombinant Technology.- The Use of Animal Models to Evaluate Proteins Produced by Recombinant Technology.- Experiences with Recombinant Factor VIIa in Hemophiliacs.- Clinical Trials of Factor VIII Produced by Recombinant Technology.- Clinical Trials of Recombinant Factor VIII.- Concluding Overview.- The Impact of Recombinant Technologies in Understanding Plasma Proteins Important for Hemostasis and Thrombosis.- Contributors.

1. Prologue.- 2. Is Estrogen A Cellular Signal for Female Genital Tract Epithelium?.- 3. Reciprocal Tissue Interactions in Morphogenesis and Hormonal Responsiveness of the Female Reproductive Tract.- 4. Qualitative and Quantitative Morphology of Induction in Endometrial Epithelium.- 5. Interactions of Estrogens, Protooncogenes and Growth Factors.- 6. Expression of Metallothionein Genes in Preimplantation Embryos, Decidua and Placentae.- 7. Uterine Preparation for Blastocyst Attachment.- 8. Uterine Extracellular Matrix Remodeling in Pregnancy.- 9. Glycoprotein Expression and Function in Embryo-Uterine Interactions.- 10. Uterine-Conceptus Interactions During the Peri-implantation Period.- 11. Endocrine Functions of the Rodent Placenta: Placental Lactogens.- 12. The Origin and Role of Cytokines Determining Success and Failure in the Post-implantation Period.- 13. Epilogue.- Poster Presentations.- Contributors.

1: Early Adolescence: Behavior Problems, Stressors, and the Role of Family Factors.- 2: Epidemiology of Behavioral and Emotional Disorders of Adolescence: Implications for Treatment, Research, and Policy.- 3: Risk-Taking Behavior in Adolescence.- 4: Attention Deficits, Impulsivity, and Hyperactivity With or Without Conduct Problems: Relationships to Delinquency and Unique Contextual Factors.- 5: A Multisystemic Approach to the Treatment of Serious Delinquent Behavior.- 6: Empirical Bases for Integrating School- and Family-Based Interventions Against Early Adolescent Substance Abuse.- 7: Anorexia Nervosa and Bulimia Nervosa: What Knowledge of Diagnosis and Pathogenesis Has Taught About Treatment.- 8: Strategic Adaptations of Cognitive-Behavioral Therapy for Anorexic and Bulimic Adolescents and Their Families.- 9: Suicide in the Young: Implications for Policy and Programming.- 10: Effective Caregiver Behavior in Working With Suicidal Adolescents.- 11: A Cognitive-Behavioral Model for the Treatment of Social-Communicative Deficits in Adolescents with Autism.- 12: Severe School-Related Behavior Problems in Adolescents: The Use of a Home-Based Interpersonal Treatment Model With Parents as Mediators.- 13: Towards a Unified Perspective on Human Service Delivery Systems: Application of the Teaching-Family Model.- 14: Adolescent Mental Health Promotion: Policy and Practice.

I. Introduction: General Issues in Developmental Disorders.- 1 State of the World's Children: Developmental-Behavioral Disorders in a Global Context.- 1. Introduction.- 2. Children in History.- 3. Children Today.- 4. Recent Nutrition Data.- 5. Children Tomorrow.- 6. Conclusions.- References.- 2 PL 99-457: A New Challenge and Responsibility for Physicians.- 1. Introduction.- 2. Physician Involvement.- 2.1. Identification.- 2.2. Medical Evaluation.- 2.3. Communication with the IFSP Team.- 2.4. Family Support.- 2.5. Participation in the IFSP Process.- 2.6. Advocacy.- 3. Barriers to Physician Involvement.- 4. Overcoming Barriers.