Books in the Wiley Series on Mass Spectrometry series

Mass spectrometry is a powerful analytical technique used to identify unknown compounds, to quantify known materials, and to elucidate the structural and chemical properties of molecules. Inorganic mass spectrometry focuses on the analysis of metals and elements rather than organic compounds.

Mass spectrometry (MS) is a crucial method in ensuring the production, quality, and safety of grape, wine, and grape-derivative products. This book concisely presents the applications of mass spectrometry in the analysis of wine, from traditional to more recent developments.

Provides an overview of the use of mass spectrometry (MS) for the analysis of pesticide residues and their metabolites.

The purpose of the book is to introduce platelets, and their functional role in thrombotic and cardiovascular disease, justifying the relevance of platelet proteomics research. Focus then shifts to the recent developments on mass spectrometry (MS)-based proteomics.

The last few years have seen an unprecedented drive toward the application of proteomics to resolving challenging biomedical and biochemical tasks. Separation techniques combined with modern mass spectrometry are playing a central role in this drive. This book discusses the increasingly important role of mass spectrometry in proteomic research, and emphasizes recent advances in the existing technology and describes the advantages and pitfalls as well.* Provides a scientifically valid method for analyzing the approximatey 500,000 proteins that are encoded in the human genome* Explains the hows and whys of using mass spectrometry in proteomic analysis* Brings together the latest approaches combining separation techniques and mass spectrometry and their application in proteome analysis* Comments on future challenges and how they may be addressed* Includes sections on troubleshooting

Covers the area of lipidomics from fundamentals and theory to applications* Presents a balanced discussion of the fundamentals, theory, experimental methods and applications of lipidomics* Covers different characterizations of lipids including Glycerophospholipids; Sphingolipids; Glycerolipids and Glycolipids; and Fatty Acids and Modified Fatty Acids* Includes a section on quantification of Lipids in Lipidomics such as sample preparation; factors affecting accurate quantification; and data processing and interpretation* Details applications of Lipidomics Tools including for Health and Disease; Plant Lipidomics; and Lipidomics on Cellular Membranes

With its detailed and systematic coverage of the current state of biophysical mass spectrometry (MS), here is one of the first systematic presentations of the full experimental array of MS-based techniques used in biophysics, covering both fundamental and practical issues.

Provides comprehensive coverage of the interpretation of LC-MS-MS mass spectra of 1300 drugs and pesticides* Provides a general discussion on the fragmentation of even-electron ions (protonated and deprotonated molecules) in both positive-ion and negative-ion modes* This is the reference book for the interpretation of MS-MS mass spectra of small organic molecules* Covers related therapeutic classes of compounds such as drugs for cardiovascular diseases, psychotropic compounds, drugs of abuse and designer drugs, antimicrobials, among many others* Covers general fragmentation rule as well as specific fragmentation pathways for many chemical functional groups* Gives an introduction to MS technology, mass spectral terminology, information contained in mass spectra, and to the identification strategies used for different types of unknowns

This volume describes the complete process of analyzing protein sequences by mass spectrometry including sample preparation, analysis, and data interpretation at a practical level. It provides sufficient experimental detail to carry out the experiments and consistently achieve good results.

Principles of Mass Spectrometry Applied to Biomolecules teaches readers how to use what they know about Mass Spectrometry's advantages and limitations to develop novel ways of using the technique for the analysis of proteins and other biomolecules.