Books in the Advances in Biochemical Engineering/Biotechnology series

This book provides a comprehensive overview of current biosurfactant research and applications. Public awareness of environmental issues has increased significantly over the last decade, a trend that has been accompanied by industry demands for climate-friendly and environmentally friendly renewable raw materials. In the context of household products, biosurfactants could potentially meet this demand in the future due to their low ecotoxicity, excellent biodegradability, and use of renewable raw materials. The diversity of this class of molecules, which has only been marginally tapped to date, offers only an inkling of their future application potential. However, there are two main obstacles to their widespread commercial use on the growing surfactant market: the lack of attractive and competitive production technologies, and the limited structural diversity of commercially available biosurfactants. Addressing both of these core issues, this book will provide readers with a deeper understanding of the role of biosurfactants, including future opportunities and challenges.Chapter "e;Environmental Impacts of Biosurfactants from a Life Cycle Perspective: A Systematic Literature Review"e; is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

This book offers a comprehensive review of the latest developments, challenges and trends in C1-based (one-carbon based) bioproduction, and it presents an authoritative account of one-carbon compounds as promising alternative microbial feedstocks. The book starts with a perspective on the future of C1 compounds as alternative feedstocks for microbial growth, and their vital role in the establishment of a sustainable circular carbon economy, followed by several chapters in which expert contributors discuss about the recent strategies and address key challenges regarding one or more C1 feedstocks. The book covers topics such as acetogenic production from C1 feedstocks, aerobic carboxydotrophic bacteria potential in industrial biotechnology, bioconversion of methane to value-added compounds, combination of electrochemistry and biology to convert C1 compounds, and bioprocesses based on C1-mixotrophy. Particular attention is given to the current metabolic engineering, systems biology, and synthetic biology strategies applied in this field.

This book reviews the latest trends in glycobiotechnology, it offers an authoritative discussion about future directions of glycoengineering, and it provides a comprehensive overview about the current and emerging approaches to identify, quantify and characterize glycosylated proteins.Divided into 14 chapters, the book outlines recombinant glycoprotein expression in mammalian cells, insect cells, yeast, and bacterial systems. It covers the chemical and enzymatic syntheses of glycans and glyconjugates, and addresses the impact of glycosylation on protein function for the development of biologicals including vaccines. In the final chapters of the book, readers will discover more about the state-of-the-art in glycomics, glycoproteomics and glycan array technologies.

Enzymes that are operationally stable at high pH (also known as alkaline active enzymes) are desirable in several applications such as detergent formulating and leather tanning processes, and they are among the major selling enzymes and the most important industrial enzymes.

This book offers an authoritative review of biopharmaceuticals and their clinical relevance.

Although the catalytic activity of nucleic acid enzymes is usually much slower than that of proteins, nucleic acid enzymes with comparable catalytic activity have been obtained using stringent selection processes.

Although ionic liquids are considered "green solvents", the contributing authors will also explore their environmental impact when applied to biotechnology. Chemical, biological and medical scientists interested in ionic liquids and biotechnology will find this work instructive and informative.

This book reviews the development, characterization and applications of aptamers in different areas of biotechnology ranging from therapeutics to diagnostics and protein purification. Hailed as chemical antibodies, these single-stranded nucleic acid receptors were predicted to supersede antibodies in traditional assays, such as ELISA, within a short time. While this has yet to happen, readers will find in this book a deep insight into the progress of aptamer technology and a critical discussion about the limitations that need to be overcome in order to find wider acceptance and use outside of the still relatively small aptamer-community.This book covers all aspects of aptamer generation and application for the aptamer-experienced reader and curious novice alike, with the addition of an industry perspective on the future of aptamer-use in biotechnology.

Enzymes that are operationally stable at high pH (also known as alkaline active enzymes) are desirable in several applications such as detergent formulating and leather tanning processes, and they are among the major selling enzymes and the most important industrial enzymes.

Part I: Introduction.- The Sustainability and Life Cycle Assessments of Industrial Biotechnology: An Introduction.- Part II: Background.- History, Current State, and Emerging Applications of Industrial Biotechnology.- Economic Aspects of Industrial Biotechnology.- Part III: Industrial Biotechnology from an Assessment Perspective.-  Environmental Aspects of Industrial Biotechnology.- Societal and Ethical Aspects of Industrial Biotechnology.- Sustainability and Life Cycle Assessments in Industrial Biotechnology: A Review of Current Approaches and Future Needs.-  Social Life Cycle Assessment for Industrial Biotechnology.- Part IV: Specific Methods and Applications.- Assessing Land Use and Biodiversity Impacts of Industrial Biotechnology.- Risk Assessment of Processes and Products in Industrial Biotechnology.- Green Chemistry and its Contributions to Industrial Biotechnology.-  Application of geobiotechnology in mining, mineral processing and metal recycling.- Assessing Industrial Biotechnology Products with LCA and Eco-Efficiency.

This book offers an authoritative review of biopharmaceuticals and their clinical relevance.

Although the catalytic activity of nucleic acid enzymes is usually much slower than that of proteins, nucleic acid enzymes with comparable catalytic activity have been obtained using stringent selection processes.

This book reviews the latest advances in multiple fields of plant biotechnology and the opportunities that plant genetics, genomics and molecular biology have offered for agriculture improvement.