- Selected Readings.- 3 An Ethical Issue in Developmental Pediatrics: Analysis and Discussion of a Case History.- Case History-S. L., a Newborn with Partial Trisomy-13.- Reference.- Selected Readings: Ethical-Legal Issues.- 4 A Physician's Primer of Developmental and Psychologic Test Instruments.- 1. Introduction.- 2. Possible Developmental Delay.- 2.1. Developmental (Cognitive/Motor) Delay.- 2.2. Language Delay.- 2.3. Behavioral/Adaptive Delays.- 3. Cases Involving Suspected Developmental Delay.- 4. Difficulties in School Performance.- 4.1. Intelligence.- 4.2. Academic Achievement.- 4.3. Perceptual/Visual Motor.- 4.4. Attention/Concentration.- 4.5. Behavioral.- 5. Cases Involving Suspected School Problems.- 6. Conclusions.- References.- II. Developmental Disorders.- 5 Neonatal Brain Care: Does Early Developmental Intervention Work?.- 1. Introduction.- 2. Supplemental Stimulation.- 3. Protection at All Costs.- 4. Contingency-Based and Developmentally-Based Interventions.- 5. Summary.- References.- 6 Early Identification of Cerebral Palsy.- 1. Introduction.- 2. Types of Cerebral Palsy.- 3. Early Clinical Signs of Cerebral Palsy.- 3.1. Amiel-Tison et al. (1977).- 3.2. Ellenberg and Nelson (1981).- 3.3. Harris (1987).- 3.4. Research Conclusions.- 4. Summary.- References.- 7 Movement Disorders and Paroxysmal Behaviors in Children and Adolescents.- 1. Introduction.- 2. Disorders Characterized by Alteration in the State of Consciousness and Abnormal Movements.- 2.1. Seizure Disorders.- 2.2. Pseudoseizures.- 3. Disorders Characterized Primarily by an Alteration in Consciousness.- 3.1. Syncope Due to Inadequate Cerebral.- 3.2. Postural Hypotension.- 3.3. Steal Syndromes.- 3.4. Cardiac Arrhythmias.- 3.5. Breath Holding Spells.- 3.6. Syncope Due to Hypoxia or Hypoglycemia.- 4. Disorders Characterized Primarily by Abnormal Movements.- 4.1. Disorders Characterized by Hyperkinesia.- 4.2. Disorders Characterized Primarily by Abnormalities of Posture and Tone.- 4.3. Disorders Characterized Primarily by Akinesia.- 5. Other Paroxysmal Disorders.- 5.1. Rett Syndrome.- 5.2. Mannerisms.- References.- 8 Epilepsy: Implications for Intelligence, Learning, and Behavior.- 1. Introduction.- 2. Epilepsy and Intelligence.- 3. Epilepsy and Learning Difficulties.- 4. Epilepsy and Childhood Emotional and Behavioral Disorders.- 4.1. Anticonvulsants and Behavior Disorders.- 4.2. Temporal Lobe Epilepsy and Psychiatric Disorders.- 5. Summary.- References.- 9 Learning Disabilities: "The Good News/The Bad News".- 1. Introduction.- 2. Toward a Definition.- 3. Significant Discrepancy.- 4. Research.- 5. The Future.- References.- 10 Lessons I've Learned from Learning Disabilities.- 1. Introduction.- 2. Overlooked Learning Disability.- 2.1. Emotional Disturbance and Underachievement.- 2.2. Headaches and Fatigue.- 3. Miscellaneous Lessons I Have Learned.- 3.1. "Abnormal Depth Perception" in a Clumsy Child.- 3.2. Involuntary Movements with Accompanying Behavioral Upset.- 3.3. Refusal to Speak in an Anxious Child.- 3.4. Cerebral Palsy with Accompanying Depression.- 3.5. Newly Acquired Perceptual Disorder in an Intelligent Child.- 3.6. Situational Depression with a Well-Controlled Seizure Disorder.- 3.7. Acute Psychosis with Temporal Lobe Epilepsy.- 3.8. Declining School Performance and the Misdiagnosis of Seizures.- 3.9. Adolescent Stroke with Com...

