We a good story
Quick delivery in the UK

The Gliocentric Brain

About The Gliocentric Brain

The brain is the body¿s most vulnerable organ due to the defined roles of neurons within circuits. Neurons are vastly outnumbered by microglia, astrocytes, oligodendrocytes, macrophages, cells of the blood brain barrier and invading immune cells. These cells display different grades of reactivities and interactions. They integrate their responses and not only change phenotypes but can also completely reprogram after damage to protect the neuronal complexity. The interactions of these satellite cells in the healthy brain are described as well as their roles in all major brain diseases. Special emphasis is put on immune system ¿ brain interactions and regenerative and repair processes. The gliotic response is compared with the reactions to injuries of the skin and other organs. A final chapter addresses the definition of a cell type. It concludes that cell types can no longer be regarded as defined entities over the body¿s lifetime but are prone to phenotype plasticity and even complete reprograming.

Show more
  • Language:
  • English
  • ISBN:
  • 9783031481048
  • Binding:
  • Hardback
  • Pages:
  • 260
  • Published:
  • January 25, 2024
  • Edition:
  • 24001
  • Dimensions:
  • 160x20x241 mm.
  • Weight:
  • 559 g.
Delivery: 2-4 weeks
Expected delivery: July 11, 2024

Description of The Gliocentric Brain

The brain is the body¿s most vulnerable organ due to the defined roles of neurons within circuits. Neurons are vastly outnumbered by microglia, astrocytes, oligodendrocytes, macrophages, cells of the blood brain barrier and invading immune cells. These cells display different grades of reactivities and interactions. They integrate their responses and not only change phenotypes but can also completely reprogram after damage to protect the neuronal complexity. The interactions of these satellite cells in the healthy brain are described as well as their roles in all major brain diseases. Special emphasis is put on immune system ¿ brain interactions and regenerative and repair processes. The gliotic response is compared with the reactions to injuries of the skin and other organs. A final chapter addresses the definition of a cell type. It concludes that cell types can no longer be regarded as defined entities over the body¿s lifetime but are prone to phenotype plasticity and even complete reprograming.

User ratings of The Gliocentric Brain



Join thousands of book lovers

Sign up to our newsletter and receive discounts and inspiration for your next reading experience.