Invited Papers.- Theory of Electron Collisions in Partially Ionized Gases.- Electron Collisions with Molecules.- Electron Transport in Partially Ionized Gases.- Non Equilibrium Plasma Kinetics.- Modeling High Pressure Electric Discharges: Applications to Excimer Lasers.- Energy Transfer in Atom/Molecule Collisions with Molecules and Surfaces.- Reactivity Calculations for Elementary Atom-Diatom Processes and Applications to Non-Equilibrium Systems.- Excimer Lasers: Status and Perspectives.- Fundamental Properties of RF Glow Discharges: An Approach Based on Self-Consistent Numerical Models.- Theory of High-Frequency Discharges.- Volume Production of Hydrogen Negative Ions.- Laser Diagnostics of a Hydrogen Discharge.- Hydrogen-Surface Interactions.- Plasma Assisted Thin Film Production WC, a-C: H and Diamond Films.- Electric Discharge Lamps.- Contributed Papers.- Inelastic Scattering of Electrons From H2 Molecule and First-Born Approximation: Role Of Correlation.- Electron-Molecule Collision Cross Sections for Etching Gases.- Electron Collisions in Gas Switches.- Theory of e- -Diatom Scattering at Low Energies.- A Parameter-Free Theoretical Model for Low-Energy Electron Scattering from Polyatomic Molecules.- Electron Collision Cross-Sections Determined from Beam and Swarm Data by Boltzmann Analysis.- Electron Collision Cross Sections Involving Excited States.- Electron Collision Cross Sections Involving Excited States.- New Theoretical Approaches for Studying Electron Collisions with Small Molecules.- Ion-Neutral Reactions.- Energy Pooling Collisions: A Step Towards Ionization.- Potential Energy Curves of Open Shell Systems (Excimers) from Molecular Beam Scattering.- Molecular Beam Measurements of Ionization Cross Sections Relevant to Thermal Plasmas and Excimer Laser Systems.- The Silent Discharge and Its Application to Ozone and Excimer Formation.- Non Equilibrium Excimer Laser Kinetics.- Study of A Photoswitched Discharge for Excimer Laser.- A Self-Consistent Monte Carlo Modeling of RF Non-Equilibrium Plasma.- Charged Particles Dynamics in Electropositive Glow Discharges Probed by Optical Diagnostics.- Problems in the Experimental Determination of Electron Energy Distribution Function in RF Discharges.- Spectroscopic Diagnostics in the Cathode Fall and Negative Glow of a Nitrogen Glow Discharge.- Electron Kinetics in RF Discharges.- A Radiofrequency Trap for Tests on Production and Excitation of Ions.- Gas-Phase and Gas-Surface Interactions of Vibrationally Excited Hydrogen Molecules.- Translational Energy Distribution Functions of H+ and H in H2 Volume Discharges.- Numerical Simulation on Tandem Negative Ion Source.- Atomic and Molecular Surface and Volume Processes in the Analysis of Negative Hydrogen Discharges.- Interpretation and Analysis of the H2 Vibrational Distribution in a Hydrogen Discharge.- Electron Energy Distribution Functions in Magnetic Multipole Plasmas.- Effects Due to Negative Ions and Particles in Plasmas.- Electron and Vibrational Kinetics in Molecular Discharges.- Laser Diagnostic of Radio-Frequency Oxygen Plasma.- Spectroscopy and Kinetics of an Oxygen Glow Discharge.- Simulation Work in Noble Gas Radiation Detectors.- A Description of The Non-Equilibrium Behavior of Electrons in Matter: Macro-Kinetics.- Thermalization and Transport of Sputtered Particles in Glow Discharges.- The Free Electron Laser: A Simple Quantum Picture.- Electron and Photon Collisions in Strong Laser Fields.- Resonant Photopumping of Lithiumlike Ions in Laser-Produced Plasmas.- Ionization and Deionization of Electron Beam Disturbed Air.- Re-Entry Problems.- Diagnostics of Atomic Species Near the Electrodes of a Fluorescent Lamp.- Excited State Diagnostics in High Pressure Arc Lamps.- Participants.

1 Base oils from petroleum.- 1.1 Introduction.- 1.2 Base oil composition.- 1.2.1 Components of crude oil.- 1.2.2 Characteristics of the hydrocarbons for lubricant performance.- 1.2.3 Crude oil selection for base oil manufacture.- 1.3 Products and specifications.- 1.3.1 Physical properties.- 1.3.2 Chemical properties.- 1.3.3 Base oil categories.- 1.4 Conventional base oil manufacturing methods.- 1.4.1 Historic methods.- 1.4.2 Base oil manufacture in a modern refinery.- 1.4.3 Base oil production economics.- 1.4.4 Distillation.- 1.4.5 De-asphalting.- 1.4.6 Solvent extraction.- 1.4.7 Solvent de-waxing.- 1.4.8 Finishing.- 1.5 Modern catalytic processes.- 1.5.1 Severe hydro treatment.- 1.5.2 Special base oils from hydrocracking.- 1.5.3 Special base oils by wax isomerisation.- 1.5.4 Catalytic de-waxing.- 1.6 Future developments.- References.- 2 Synthetic base fluids.- 2.1 Introduction.- 2.2 Polyalphaolefins.- 2.2.1 Free radical oligomerisation.- 2.2.2 Ziegler catalysed oligomerisation.- 2.2.3 Friedel-Crafts catalysed oligomerisation.- 2.3 Alkylated aromatics.- 2.3.1 Introduction.- 2.3.2 Production and general properties.- 2.3.3 Applications.- 2.4 Polybutenes.- 2.4.1 Introduction.- 2.4.2 Production and general chemical properties.- 2.4.3 Application of PIB fluids.- 2.5 Synthetic esters.- 2.5.1 Introduction.- 2.5.2 Ester types.- 2.5.3 Manufacture of esters.- 2.5.4 Physicochemical properties of ester lubricants.- 2.5.5 Application areas.- 2.5.6 Future trends.- 2.6 Polyalkylene glycols.- 2.6.1 Introduction.- 2.6.2 Production.- 2.6.3 Chemistry.- 2.6.4 Key properties.- 2.6.5 Applications.- 2.7 Phosphate esters.- 2.7.1 Introduction.- 2.7.2 Manufacture.- 2.7.3 Physical and chemical properties.- 2.7.4 Applications.- References.- 3 Detergents/dispersants.- 3.1 Introduction.- 3.2 Detergents.- 3.2.1 Sulfonates.- 3.2.2 Phenates/salicylates/phosphonates.- 3.2.3 Detergent classification.- 3.3 Dispersants.- 3.4 Other lubricants.- 3.4.1 Automatic transmission fluids (ATFs).- 3.4.2 Gear lubricants.- 3.4.3 Tractor hydraulic oils.- 3.5 Performance evaluation.- References.- Further reading.- 4 Oxidative degradation and stabilisation of mineral oil based lubricants.- 4.1 Introduction.- 4.2 Autoxidation of hydrocarbons.- 4.2.1 Oxidation of hydrocarbons at low temperature (30-120°C).- 4.2.2 Oxidation of hydrocarbons at high temperature (> 120°C).- 4.2.3 Metal catalysed autoxidation of hydrocarbons.- 4.3 Oxidation stability of base oils.- 4.4 Inhibition of oxidative degradation of lubricants.- 4.4.1 Radical scavengers.- 4.4.2 Hydroperoxide decomposers.- 4.4.3 Multifunctional additives.- 4.4.4 Synergism between antioxidants.- 4.5 Application of antioxidants.- 4.5.1 Industrial lubricants.- 4.5.2 Engine oil.- 4.6 Future antioxidant technology.- 4.6.1 Antioxidants for industrial lubricants.- 4.6.2 Antioxidants for engine oils.- Acknowledgements.- References.- 5 Viscosity index improvers and thickeners.- 5.1 Introduction.- 5.2 Overview of VI improver chemistry.- 5.3 Chemistry and manufacture of commercial VI improvers.- 5.3.1 Polymethacrylates.- 5.3.2 Olefin copolymers.- 5.3.3 Hydrogenated styrene-diene copolymers.- 5.3.4 Styrene polyester.- 5.3.5 Concentrate-compatible PMA/OCP blends.- 5.4 Function and properties.- 5.4.1 Solution properties.- 5.4.2 Mechanism offunction.- 5.4.3 Shear stability.- 5.4.4 Thermal-oxidative stability.- 5.5 Performance.- 5.5.1 Low temperature viscosity.- 5.5.2 High temperature viscosity.- 5.5.3 Deposits.- 5.6 Prognosis for future developments.- References.- 6 Miscellaneous additives.- 6.1 Friction modifiers.- 6.1.1 Introduction.- 6.1.2 Friction and lubricating regimes.- 6.1.3 Friction modifier mechanisms.- 6.1.4 Chemical aspects of friction modifiers.- 6.2 Pour point depressants.- 6.2.1 Low temperature operations.- 6.2.2 Mechanism of pour point depressants.- 6.2.3 Pour point depressant additives.- 6.3 Demulsifiers and antifoams.- 6.3.1 Introduction.- 6.3.2 Emulsion stabilisation.- 6.3.3 Demulsification.- 6.3.4 Demulsifiers.- 6.3.5 Fo

One Introduction to Total Quality Management (TQM).- 1 - Total Quality Management - worldwide effect.- 2 - The management methodology.- 3 - TQM principles.- Two Implementation of TQM.- 4 - The executive/management role.- 5 - TQM structure and top-down requirements.- 6 - Quality policy.- 7 - Measurement.- 8 - Quality improvement teams.- 9 - Education and training.- 10 - Involvement and commitment.- 11 - Supplier strategy.- 12 - Time to market.- 13 - Organizational design.- 14 - Summary.- Three Tools and Techniques for TQM.

1 The origin and concept of HACCP.- 1.1 Introduction.- 1.2 Development of the HACCP concept.- 1.2.1 HACCP - A new approach.- 1.2.2 HACCP - A preventative system.- 1.3 Acceptance of HACCP by the food industry.- 1.3.1 Establishment of HACCP by other companies.- 1.3.2 Role of various agencies.- 1.4 Summary.- References.- 2 The HACCP system and how it fits into FSIS programs.- 2.1 Introduction.- 2.1.1 FSIS background.- 2.1.2 Industrial responsibility and HACCP.- 2.1.3 FSIS and HACCP.- 2.2 HACCP study.- 2.2.1 Background.- 2.2.2 Consultations and public hearings.- 2.2.3 Workshops.- 2.3 Critical control points for various models.- 2.3.1 Refrigerated foods (cooked and assembled) critical control points.- 2.3.2 Raw beef pattie critical control points.- 2.3.3 Whole young chickens critical control points.- 2.3.4 Cooked sausage critical control points.- 2.3.5 Pork slaughter market hogs critical control points.- 2.4 In-plant testing of HACCP models.- 2.4.1 Background.- 2.4.2 Plant specific plan.- 2.4.3 Inspection during phases II and III.- 2.4.4 Phase II: Implementation.- 2.4.5 Phase III: Operational.- 2.5 Evaluation.- 2.5.1 Background.- 2.5.2 Limitations.- 2.5.3 HACCP model checklist.- 2.5.4 National profiles.- 2.5.5 Quantitative plant data.- 2.5.6 Qualitative plant data.- 2.5.7 Inspector and plant personnel survey.- 2.5.8 Workshop evaluation.- 2.5.9 Training.- 2.5.10 In-plant changes.- 2.6 Current HACCP issues.- 2.6.1 Voluntary/mandatory.- 2.6.2 Review of HACCP plans.- 2.6.3 Transition period.- 2.6.4 Plan approval.- 2.6.5 Critical limits.- 2.6.6 Generic models.- 2.6.7 Training.- 2.6.8 Plan failure.- 2.6.9 Safety/economic.- 2.6.10 Other quality systems.- 2.6.11 Scientific validity.- 2.7 Quadrilateral discussions on food safety.- 2.7.1 Introduction.- 2.7.2 HACCP working group.- 2.7.3 HACCP working group report.- 2.8 Summary.- References.- 3 Implementation of HACCP program on farms and ranches.- 3.1 Introduction.- 3.2 Livestock quality assurance programs.- 3.3 Implementing HACCP on livestock units.- 3.3.1 Initiating on-farm HACCP preventive medicine programs.- 3.3.2 Hazard identification.- 3.3.3 Flow diagrams.- 3.4 Conclusion.- References.- 4 Implementation of the HACCP program by meat and poultry slaughterers.- 4.1 Introduction.- 4.2 Purpose of HACCP.- 4.2.1 Selection of team members.- 4.2.2 Training of HACCP team.- 4.3 Development of the HACCP program.- 4.3.1 Selection of the HACCP team coordinator.- 4.3.2 Development of the master HACCP program.- 4.4 Implementation of the HACCP program.- 4.4.1 Support of management.- 4.4.2 Fitting HACCP plan into operations.- 4.4.3 Focusing attention on hazards.- 4.4.4 Product specific HACCP programs.- 4.5 Summary.- References.- 5 The use of HACCP for producing and distributing processed meat and poultry products.- 5.1 Introduction.- 5.2 Reasons for using HACCP.- 5.3 Developing HACCP plans.- 5.4 Hazard analysis and risk assessment.- 5.4.1 Product recalls.- 5.4.2 Epidemiological data.- 5.4.3 Chemical hazards.- 5.4.4 Physical hazards.- 5.4.5 Biological hazards.- 5.5 Critical control points and critical limits.- 5.5.1 Formulating.- 5.5.2 Cooking.- 5.5.3 Cooling.- 5.5.4 Holding.- 5.5.5 Packaging.- 5.5.6 Preventing recontamination.- 5.5.7 Storing and distributing.- 5.6 Monitoring.- 5.7 Corrective action.- 5.8 Record keeping.- 5.9 Verification.- 5.10 Should HACCP be mandatory?.- 5.11 Summary.- References.- Addendum - Guideline for writing operating instructions/HACCP plans for processed meat and poultry products.- A.1 Headings.- A.2 Critical Control Point (CCP).- A.3 Control Point (CP).- 6 Implementation of the HACCP program by the fresh and processed seafood industry.- 6.1 Introduction.- 6.2 Significance of the seafood industry.- 6.2.1 Resources.- 6.2.2 Fishery habitats.- 6.2.3 US imports of fishery products.- 6.2.4 US exports of fishery products.- 6.2.5 Challenges facing the US seafood industry.- 6.2.6 Food safety in the US fishery system.- 6.3 HACCP in the seafood industry.- 6.3.1 Background.- 6.3.2 Bene...

List of Tables. List of Figures. List of Acronyms. Introduction and Background Information. Exposure and Hazard Assessment Working Group. Technology Assessment Working Group. Management of Activities.